DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11597 and Ppef1

DIOPT Version :9

Sequence 1:	NP_001036602.1	Gene:	CG11597 / 39337	FlyBaseID:	FBgn0036212	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	XP_038955765.1	Gene:	Ppef1 / 317498	RGDID:	1562772	Length:	664	Species:	Rattus norvegicus

Alignment Length:	322	Identity:	91/322 - (28%)
Similarity:	154/322 - (47%)	Gaps:	50/322 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PEAMNDADRLVENLR-----HVPVRLPRELEVRQLCRSLSDLLVGESNLLSLQSPQI-VCGDIHG 65
            |....|.:.|::..:     |....|....|.|::.:.:.:.    :.:.:..:.:| :|||:||
  Rat   140 PLTFTDINLLLQAFKQQQTLHAHYVLEVLFEARKILKQMPNF----TRIQTFPAKEITICGDLHG 200

  Fly    66 QFEDLLHLLELGGSVQE-HRYLFLGDLVDRGKNSVETFLLLAALKVRHPAQVSLLRGNHECRSAT 129
            :.:||:.:....|...| :.|:|.||.||||.||:|..::|....:.:|..:.|.|||||.....
  Rat   201 KLDDLMLIFYKNGLPSEKNPYVFNGDFVDRGNNSMEILMILLVSFLVYPTDLHLNRGNHEDFMMN 265

  Fly   130 RSYGFYEECLSRY--GSANVWRMCCRVFDLLPLAAIIDGNILCVHGGLSPDMQRLDDLRSLDR-- 190
            ..|||.:|.|.:|  ....:.::...::..||:..|||..||.:|||:| :...|:.|:.|.|
  Rat   266 LRYGFTKEILQKYKLHGKKILQVLEELYTWLPIGTIIDNEILVIHGGIS-ESTDLNILQQLQRNK 329

  Fly   191 --------------CH-EIPESG----------------IIADLLWSDPQEAPG-WAASPRGHGK 223
                          |: :..::|                .|.|||||||:...| :..:.||.|.
  Rat   330 MKSVLMPPMSTNQECNIKKNKAGPSEQSASEQLTKLEWEQIIDLLWSDPRGKKGCYPNTSRGGGC 394

  Fly   224 LFGGDVVEEFTRANGISLICRAHQLAQDGFR-WHFGQLLVTIWSAPNYCYRCGNKAAILRLN 284
            .||.||..:....|.:.::.|:|:...||:. .|.|: ::|::||.||.....|:.|.:||:
  Rat   395 YFGPDVTSKVLNKNQLKMVIRSHECKPDGYEICHDGK-VITVFSASNYYEEGSNRGAYIRLS 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11597	NP_001036602.1	PTZ00239	12..307	CDD:173488	90/317 (28%)
CG11597	NP_001036602.1	MPP_superfamily	12..296	CDD:301300	90/317 (28%)
Ppef1	XP_038955765.1	IQ	40..>57	CDD:197470
		MPP_RdgC	140..466	CDD:277364	91/322 (28%)
		PTZ00183	505..647	CDD:185503
		EF-hand_7	582..650	CDD:404394
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810