DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11597 and Ppef1

DIOPT Version :9

Sequence 1:	NP_001036602.1	Gene:	CG11597 / 39337	FlyBaseID:	FBgn0036212	Length:	317	Species:	Drosophila melanogaster
Sequence 2:	XP_011246120.1	Gene:	Ppef1 / 237178	MGIID:	1097157	Length:	676	Species:	Mus musculus

Alignment Length:	314	Identity:	86/314 - (27%)
Similarity:	144/314 - (45%)	Gaps:	52/314 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 ENLRHVPVRLPRELEVRQLCRSLSDLLVGESNLLSLQSPQI-VCGDIHGQFEDLLHLLELGGSVQ 81
            :.:.|....|....|.|::.:.:.:.    |::.:..:.:| :|||:||:.:||:.:....|...
Mouse   160 QQILHAHYVLEVLFEARKVLKQMPNF----SHVKTFPAKEITICGDLHGKLDDLMLIFYKNGLPS 220

  Fly    82 EHR-YLFLGDLVDRGKNSVETFLLLAALKVRHPAQVSLLRGNHECRSATRSYGFYEECLSRY--G 143
            |:. |:|.||.||||.||:|..::|....:.:|:.:.|.|||||.......|||.:|.|.:|  .
Mouse   221 ENNPYVFNGDFVDRGNNSMEILMILLVCFLVYPSDLHLNRGNHEDFMMNLRYGFTKEILQKYKLH 285

  Fly   144 SANVWRMCCRVFDLLPLAAIIDGNILCVHGGLSPDMQRLDDLRSLDR------------------ 190
            ...:.::...|:..||:..|||..||.:|||:| :...|:.|..|.|
Mouse   286 GRKILQVLEEVYTWLPIGTIIDNEILVIHGGIS-ESTDLNTLHQLQRNKMKSVLMPPVLGNQETG 349

  Fly   191 -----------------CHEIPESGI-------IADLLWSDPQEAPG-WAASPRGHGKLFGGDVV 230
                             ..:.|...:       |.|:|||||:...| :..:.||.|..||.||.
Mouse   350 EKRNKSASNYVEPRKVEPDKTPSEDLTKQEWEQIVDILWSDPRGKKGCYPNTSRGGGCYFGPDVT 414

  Fly   231 EEFTRANGISLICRAHQLAQDGFRWHFGQLLVTIWSAPNYCYRCGNKAAILRLN 284
            .:....|.:.::.|:|:...||:.......::|::||.||.....|:.|.:||:
Mouse   415 SKVLSKNQLKMLIRSHECKPDGYEVSHDGKVITVFSASNYYEEGSNRGAYIRLS 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11597	NP_001036602.1	PTZ00239	12..307	CDD:173488	86/314 (27%)
CG11597	NP_001036602.1	MPP_superfamily	12..296	CDD:301300	86/314 (27%)
Ppef1	XP_011246120.1	MPP_RdgC	144..479	CDD:277364	86/314 (27%)
		PTZ00183	518..660	CDD:185503
		EF-hand_7	595..663	CDD:372618
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810