DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11597 and ppef1

DIOPT Version :9

Sequence 1:	NP_001036602.1	Gene:	CG11597 / 39337	FlyBaseID:	FBgn0036212	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	XP_021335306.1	Gene:	ppef1 / 559132	ZFINID:	ZDB-GENE-080303-27	Length:	729	Species:	Danio rerio

Alignment Length:	434	Identity:	106/434 - (24%)
Similarity:	163/434 - (37%)	Gaps:	158/434 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MMSALCPEAMNDADRLVENLRHVPVRLPRELEVRQLCRSLSDLLVGESN-LLSL----------- 53
            ::|.|....::.....|..|::..:.:|......:|...||   |.::| |||.
Zfish    94 LISHLLDSVVDPLTEEVRQLKYEQIMVPESYSGPRLSFPLS---VTDTNALLSAFKEEQTLHGKY 155

  Fly    54 -------------QSPQI------------VCGDIHGQFEDLLHLLELGG-SVQEHRYLFLGDLV 92
                         |.|.:            :|||:||:.:|||.:....| ...|:.|:|.||.|
Zfish   156 VLQLLYETKKFLKQMPNVIYLSTSYAKEITICGDLHGRLDDLLLIFYKNGLPSAENPYIFNGDFV 220

  Fly    93 DRGKNSVETFLLLAALKVRHPAQVSLLRGNHECRSATRSYGFYEECLSRYGS--ANVWRMCCRVF 155
            ||||.|.|..::|.|..:.:|..:.|.|||||.......|||..|.:.:|.:  ..:.::...||
Zfish   221 DRGKKSTEIIIILFAFVLLYPDHMHLNRGNHEDHIMNLRYGFTREVMQKYKTHGREILQLLQDVF 285

  Fly   156 DLLPLAAIIDGNILCVHGGLSPDMQRLDDLRSLDR------------------------------ 190
            .|||:|.:||..:|.||||:| |...||.|.:::|
Zfish   286 SLLPVATVIDNKVLIVHGGIS-DKTDLDFLSTVERHKVKSALRLPKRSTDHLTVRSCSRSSSRNR 349

  Fly   191 ---------------------------------------CH------------------------ 192
                                                   |.
Zfish   350 GRNSRSSSRHSSRSRRKKLSKQGSRSSSSSSSSSSSSSMCSPRVSAKNTPRRPPPSPTDMLQVPF 414

  Fly   193 ----------EIPESGI----IADLLWSDPQEAPGWAASP---RGHGKLFGGDVVEEFTRANGIS 240
                      |:|...:    :.|:|||||:...|  .||   ||.|..||.||.:...:.:|:.
Zfish   415 LDSFVSLEPPELPREELEWQQVVDILWSDPKHQNG--CSPNSFRGGGCYFGPDVTQTLLQKHGLC 477

  Fly   241 LICRAHQLAQDGFR-WHFGQLLVTIWSAPNYCYRCGNKAAILRL 283
            |:.|:|:..|:|:. .|.|| ::||:||.||.....|:.|.::|
Zfish   478 LLIRSHECKQEGYELCHNGQ-VITIFSASNYYEEGSNRGAYVKL 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11597	NP_001036602.1	PTZ00239	12..307	CDD:173488	104/423 (25%)
CG11597	NP_001036602.1	MPP_superfamily	12..296	CDD:301300	104/423 (25%)
ppef1	XP_021335306.1	IQ	32..54	CDD:197470
		MPP_RdgC	132..532	CDD:277364	100/396 (25%)
		EFh_PEF	567..715	CDD:330173
		EF-hand motif	567..600	CDD:320054
		EF-hand motif	609..649	CDD:320054
		EFh	650..716	CDD:238008
		EF-hand motif	650..683	CDD:320054
		EF-hand motif	690..719	CDD:320054
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810