DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5946 and Y52B11A.3

DIOPT Version :9

Sequence 1:	NP_001287035.1	Gene:	CG5946 / 39336	FlyBaseID:	FBgn0036211	Length:	330	Species:	Drosophila melanogaster
Sequence 2:	NP_001379343.1	Gene:	Y52B11A.3 / 173002	WormBaseID:	WBGene00013123	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	304	Identity:	67/304 - (22%)
Similarity:	127/304 - (41%)	Gaps:	50/304 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LNKKSTKPRREPNRTARLRTLVDPNDKYLLPLIEKENLSHDTRRFRFGLPSKQH-VLGLPVGQHI 93
            :::...|.:|.|..|.....::|           :..|:|||..|...||  :| ...:|:|.|:
Worm   274 IDRSKCKIQRRPGVTYHTTEIID-----------RYRLNHDTLIFSLQLP--EHTTYRIPIGHHV 325

  Fly    94 HLIATIDNELIIRPYTPISSDEDVGYVDLVVKVYFKDSHPKFPAGGKMTQHLEQLELGDKISFRG 158
            .:.....|.::.|||||| |:.|...:|.::|:|         :.|..|..||.|::|.::....
Worm   326 SIKIRKGNSVLYRPYTPI-SNPDPQKIDFMIKIY---------SNGICTPSLENLKIGGELEISD 380

  Fly   159 PSGR---LQYLGNGTFSIKKLRKDPPKHVTAKRVNMIAGGTGITPMLQLAREVLKRSDKDKTELA 220
            |.|.   .::..|                 |:.:.::|.|:|||||:.:..:.:::::...:::.
Worm   381 PIGERNFAEWTEN-----------------AQELILLAAGSGITPMIDIMEKRIQKTENSNSKVY 428

  Fly   221 LLFANQSEKDILLRAELDELAQKHPDQFKIWYTVDKANEAI--KRMPRMGNARFVAWSYNTGHVN 283
            .|..|::|.|  |:....|...|...:...:|:..:.:|.|  |.:............|..|.|:
Worm   429 FLMFNKTEND--LQTGKPEENPKSTWKMADFYSKYRGDERIVMKNVLSASECPVETGEYFNGRVS 491

  Fly   284 DDMMQQHLYPPG-EDTLCLLCGPPPMVNYTCIPGLERLGHRAEQ 326
            .|::...:.... ......:|||...: ......||.|...::|
Worm   492 TDLLNSIISTSSTASRRAFICGPDGFI-LAAKTALESLNLHSDQ 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5946	NP_001287035.1	PTZ00319	51..330	CDD:173521	63/283 (22%)
CG5946	NP_001287035.1	cyt_b5_reduct_like	59..330	CDD:99780	62/275 (23%)
Y52B11A.3	NP_001379343.1	Cyt-b5	61..127	CDD:395121
Y52B11A.3	NP_001379343.1	cyt_b5_reduct_like	293..538	CDD:99780	63/285 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1311668at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920