DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14130 and Alkbh2

DIOPT Version :9

Sequence 1:	NP_648511.2	Gene:	CG14130 / 39335	FlyBaseID:	FBgn0036210	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_001346869.1	Gene:	Alkbh2 / 231642	MGIID:	2141032	Length:	239	Species:	Mus musculus

Alignment Length:	239	Identity:	46/239 - (19%)
Similarity:	84/239 - (35%)	Gaps:	67/239 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 VESNAIKANLTAYFGKWPETEQ--KEFRQHMRIITDFI----------SEPEEQQLHEEIEPYMS 74
            :.:..:..:.|..||| .|.::  :|..|.:...|..:          |.|.:|..:.:     :
Mouse    38 LRAEGLSCDYTVLFGK-AEADKIFRELEQEVEYFTGALAKVQVFGKWHSVPRKQATYGD-----A 96

  Fly    75 RLRYEFDHWDDAIHGFRETERKKWFPKNREILERVRQVAFD--GAVMPYVHILDLAPDGVIKPHV 137
            .|.|.|.       |...|. |.|.|    :|||||....:  |....:| :::...||.  .|:
Mouse    97 GLTYTFS-------GLTLTP-KPWVP----VLERVRDRVCEVTGQTFNFV-LVNRYKDGC--DHI 146

  Fly   138 DSTRYCGNTISGISLLSDSVMRLVRTDEQRYQQQSSGTATDPNSQGSEPDAAYRHQPEASLKNNF 202
            ...|                      |::|  :.:.|:.....|.|:..|..:||:.....:...
Mouse   147 GEHR----------------------DDER--ELAPGSPIASVSFGACRDFIFRHKDSRGKRPRR 187

  Fly   203 YADIL---LPRRSLYIMSHTARYKFTHEILAKEHSQFQGALVPR 243
            ..:::   |...||.:|:......:.|.:..::.     .|.||
Mouse   188 TVEVVRLQLAHGSLLMMNPPTNTHWYHSLPIRKR-----VLAPR 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14130	NP_648511.2	None
Alkbh2	NP_001346869.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	11..32
		2OG-FeII_Oxy_2	50..232	CDD:372627	45/227 (20%)
		Substrate binding. /evidence=ECO:0000250	80..82		0/1 (0%)
		Substrate binding. /evidence=ECO:0000250	100..102		1/1 (100%)
		Alpha-ketoglutarate binding. /evidence=ECO:0000250	137..139		0/1 (0%)
		Alpha-ketoglutarate binding. /evidence=ECO:0000250	226..232		1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3145
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900