DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5946 and Cyb5r3

DIOPT Version :9

Sequence 1:	NP_001287035.1	Gene:	CG5946 / 39336	FlyBaseID:	FBgn0036211	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	XP_006242127.1	Gene:	Cyb5r3 / 25035	RGDID:	2502	Length:	307	Species:	Rattus norvegicus

Alignment Length:	288	Identity:	169/288 - (58%)
Similarity:	211/288 - (73%)	Gaps:	15/288 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 RTARLRTLVDPNDKYLLPLIEKENLSHDTRRFRFGLPSKQHVLGLPVGQHIHLIATIDNELIIRP 107
            |::...||.:|:.||.|.||:||.:|||||||||.|||.||:||||:||||:|...||..|:|||
  Rat    35 RSSPAITLENPDIKYPLRLIDKEIISHDTRRFRFALPSPQHILGLPIGQHIYLSTRIDGNLVIRP 99

  Fly   108 YTPISSDEDVGYVDLVVKVYFKDSHPKFPAGGKMTQHLEQLELGDKISFRGPSGRLQYLGNGTFS 172
            |||:|||:|.|:|||||||||||:||||||||||:|:||.:.:||.|.||||:|.|.|.|.|.|:
  Rat   100 YTPVSSDDDKGFVDLVVKVYFKDTHPKFPAGGKMSQYLENMNIGDTIEFRGPNGLLVYQGKGKFA 164

  Fly   173 IKKLRKDPPKHVTAKRVNMIAGGTGITPMLQLAREVLKRSDKDKTELALLFANQSEKDILLRAEL 237
            |:..:|..|...|.|.|.|||||||||||||:.|.||| ...|.|...||||||||||||||.||
  Rat   165 IRADKKSNPVVRTVKSVGMIAGGTGITPMLQVIRAVLK-DPNDHTVCYLLFANQSEKDILLRPEL 228

  Fly   238 DELAQKHPDQFKIWYTVDKANEAIKRMPRMGNARFVAWSYNTGHVNDDMMQQHLYPPGEDTLCLL 302
            :||..:|..:||:|||||||.:              ||.|:.|.||::|::.||.||||:||.|:
  Rat   229 EELRNEHSSRFKLWYTVDKAPD--------------AWDYSQGFVNEEMIRDHLPPPGEETLILM 279

  Fly   303 CGPPPMVNYTCIPGLERLGHRAEQRFSY 330
            ||||||:.:.|:|.|||:||..|:.|::
  Rat   280 CGPPPMIQFACLPNLERVGHPKERCFTF 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5946	NP_001287035.1	PTZ00319	51..330	CDD:173521	166/278 (60%)
CG5946	NP_001287035.1	cyt_b5_reduct_like	59..330	CDD:99780	163/270 (60%)
Cyb5r3	XP_006242127.1	PTZ00319	22..307	CDD:173521	169/286 (59%)
Cyb5r3	XP_006242127.1	cyt_b5_reduct_like	51..307	CDD:99780	163/270 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353933
Domainoid	1	1.000	167	1.000	Domainoid score	I3772
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	344	1.000	Inparanoid score	I2253
OMA	1	1.010	-	-		QHG54129
OrthoDB	1	1.010	-	-		D1311668at2759
OrthoFinder	1	1.000	-	-		FOG0000472
OrthoInspector	1	1.000	-	-		otm46255
orthoMCL	1	0.900	-	-		OOG6_100179
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X606
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.810