DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5946 and NIA2

DIOPT Version :9

Sequence 1:	NP_001287035.1	Gene:	CG5946 / 39336	FlyBaseID:	FBgn0036211	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_174901.1	Gene:	NIA2 / 840630	AraportID:	AT1G37130	Length:	917	Species:	Arabidopsis thaliana

Alignment Length:	281	Identity:	121/281 - (43%)
Similarity:	188/281 - (66%)	Gaps:	24/281 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 LVDPNDKYLLPLIEKENLSHDTRRFRFGLPSKQHVLGLPVGQHIHLIATIDNELIIRPYTPISSD 114
            ||:|..|..:.|:||.::|||.|:|||.||.:..|||||||:||.|.|||:::|.:|.|||.|:.
plant   656 LVNPRAKVPVQLVEKTSISHDVRKFRFALPVEDMVLGLPVGKHIFLCATINDKLCLRAYTPSSTV 720

  Fly   115 EDVGYVDLVVKVYFKDSHPKFPAGGKMTQHLEQLELGDKISFRGPSGRLQYLGNGTFSIKKLRKD 179
            :.|||.:||||:||...||:||.||.|:|:|:.|.:|..:..:||.|.::|||.|:|::    ..
plant   721 DVVGYFELVVKIYFGGVHPRFPNGGLMSQYLDSLPIGSTLEIKGPLGHVEYLGKGSFTV----HG 781

  Fly   180 PPKHVTAKRVNMIAGGTGITPMLQLAREVLKRSDKDKTELALLFANQSEKDILLRAELDELAQKH 244
            .||.  |.::.|:||||||||:.|:.:.:|| ..:|:||:.:::||::|:|||||.|||..|:::
plant   782 KPKF--ADKLAMLAGGTGITPVYQIIQAILK-DPEDETEMYVIYANRTEEDILLREELDGWAEQY 843

  Fly   245 PDQFKIWYTVDKANEAIKRMPRMGNARFVAWSYNTGHVNDDMMQQHLYPPGED--TLCLLCGPPP 307
            ||:.|:||.|:.|.|              .|:|:||.:::.:|::|: |.|.|  .|.:.|||||
plant   844 PDRLKVWYVVESAKE--------------GWAYSTGFISEAIMREHI-PDGLDGSALAMACGPPP 893

  Fly   308 MVNYTCIPGLERLGHRAEQRF 328
            |:.:...|.||::.:..::.|
plant   894 MIQFAVQPNLEKMQYNIKEDF 914

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5946	NP_001287035.1	PTZ00319	51..330	CDD:173521	120/280 (43%)
CG5946	NP_001287035.1	cyt_b5_reduct_like	59..330	CDD:99780	117/272 (43%)
NIA2	NP_174901.1	PLN02252	1..917	CDD:215141	121/281 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	131	1.000	Domainoid score	I1683
eggNOG	1	0.900	-	-		E1_COG0543
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000472
OrthoInspector	1	1.000	-	-		otm2816
orthoMCL	1	0.900	-	-		OOG6_100179
Panther	1	1.100	-	-	LDO	PTHR19370
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X606
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.770