DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11597 and PpD3

DIOPT Version :9

Sequence 1:	NP_001036602.1	Gene:	CG11597 / 39337	FlyBaseID:	FBgn0036212	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_001262433.1	Gene:	PpD3 / 49779	FlyBaseID:	FBgn0005777	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	280	Identity:	107/280 - (38%)
Similarity:	155/280 - (55%)	Gaps:	13/280 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RLPRELEVRQLCRSLSDLLVGESNLLSLQSPQ----IVCGDIHGQFEDLLHLLELGGSVQE-HRY 85
            ||.|:...:.|| .:...:..:.:|:.:..|.    .:||||||||.||:::.|:.|...| :.|
  Fly   225 RLHRKFAYKILC-EIDTYMRAQPSLVDITVPDEEKFTICGDIHGQFYDLMNIFEINGLPSEKNPY 288

  Fly    86 LFLGDLVDRGKNSVETFLLLAALKVRHPAQVSLLRGNHECRSATRSYGFYEECLSRYGSANVWRM 150
            ||.||.||||..|||....|...|:.:|....|.|||||..:..:.|||..|..::|.|| :..:
  Fly   289 LFNGDFVDRGSFSVECIFTLFGFKLLYPNHFFLARGNHESINMNQMYGFTGEVTAKYTSA-MADI 352

  Fly   151 CCRVFDLLPLAAIIDGNILCVHGGL-SPDMQRLDDLRSLDRCHEIPESGIIADLLWSDPQEAPGW 214
            ..:||:.|||...|:..||.:|||| |.:...||.:|.::|..:.||.|::.:|||||||:..|.
  Fly   353 FTQVFNWLPLCHCINQKILVMHGGLFSTEDVTLDHIRRIERNCQPPEEGLMCELLWSDPQQWMGL 417

  Fly   215 AASPRGHGKLFGGDVVEEFTRANGISLICRAHQLAQDGFRWHFGQLLVTIWSAPNYCYRCGNKAA 279
            ..|.||.|..||.||.|:|.:.|.:..|.|:|::...|:........:|::||||||...||..|
  Fly   418 GQSKRGVGIQFGPDVTEKFCKDNNLDYIIRSHEVKDMGYEVAHNGKCITVFSAPNYCDTMGNMGA 482

  Fly   280 ILRL---NAAGDYDFKVFEA 296
            .:.:   |...:|  |.|||
  Fly   483 FITITGNNLKPNY--KSFEA 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11597	NP_001036602.1	PTZ00239	12..307	CDD:173488	107/280 (38%)
CG11597	NP_001036602.1	MPP_superfamily	12..296	CDD:301300	105/278 (38%)
PpD3	NP_001262433.1	TPR_11	49..114	CDD:290150
		TPR_1	49..81	CDD:278916
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		MPP_PP5_C	198..513	CDD:277362	107/280 (38%)
		PP2Ac	226..502	CDD:197547	106/279 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438822
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740