DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11597 and PPP2CB

DIOPT Version :9

Sequence 1:NP_001036602.1 Gene:CG11597 / 39337 FlyBaseID:FBgn0036212 Length:317 Species:Drosophila melanogaster
Sequence 2:NP_001009552.1 Gene:PPP2CB / 5516 HGNCID:9300 Length:309 Species:Homo sapiens


Alignment Length:313 Identity:150/313 - (47%)
Similarity:201/313 - (64%) Gaps:23/313 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 EAMNDADRLVENLRHVPVRLPRELEVRQLCRSLSDLLVGESNLLSLQSPQIVCGDIHGQFEDLLH 72
            |.:|:..:|.||            :||.||....::|..|||:..::.|..||||:||||.||:.
Human    15 EQLNECKQLNEN------------QVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLME 67

  Fly    73 LLELGGSVQEHRYLFLGDLVDRGKNSVETFLLLAALKVRHPAQVSLLRGNHECRSATRSYGFYEE 137
            |..:||...:..|||:||.||||..||||..||.|||||:|.::::||||||.|..|:.||||:|
Human    68 LFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDE 132

  Fly   138 CLSRYGSANVWRMCCRVFDLLPLAAIIDGNILCVHGGLSPDMQRLDDLRSLDRCHEIPESGIIAD 202
            ||.:||:||||:....:||.|||.|::||.|.|:||||||.:..||.:|:|||..|:|..|.:.|
Human   133 CLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCD 197

  Fly   203 LLWSDPQEAPGWAASPRGHGKLFGGDVVEEFTRANGISLICRAHQLAQDGFRWHFGQLLVTIWSA 267
            ||||||.:..||..||||.|..||.|:.|.|..|||::|:.|||||..:|:.|...:.:|||:||
Human   198 LLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSA 262

  Fly   268 PNYCYRCGNKAAILRLNAAGDYDFKVFEAQALHSKPQPRKPK----KRCRQFF 316
            |||||||||:|||:.|:....|.|..|:       |.||:.:    :|...:|
Human   263 PNYCYRCGNQAAIMELDDTLKYSFLQFD-------PAPRRGEPHVTRRTPDYF 308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11597NP_001036602.1 PTZ00239 12..307 CDD:173488 145/294 (49%)
MPP_superfamily 12..296 CDD:301300 143/283 (51%)
PPP2CBNP_001009552.1 MPP_PP2A_PP4_PP6 9..293 CDD:277360 146/296 (49%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0639
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53795
OrthoDB 1 1.010 - - D349967at33208
OrthoFinder 1 1.000 - - FOG0000018
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
65.790

Return to query results.
Submit another query.