DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5946 and cyb5r4

DIOPT Version :9

Sequence 1:	NP_001287035.1	Gene:	CG5946 / 39336	FlyBaseID:	FBgn0036211	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_005173509.1	Gene:	cyb5r4 / 553685	ZFINID:	ZDB-GENE-050522-225	Length:	577	Species:	Danio rerio

Alignment Length:	274	Identity:	78/274 - (28%)
Similarity:	135/274 - (49%)	Gaps:	61/274 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 TLVDPNDKYLL----PLIEKENLSHDTRRFRFGLP--SKQHVLGLPVGQHIHLIATIDNELIIRP 107
            |.:...|:.|.    .|:.|.:::|:|:..|..||  |:..|   |||:|::|..::....:::|
Zfish   322 TFIQCKDRGLFYRECVLLSKTDVTHNTQLLRLQLPPGSRMQV---PVGRHVYLKTSVQGTDVVKP 383

  Fly   108 YT--------PISSDEDVGY-VDLVVKVYFKDSHPKFPAGGKMTQHLEQLELGDKISFRGPSGRL 163
            ||        |..|..:||. :.|::|||         ..|.:|.|:..|.:|..:|..||.|.|
Zfish   384 YTAVDQMLIPPSQSSAEVGSDIHLMIKVY---------PDGVLTPHIANLPIGASLSVGGPEGSL 439

  Fly   164 QYLGNGTFSIKKLRKDPPKHVTAKRVNMIAGGTGITPMLQLAREVLKRSDKDKTELALLFANQSE 228
                    :::.||     .||  .:.|:|.|||.|||.:|.|..|:.....: ::.|:|.|:.|
Zfish   440 --------TLRVLR-----DVT--HLYMLAAGTGFTPMARLIRLALQEFTVIR-KMKLMFFNRQE 488

  Fly   229 KDILLRAELDELAQKHPDQFKIWYTVDKANEAIKRMPRMGNARFVAWSYNTGHVNDDMMQQHLYP 293
            :|||.:::||||..|. ::|::.:.:.:..:              :|:...|.::..|:|..|..
Zfish   489 RDILWQSQLDELCTKE-ERFEVQHVLSEPAD--------------SWTGRRGRIDACMLQNFLER 538

  Fly   294 PGEDTLCL--LCGP 305
            | |::.||  :|||
Zfish   539 P-ENSKCLVCVCGP 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5946	NP_001287035.1	PTZ00319	51..330	CDD:173521	77/272 (28%)
CG5946	NP_001287035.1	cyt_b5_reduct_like	59..330	CDD:99780	75/264 (28%)
cyb5r4	XP_005173509.1	Cyt-b5	108..180	CDD:278597
		p23_NCB5OR	228..314	CDD:107240
		cyt_b5_reduct_like	336..575	CDD:99780	75/260 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0543
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1311668at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820