DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42255 and Cubn

DIOPT Version :9

Sequence 1:	NP_729748.3	Gene:	CG42255 / 39334	FlyBaseID:	FBgn0259140	Length:	3613	Species:	Drosophila melanogaster
Sequence 2:	NP_001074553.1	Gene:	Cubn / 65969	MGIID:	1931256	Length:	3623	Species:	Mus musculus

Alignment Length:	3904	Identity:	1048/3904 - (26%)
Similarity:	1682/3904 - (43%)	Gaps:	625/3904 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LFLLVFCLQFP----HSNTSRDNLEKR---AHLVRQSND--NLLLEPAWDRNVSLRLMGESATVT 64
            |:..|..|..|    .:.|....|:||   .|..|.:.:  ||:...:..:|:..| .|....:.
Mouse     6 LWGFVTLLMVPGLDGETGTPEQKLQKRIADLHQPRMTTEEGNLVFLTSSAQNIEFR-TGSLGKIK 69

  Fly    65 INDVDMMTVLRRRQRIIADRQAARREPLKVDAVRDMFHDVELKMTRIQRRIFSARNSTKRSGLNQ 129
            :||.|:...|.:.||             ..|.:      ::||           ||:|   ||.|
Mouse    70 LNDDDLGECLHQIQR-------------NKDDI------IDLK-----------RNTT---GLPQ 101

  Fly   130 RILRRQLQRVERVKGI---LQTLAGNLARNECLSNPCKNGGTCHDAYKGFQCECPAGWQGDSCED 191
            .||.:..|...::..:   .|:|..|:.|..|.||||.|||||.:.:..|.|.||:.|:|..|.:
Mouse   102 NILSQVHQLNSKLVDLERDFQSLQQNVERKVCSSNPCHNGGTCVNLHDSFICICPSQWKGLFCSE 166

  Fly   192 DVNECFTLAGTDLDGCLNNGQCINTPGSYRCVCRNGFTGTHCRLRHNTCLFGGSRELCGEHGTC- 255
            |||||...|||.. ||.:...|:||.||:||.|.....|..|..::|.| ..||::|| :||.|
Mouse   167 DVNECVLYAGTPF-GCQSGSTCVNTMGSFRCDCTPDTYGPQCASKYNDC-EQGSQQLC-KHGICE 228

  Fly   256 -IQAA--NSAGYVCICDQGWTWADANVTSASPSACVRDVDECEPRVNPC--HDECINLPGSFRCG 315
             :|..  ....:.||||.|||      |..:..:|..|.|||..:.:||  |.:|.|..|||.||
Mouse   229 DLQRVYHGQLRFNCICDAGWT------TLPNGISCTEDKDECSLQPSPCSEHAQCFNTQGSFYCG 287

  Fly   316 ACPTGYTGDGRFCRDIDECASEDNGGCSLQPRVTCTNTEGSHRCGRCPAGWTGDGRTCTASDSNS 380
            |||.|:.|:|..|:||:|| ..:|||||..|.|.|.||.||..||.||||::||||.||..|..|
Mouse   288 ACPKGWQGNGYQCQDINEC-EINNGGCSQAPLVPCLNTPGSFTCGNCPAGFSGDGRVCTPLDICS 351

  Fly   381 CNNEGICHPLAKCEYVSD----MVVCTCPLGSFGHGYGADGCSADSSRLPCDQHPCQNNGTCVQN 441
            .:|.| |||.|.|...|.    :.|||||.|..|:|||::||...|:.  |.:|||. ||.|::.
Mouse   352 IHNGG-CHPDATCSSSSVLGSLLPVCTCPPGYTGNGYGSNGCVRLSNM--CSRHPCV-NGQCIET 412

  Fly   442 GRGTTCICQPGYSGVVCNSS-DACHPSPCLNGGTCRLLPDA--KYQCVCPRGYTGTTCSHQRFFC 503
            .....|.|..|:.|..|..: :.|..:||||||||   .|.  .:.|.|...:||..|...:..|
Mouse   413 VSSYFCKCDSGWFGQNCTENINECVSNPCLNGGTC---IDGVNGFTCDCTSSWTGYYCQTPQAAC 474

