DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11597 and PPT1

DIOPT Version :9

Sequence 1:	NP_001036602.1	Gene:	CG11597 / 39337	FlyBaseID:	FBgn0036212	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_011639.3	Gene:	PPT1 / 853023	SGDID:	S000003355	Length:	513	Species:	Saccharomyces cerevisiae

Alignment Length:	289	Identity:	110/289 - (38%)
Similarity:	155/289 - (53%)	Gaps:	21/289 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LPRELEVRQLCRSLSDLLVGESNLLSLQ---SPQI---VCGDIHGQFEDLLHLLELGGSV-QEHR 84
            ||::. |..:......|...|.:::.|:   :|.:   ||||.||||.|:|:|....|.| .:|.
Yeast   209 LPKKY-VAAIISHADTLFRQEPSMVELENNSTPDVKISVCGDTHGQFYDVLNLFRKFGKVGPKHT 272

  Fly    85 YLFLGDLVDRGKNSVETFLLLAALKVRHPAQVSLLRGNHECRSATRSYGFYEECLSRYGSANVWR 149
            |||.||.||||..|.|..||...||:.||....|.|||||..:..:.|||.:||..:| |..::.
Yeast   273 YLFNGDFVDRGSWSCEVALLFYCLKILHPNNFFLNRGNHESDNMNKIYGFEDECKYKY-SQRIFN 336

  Fly   150 MCCRVFDLLPLAAIIDGNILCVHGGLSPD-MQRLDDLRSLDRCHEIPESGIIADLLWSDPQEAPG 213
            |..:.|:.||||.:|:.:.|.:||||..| ...|.|.:::||..:.|..|...:|||:|||||.|
Yeast   337 MFAQSFESLPLATLINNDYLVMHGGLPSDPSATLSDFKNIDRFAQPPRDGAFMELLWADPQEANG 401

  Fly   214 WAASPRGHGKLFGGDVVEEFTRANGISLICRAHQLAQDGFRWHFGQLLVTIWSAPNYCYRCGNKA 278
            ...|.||.|..||.|:.:.|.|.|.:..|.|:|:|...|.::.....|:|::||||||...||..
Yeast   402 MGPSQRGLGHAFGPDITDRFLRNNKLRKIFRSHELRMGGVQFEQKGKLMTVFSAPNYCDSQGNLG 466

  Fly   279 AILR-------LNAAGDYD----FKVFEA 296
            .::.       |.|..:.|    .:.|||
Yeast   467 GVIHVVPGHGILQAGRNDDQNLIIETFEA 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11597	NP_001036602.1	PTZ00239	12..307	CDD:173488	110/289 (38%)
CG11597	NP_001036602.1	MPP_superfamily	12..296	CDD:301300	108/287 (38%)
PPT1	NP_011639.3	PLN03088	10..>130	CDD:215568
		TPR repeat	12..40	CDD:276809
		TPR repeat	45..75	CDD:276809
		TPR repeat	80..108	CDD:276809
		MPP_PP5_C	165..508	CDD:277362	110/289 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810