DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11597 and rdgC

DIOPT Version :9

Sequence 1:	NP_001036602.1	Gene:	CG11597 / 39337	FlyBaseID:	FBgn0036212	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	NP_536738.3	Gene:	rdgC / 40224	FlyBaseID:	FBgn0265959	Length:	746	Species:	Drosophila melanogaster

Alignment Length:	324	Identity:	106/324 - (32%)
Similarity:	154/324 - (47%)	Gaps:	52/324 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 MNDADRLVENLRHV-------PVRL-------------------PR--ELEVRQLCRSLSDLLVG 46
            ::|.|.|||....:       |:|.                   |:  .|.:|:..:||.. |..
  Fly   163 LDDKDDLVEEFGDIVNAKIELPIRKNHIDLLIDVFRKKRGNRLHPKYVALILREAAKSLKQ-LPN 226

  Fly    47 ESNLLSLQSPQI-VCGDIHGQFEDLLHLLELGG-SVQEHRYLFLGDLVDRGKNSVETFLLLAALK 109
            .|.:.:..|.|: ||||:||:.:|||.:|...| ....:.|:|.||.|||||..:|..|||.:|.
  Fly   227 ISPVSTAVSQQVTVCGDLHGKLDDLLVVLHKNGLPSSSNPYVFNGDFVDRGKRGLEVLLLLLSLY 291

  Fly   110 VRHPAQVSLLRGNHECRSATRSYGFYEECLSRY--GSANVWRMCCRVFDLLPLAAIIDGNILCVH 172
            :..|..|.|.|||||.......|||..|..|:|  ....:......|:..|||.::::..:|.||
  Fly   292 LAFPNAVFLNRGNHEDSVMNARYGFIREVESKYPRNHKRILAFIDEVYRWLPLGSVLNSRVLIVH 356

  Fly   173 GGLSPDMQRLDDLRSLDRCHEI---------------PESGIIADLLWSDPQEAPGWAASP-RGH 221
            ||.| |...||.::|:||...:               .|...|.|::|||||...|...:. ||.
  Fly   357 GGFS-DSTSLDLIKSIDRGKYVSILRPPLTDGEPLDKTEWQQIFDIMWSDPQATMGCVPNTLRGA 420

  Fly   222 GKLFGGDVVEEFTRANGISLICRAHQLAQDGFRWHFGQLLVTIWSAPNYCYRCG-NKAAILRLN 284
            |..||.||.:.|.:.:.:|.:.|:|:...:|..:.....::||:||.|| |..| ||.|.:|||
  Fly   421 GVWFGPDVTDNFLQRHRLSYVIRSHECKPNGHEFMHDNKIITIFSASNY-YAIGSNKGAYIRLN 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11597	NP_001036602.1	PTZ00239	12..307	CDD:173488	106/322 (33%)
CG11597	NP_001036602.1	MPP_superfamily	12..296	CDD:301300	106/322 (33%)
rdgC	NP_536738.3	IQ	89..111	CDD:197470
		MPP_RdgC	184..494	CDD:277364	101/303 (33%)
		EFh	616..681	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438797
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840