  Fly   504 GVTIRGPSGQLHY-PPNTADGDYQADERCPFIIRTNRNMVLNLTFTQFQLEDSADCTADFLQLHD 567
            |..:.|..|...| .||..   |..:..|.:::||:...||::|||.|.||.:::|..::||:||
Mouse   475 GGILSGTQGTFAYQSPNDT---YVHNVNCFWVVRTDEEKVLHITFTFFDLESASNCPREYLQIHD 536

  Fly   568 GNSLSSRLIGRFCGSRLPMTNGSVITTQEQVFFWFRSDNQTQGKGFHVIWNSLPFSCGETINLTS 632
            |:|.:...:||:|||..|.   .|.::...::|...|:...:|:||...|.:....||   .:.:
Mouse   537 GDSSADFPLGRYCGSTPPQ---GVHSSANSLYFHLYSEYIKRGRGFTARWEAKLPECG---GILT 595

  Fly   633 TQTGVLRSPGYPGQARPELDCRWQLTAPFGYRLLLRFYDISLGSSEASAGNCSQDSLIVYDS--- 694
            ...|.:.||||||...|..||.|.|....|..:...|..:||    .|..:||:|.|.:.|.
Mouse   596 GNYGSITSPGYPGNYPPGRDCVWNLLVSPGSLITFTFGTLSL----ESHNDCSKDYLEIRDGPFH 656

  Fly   695 -DRQLLRACQSIQPPPVYSSSNSLRLDFHTDAIRSDSSFQMHYEVVPGHPGCGGVYTESRGRI-- 756
             |..|.:.|.|:..||:.::..:.|:.||:|:..||..|.:.|...|....|||.||::.|.:
Mouse   657 HDPILGKFCTSLSTPPLQTTGPAARIHFHSDSETSDKGFHITYLTTPSDLYCGGNYTDTEGELLL 721

  Fly   757 ----SGYMNFEVCLYLIEQPRGTQVKLVIDRVSLVQSLSCHYLKIEIFDGRSTDAPLLRRICGSH 817
                ..:.:...|:|||.||:|.|:.:....|.|.....|.:..||:.|..|    |||:|||:
Mouse   722 PPLTGPFSHSRQCVYLISQPQGEQIVINFTHVELESQRGCSHTFIEVGDHES----LLRKICGN- 781

  Fly   818 EESELEPIISIGNVILVRYEYALSGVRLSKSFDLTYTRVCTGNFNTNSGIISTPNYPGPYFDDMT 882
              ..|.||.||.|.:.:|..  :..:....||...|...|.|... ..|:|.:|.||..|....|
Mouse   782 --ETLFPIRSISNNVWIRLR--IDALVQKASFRADYQVACGGELR-GEGVIRSPFYPNAYAGRRT 841

  Fly   883 CTYNLTGPLDTAVRMRITDLSLGTANNENDTSYLDVYLSA------DQK------RHIVKSTDNL 935
            |.:.::.|....|.:..||..:|:::: .||.|:::..|:      ::|      ...:.|..|:
Mouse   842 CRWTISQPPREVVLLNFTDFQIGSSSS-CDTDYIEIGPSSVLGSPGNEKFCGTNIPSFITSVYNV 905

  Fly   936 ILLSHSNRASLVFHGSGGGRGMRLEYNFVPNQCG-------GFLNEPGRRYVTAVRGTFCQWFID 993
            :.::....:|:      ..||....::....:||       |.:..||...|.. .|..|.|.|.
Mouse   906 LYVTFVKSSSM------ENRGFMAMFSSEKLECGKVLTESTGIIESPGHPNVYP-SGVNCTWHIV 963

