DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5946 and Cyb5r1

DIOPT Version :9

Sequence 1:	NP_001287035.1	Gene:	CG5946 / 39336	FlyBaseID:	FBgn0036211	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001013144.1	Gene:	Cyb5r1 / 304805	RGDID:	1306084	Length:	305	Species:	Rattus norvegicus

Alignment Length:	319	Identity:	162/319 - (50%)
Similarity:	218/319 - (68%)	Gaps:	26/319 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LAVGVVAVLAGALIVHYLLNKKSTKPRREPNRTARLRTLVDPNDKYLLPLIEKENLSHDTRRFRF 76
            |.||:. .|.|..:..||: ::|.:|:         .||.||::||||.|::|..:||:||||||
  Rat    13 LGVGLF-TLFGLALGTYLV-RRSRRPQ---------VTLQDPDEKYLLRLLDKTTVSHNTRRFRF 66

  Fly    77 GLPSKQHVLGLPVGQHIHLIATIDNELIIRPYTPISSDEDVGYVDLVVKVYFKDSHPKFPAGGKM 141
            .||:..|:||||||:|::|.|.||...:||||||::||||.||||||:|||.|..||||..||||
  Rat    67 ALPTAHHILGLPVGKHVYLSARIDGSQVIRPYTPVTSDEDQGYVDLVIKVYLKGVHPKFSEGGKM 131

  Fly   142 TQHLEQLELGDKISFRGPSGRLQYLGNGTFSIKKLRKDPPKHVTAKRVNMIAGGTGITPMLQLAR 206
            :|:|:.|::||.:.||||||.|.|.|.|.|:|:..:|.||:...||::.||||||||||||||.|
  Rat   132 SQYLDSLKIGDVVEFRGPSGLLSYAGKGNFNIQPNKKSPPELRVAKKLGMIAGGTGITPMLQLIR 196

  Fly   207 EVLKRSDKDKTELALLFANQSEKDILLRAELDELAQKHPDQFKIWYTVDKANEAIKRMPRMGNAR 271
            .:|| ..:|.|:..||||||:||||:||.:|:||..::|.:||:|:|:|...|
  Rat   197 AILK-VPEDPTQCFLLFANQTEKDIILREDLEELQAQYPIRFKLWFTLDYPPE------------ 248

  Fly   272 FVAWSYNTGHVNDDMMQQHLYPPGEDTLCLLCGPPPMVNYTCIPGLERLGHRAEQRFSY 330
              .|:|:.|.|..||:|:||..|.||.|.|||||||||...|.|.|::||:..:.||:|
  Rat   249 --DWTYSKGFVTADMIQEHLPAPAEDVLLLLCGPPPMVQLACHPNLDKLGYSQKMRFTY 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5946	NP_001287035.1	PTZ00319	51..330	CDD:173521	150/278 (54%)
CG5946	NP_001287035.1	cyt_b5_reduct_like	59..330	CDD:99780	145/270 (54%)
Cyb5r1	NP_001013144.1	PTZ00319	8..305	CDD:173521	161/317 (51%)
Cyb5r1	NP_001013144.1	cyt_b5_reduct_like	49..305	CDD:99780	145/270 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	140	1.000	Domainoid score	I4635
eggNOG	1	0.900	-	-		E1_COG0543
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	344	1.000	Inparanoid score	I2253
OMA	1	1.010	-	-		QHG54129
OrthoDB	1	1.010	-	-		D1311668at2759
OrthoFinder	1	1.000	-	-		FOG0000472
OrthoInspector	1	1.000	-	-		otm46255
orthoMCL	1	0.900	-	-		OOG6_100179
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X606
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.780