Protein Alignment CG11597 and PPP2CB

DIOPT Version :10

• Sequence 1: NP_648513.3
• Gene: CG11597 / 39337
• FlyBaseID: FBgn0036212
• Length: 317
• Species: Drosophila melanogaster
• Sequence 2: NP_001009552.1
• Gene: PPP2CB / 5516
• HGNCID: 9300
• Length: 309
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 150/313 - (47%)
• Similarity: 201/313 - (64%)
• Gaps: 23/313 - (7%)

  Fly     8 EAMNDADRLVENLRHVPVRLPRELEVRQLCRSLSDLLVGESNLLSLQSPQIVCGDIHGQFEDLLH 72
            |.:|:..:|.||            :||.||....::|..|||:..::.|..||||:||||.||:.
Human    15 EQLNECKQLNEN------------QVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLME 67

  Fly    73 LLELGGSVQEHRYLFLGDLVDRGKNSVETFLLLAALKVRHPAQVSLLRGNHECRSATRSYGFYEE 137
            |..:||...:..|||:||.||||..||||..||.|||||:|.::::||||||.|..|:.||||:|
Human    68 LFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDE 132

  Fly   138 CLSRYGSANVWRMCCRVFDLLPLAAIIDGNILCVHGGLSPDMQRLDDLRSLDRCHEIPESGIIAD 202
            ||.:||:||||:....:||.|||.|::||.|.|:||||||.:..||.:|:|||..|:|..|.:.|
Human   133 CLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCD 197

  Fly   203 LLWSDPQEAPGWAASPRGHGKLFGGDVVEEFTRANGISLICRAHQLAQDGFRWHFGQLLVTIWSA 267
            ||||||.:..||..||||.|..||.|:.|.|..|||::|:.|||||..:|:.|...:.:|||:||
Human   198 LLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSA 262

  Fly   268 PNYCYRCGNKAAILRLNAAGDYDFKVFEAQALHSKPQPRKPK----KRCRQFF 316
            |||||||||:|||:.|:....|.|..|:       |.||:.:    :|...:|
Human   263 PNYCYRCGNQAAIMELDDTLKYSFLQFD-------PAPRRGEPHVTRRTPDYF 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11597	NP_648513.3	MPP_superfamily	12..296	CDD:472684	143/283 (51%)
PPP2CB	NP_001009552.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	146/296 (49%)