  Fly   994 FPGRKKISI---------HTLGPTPSISIYDN--STSPGKL--------VNSYSGSVGDVFDGDL 1039
            ....:.|.:         |.......:.:||.  .||.|:.        :.|.|.|:..:|..|.
Mouse   964 VQRGQLIRLVFSSFYLEFHYNCANDYLEVYDTIAQTSLGRYCGKSIPPSLTSSSHSIKLIFVSDS 1028

  Fly  1040 LTINLHTNWPRLEIYSIQFDIVQQDS-CGGTFTARFGYIKSPNWPKNYGESQMCEWILRAPFGHR 1103
            ...:        |.:||.::.:...| |...:|..||.:.|||:|.||..:..|.:.:......:
Mouse  1029 ALAH--------EGFSINYEAINASSVCLYDYTDNFGRLSSPNFPNNYPHNWNCVYRITVGLNQQ 1085

  Fly  1104 IELVVHNFTLEEEYSSTGCWTDWLEIRNGDSESSPLIGRYCGNEIPSRIPSFGNVLHLKFKSDDS 1168
            |.|...:|.| |:|....| .|::|||:|..|:|||||.|||:..|.||.|..|.|.|:||||.:
Mouse  1086 IALHFTDFAL-EDYFGPKC-VDFVEIRDGGFETSPLIGIYCGSVFPPRIISHSNKLWLRFKSDTA 1148

  Fly  1169 MEEKGFLLSWQQMGAGCGGKLSSSMGTIHSPHLLAGNRGILACDWQIIVAEGSRVSLQ-----LR 1228
            :..:||...|.....||||.|::..|.:.||:..........|.|::..:.||...|:     |.
Mouse  1149 LTARGFSAYWDASSTGCGGNLTTPTGVLTSPNYPMPYYHSSECYWRLEASRGSPFLLEFQDFHLE 1213

  Fly  1229 SNDNRICS-GQLTLYDGPTTASNPIVIRCNGTIAKPLQSTGNRVL--VRYDVGHDAPDGTDFMLN 1290
            .:.|  || ..|.::|||:|.|..|...|..|...|::|:.:.||  :|.|.|.   .|..|.:|
Mouse  1214 HHPN--CSLDYLAVFDGPSTNSRLINKLCGDTPPAPIRSSKDIVLLKLRTDAGQ---QGRGFEIN 1273

  Fly  1291 YQTNCR--VRLEGLQGAIETPNFPENYPPGQDCEWDIRA--GGRKNHLQLIFSHLSVEKFSSICL 1351
            |:..|.  |.:....|.:|:.|:|..|...|.|.|.|:|  |...|:   .|....||.:.: |.
Mouse  1274 YRQTCDNVVIVNKTSGILESINYPNPYDKDQRCNWTIQATTGNTVNY---TFLEFDVENYVN-CS 1334

  Fly  1352 NDYVSLVDMLDDQTLSEQHLCTNDGLEPITTVGNRLLLRFKSD--SSVELQGFRAEYKRIGCGEH 1414
            .||:.|.|  ..|.:.  ..|..:...|..|.|::|::.|.:|  .|.| :||:..:...|||..
Mouse  1335 TDYLELYD--GPQRIG--RYCGENIPPPGATTGSKLIVVFHTDGVDSGE-KGFKMHWFIHGCGGE 1394

  Fly  1415 LRESGGRFESPNAPFSV--DMDCVWIITASEGNQIRLLLH---------------EVY----FEA 1458
            :..:.|.|.||..|.|.  :.:|:|.|..:.||.|:|.:|               |:|    |.:
Mouse  1395 MSGTMGSFSSPGYPNSYPHNKECIWNIRVAPGNSIQLTIHDFDVEYHASCKYDTLEIYTGLDFHS 1459

  Fly  1459 PQIECRDAESSLSVSAPSGYNSSVVLFRSCHEETQTQTFTSPGNELVIRFVSSSAPSRKYFKASF 1523
            |:|      :.|...:||               ......:|..|||.|||.:.|:.:.:.|.||:
Mouse  1460 PRI------AQLCSRSPS---------------ANPMQISSTDNELAIRFKTDSSLNGRGFNASW 1503

