Protein Alignment CG5946 and CYB5R3

DIOPT Version :9

• Sequence 1: NP_001287035.1
• Gene: CG5946 / 39336
• FlyBaseID: FBgn0036211
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_001165131.1
• Gene: CYB5R3 / 1727
• HGNCID: 2873
• Length: 334
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 164/282 - (58%)
• Similarity: 205/282 - (72%)
• Gaps: 15/282 - (5%)

  Fly    49 TLVDPNDKYLLPLIEKENLSHDTRRFRFGLPSKQHVLGLPVGQHIHLIATIDNELIIRPYTPISS 113
            ||..|:.||.|.||::|.:|||||||||.|||.||:|||||||||:|.|.||..|::||||||||
Human    68 TLESPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISS 132

  Fly   114 DEDVGYVDLVVKVYFKDSHPKFPAGGKMTQHLEQLELGDKISFRGPSGRLQYLGNGTFSIKKLRK 178
            |:|.|:||||:||||||:||||||||||:|:||.:::||.|.||||||.|.|.|.|.|:|:..:|
Human   133 DDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKK 197

  Fly   179 DPPKHVTAKRVNMIAGGTGITPMLQLAREVLKRSDKDKTELALLFANQSEKDILLRAELDELAQK 243
            ..|...|.|.|.|||||||||||||:.|.::|..| |.|...||||||:|||||||.||:||..|
Human   198 SNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPD-DHTVCHLLFANQTEKDILLRPELEELRNK 261

  Fly   244 HPDQFKIWYTVDKANEAIKRMPRMGNARFVAWSYNTGHVNDDMMQQHLYPPGEDTLCLLCGPPPM 308
            |..:||:|||:|:|.|              ||.|..|.||::|::.||.||.|:.|.|:||||||
Human   262 HSARFKLWYTLDRAPE--------------AWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPM 312

  Fly   309 VNYTCIPGLERLGHRAEQRFSY 330
            :.|.|:|.|:.:||..|:.|.:
Human   313 IQYACLPNLDHVGHPTERCFVF 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5946	NP_001287035.1	PTZ00319	51..330	CDD:173521	162/278 (58%)
		cyt_b5_reduct_like	59..330	CDD:99780	159/270 (59%)
CYB5R3	NP_001165131.1	PTZ00319	44..334	CDD:173521	164/280 (59%)
		cyt_b5_reduct_like	78..334	CDD:99780	159/270 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159868
Domainoid	1	1.000	170	1.000	Domainoid score	I3780
eggNOG	1	0.900	-	-		E1_COG0543
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	336	1.000	Inparanoid score	I2404
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54129
OrthoDB	1	1.010	-	-		D1311668at2759
OrthoFinder	1	1.000	-	-		FOG0000472
OrthoInspector	1	1.000	-	-		otm42109
orthoMCL	1	0.900	-	-		OOG6_100179
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2205
SonicParanoid	1	1.000	-	-		X606
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.740