  Fly  1524 VQVPASCGGYISASSGVLTTPGFHNHQDSKNVANYTSNIECVWTVEVTNGYGIRPHFEQFNLTDS 1588
            ..||..|||....|.|.:.:|.:.|        ||.:|.||.|.::|...:.:..:...|:|..:
Mouse  1504 RAVPGGCGGIFQVSRGEIHSPNYPN--------NYRANTECSWIIQVEKYHRVLLNITDFDLEAT 1560

  Fly  1589 GNCSVSFVELTKLEPDNKEIFLEKTCGEDSPMIRIV-HGRKLRVRFKSQAGTWGR-FIMYFERQC 1651
            .:|.:::...:..   |..:  ...||...|...|. .|..|.|||:|.:.:..| |...|.::|
Mouse  1561 DSCLMTYDGSSSA---NTRV--ATVCGRQQPPNSITSSGNSLFVRFQSGSSSQSRGFRAQFRQEC 1620

  Fly  1652 GGRLST-GEGYLQSRL-------DEECSWLV-TSPEGSKLSLIINQLECPKCNAVSQNCS-EGLQ 1706
            |..:.| ....:.|.|       ::.|:|:: ..|..:.::|.........    |.:|: :.::
Mouse  1621 GAHIITDSSDSISSPLYPANYPNNQNCTWIIEAQPPFNHIALSFTHFHLQS----STDCTRDFVE 1681

  Fly  1707 LLN--DDDQVLLYQMC---RDHPANLIVPANNVRILTHGI----RLQAQFSTFENSCGGNITSAS 1762
            :|:  |.|..:..:.|   ..||......|..||.::..:    ...|.:|...::|||...:..
Mouse  1682 ILDGRDSDAPVQGRYCGTSLPHPIISFGNALTVRFVSDSVYGFDGFHAIYSASTSACGGTFYTGD 1746

  Fly  1763 GSLSSPNYPDSYPANIECVWSIRTRPGNALEITFEAMDIVRSEHCNDDFLEIR-SSVQGPLLALY 1826
            |..:||.||:.|.:|.||||:|.:.|||.|:::|.:..:..|.:||.||:||| .:..|.|:..|
Mouse  1747 GIFNSPGYPEDYHSNTECVWNIASSPGNHLQLSFLSFQLENSLNCNKDFVEIREGNATGHLMGRY 1811

  Fly  1827 CDKNLPETPLVVHS-ELWIKFRSRPGNTAGGFRFRWTYVHNNEINSGINGTIEPP--PPLFVSNE 1888
            |..:||.....:.. .||::|.|....|..||:.|:..:..|:...|.:|.|..|  |..:..|.
Mouse  1812 CGNSLPGNYSSIEGHNLWVRFVSDGSGTGMGFQARFKNIFGNDNIVGTHGKIATPFWPGNYPLNS 1876

  Fly  1889 DQPFTWRLFTDFKKVF---VLQFEE------YISGLILFDGYDDNALAVNIPVSPWR--FTSSSN 1942
            :  :.|.:..|...:.   :|:.:.      :...|.::||:|.::..:.......|  |:||.|
Mouse  1877 N--YRWTVNVDSSHIIHGRILEMDIELTTNCFYDSLKIYDGFDIHSRLIGTYCGTQRESFSSSRN 1939

  Fly  1943 VVYLKTVNDALTH---FRLKWGVLDSNLVASNLSLTT---GGCTKELTLSHHGD--IELSSPGYP 1999
            .:..:..:|:...   |.|:|..:|    .||::|.|   |.|...:..   ||  :...|||:|
Mouse  1940 SLTFQFSSDSSKSGRGFLLEWFAVD----VSNVTLPTIAPGACGGYMVT---GDTPVFFFSPGWP 1997

  Fly  2000 HGYAPNLNCEWTIRSQFPSHHIYAHSIIVDLEDYPACSADYLSIQSSRDLIKWKNELHACKASQI 2064
            ..|....:|.|.|.:  |...:..:.:.:|:|...:||.|.|.|:.....:..:..: .|..|..
Mouse  1998 GPYGNGADCIWIIYA--PDSTVELNILSMDIEAQLSCSYDKLIIKDGDSRLSQQLAV-LCGRSVP 2059

  Fly  2065 APVHGT-PYLRLQFRSDVSINGTGFRAKLRTSCGSNM---TGIVGTIPQ------ENLFDECAWH 2119
            .|:..| .|:.::|.||.|:.|.||.|..:.|||..:   .||: |.|:      .||  .|:||
Mouse  2060 GPIRSTGEYMYIRFTSDGSVTGAGFNASFQKSCGGYLHADRGII-TSPKYPDNYLPNL--NCSWH 2121

  Fly  2120 IDVRPGRKIDIAINYNNMPPIAV------CEA--YGLIYDGVDEHASLLEHTRFGNQMGIRR--- 2173
            :.|:.|  :.||:::..  |..:      |..  |.::.:|.|.|:..|     |...|..|
Mouse  2122 VLVQSG--LTIAVHFEQ--PFQIQNRDSSCSQGDYLVLRNGPDNHSPPL-----GPSGGNGRFCG 2177

  Fly  2174 -----TQFRTSGSHAYIKYHIGRSRINGLCLWNLTYREFN-ECNGEIQLNQQAPNYTIMSPGYPY 2232
                 |.| ||.:..:|::....|  ||...:.:.|...: .|.|.|.::....:..:.||.||.
Mouse  2178 IYTPSTLF-TSDNEMFIQFISDNS--NGGQGFKIRYEAKSLACGGTIYIHDANSDGYVTSPNYPA 2239

  Fly  2233 LPHPHAECTWLVMAPPGETIAVDFDEQFEL-SARHCDKENVEFFDGATKLARLLLRTC--RKPQN 2294
            ....||||.|::.||.|.:|.:.|::||.: ...:|....:|..|||...|.:|.:.|  ..|:|
Mouse  2240 NYPQHAECIWILEAPSGRSIQLQFEDQFNIEETPNCSASYLELRDGANSNAPVLSKLCGHTLPRN 2304

  Fly  2295 TVRTTGNLLLVHYQSQLNEPTGGFRLNLSLSTCGGQFSASAGFISSENYP-HLGGYPKPSVCEYS 2358
            .|.:.| |:.:.:.::......||:...|:.:|||..|..:|.|.|..|| .|  |.....|::.
Mouse  2305 WVSSRG-LMYLKFHTEGGSGYMGFKAKYSIVSCGGTVSGDSGVIESVGYPTRL--YANNVFCQWH 2366

  Fly  2359 ILLPKNAFIRLNITDLHLPYDANGTSSDRLEIVDYEDRTQKLMVLDGR-TKTSILFTLNT--NAA 2420
            |......::.:...|.:| ..:.|.:.|.:||  :|:.|..:::  || ...||..:::|  |.|
Mouse  2367 IQGLPGHYLTIRFEDFNL-QSSPGCAKDFVEI--WENHTSGILL--GRYCGNSIPSSVDTSSNVA 2426

  Fly  2421 TIRFVAVQNVNNYRGFKIRYERYVGTCSRDINGASGDIVIP----PMPQSVWLRFCRLRISVPKG 2481
            :||||...:|.: .||:::::.....|..|::|.:|....|    |.|..   |.|...|:|.:|
Mouse  2427 SIRFVTDGSVTD-SGFRLQFKSSREVCGGDLHGPTGTFTSPNYPNPNPHP---RICEWTINVHEG 2487

  Fly  2482 QRVRLNLLNLSNIRVVKRNDTNRSFMQIGRLESMAHFS-FYNDANSLSKIAEFRIDGGYNGSGII 2545
            :::   :|..:|:|:..:...|        .|.:..|: ..|::..|.|:.. |:    |.:...
Mouse  2488 RQI---ILTFTNLRLSTQQSCN--------TEHLIVFNGIRNNSPRLQKLCS-RV----NVTNEF 2536

  Fly  2546 ESTDNYMLVVVMTNQLDLSATP---LRARYSSSEPTVCPPNIGDQATGSISIQSLLQVPGYH--- 2604
            :|:.|.|.|:..|:    .:.|   ..|.|:|||..||...:...:.|:.|      .|||:
Mouse  2537 KSSGNTMKVIFFTD----GSRPYGGFTASYTSSEDAVCGGTLPSVSGGNFS------SPGYNGIR 2591

  Fly  2605 -------C--------------TIKFVGTDSAT---LTFKVEEYLFQTAGGPAVVFRDDIT--NI 2643
                   |              :|.|:|....:   .||.|.|:....|.||.:.....::  .:
Mouse  2592 DYARNLDCEWTLSNPNRENSSISIHFLGLSLESHQDCTFDVLEFRVGNADGPLIEKFCSLSAPRV 2656

  Fly  2644 PVKAMYANVTNSFVSVVTSAGSVTLLNSKNVKLRRFRATYRRHNCGGRLQAAEGVTIESPDLLTT 2708
            |:...|..|...|||            ::.|:...|...|...|||| :|..|...|.||:
Mouse  2657 PLVIPYPQVWIHFVS------------NERVEYTGFYVEYSFTNCGG-IQTGENGVISSPN---- 2704

  Fly  2709 LNDAYGE-VECLWTLSNSNGYVLEGNVTLTD-------RCDREYIVIFSGQSE----VGRICRGM 2761
            ..:.|.. .:|.|.|....|:.:  .:|.:|       .|..:.:.:.:|.|.    :||.| |.
Mouse  2705 YPNLYSRWTQCSWLLEAPEGHTI--TLTFSDFSVENHPTCTSDSVTVRNGDSPGSPIIGRYC-GQ 2766

  Fly  2762 AM------NSTLLERPFSTILYHSESRLAQQSKFILQAW--KSVSSGNAIRIDHRPSPPVTISS- 2817
            ::      .|..|...|:|   :::.    ||:.....|  .::..|..:..|:.     ||.|
Mouse  2767 SVPGPIQSGSNQLVVTFNT---NNQG----QSRGFYATWNTNTLGCGGTLHSDNG-----TIKSP 2819

  Fly  2818 ---KNYLESKQRIWEFVTNDGLSLRLHFLERIFIVSSPN-CSTDRLTVERYDQTTEEYIEVTSLC 2878
               :.:.|:.:..|..||::.....:.|.....|.||.: |....:.|......|.:.:..|| |
Mouse  2820 HWPQTFPENSRCSWTAVTHESKHWEISFDSNFRIPSSDSQCRNSFVKVWEGMLETNDALLATS-C 2883

  Fly  2879 GRQAANDILVPSARMRVIFQTNSNITGDGFSFQVIPSCDSVLLAGAEIQTLASPSWAAFRGRQFN 2943
            |..|.:.|:........:|| :..:...|||...|..|....  .:....:.||::........|
Mouse  2884 GNVAPSPIVTLGNIFTAVFQ-SEEMPAQGFSASFISRCGRTF--NSSTGDIVSPNFPKHYDNNMN 2945

  Fly  2944 CSYTFYAHDNHQVV---VSVRTRGRPWASYACSRSYFEAYRRGDGNGVGEESIGRLCPEFEVKG- 3004
            |:|.........|:   ||.....|...|..|.   ::......|:.:....:..:|....::.
Mouse  2946 CNYYIDVAPQSLVILTFVSFHLEDRSAVSGTCD---YDGLHIIKGHNLSSTPLVTICGSETLRPL 3007

  Fly  3005 --NGRVRLRYVSP---LSRWFEMQYQLIQCGGNYSTSFTLRPPQNEDSSVYAHNTLCEWRITAPP 3064
              :|.|.|.:.|.   ....|::.|::..|||.||.::.:....:...:.|.:|..|.:.:....
Mouse  3008 TIDGPVMLNFYSDAYITDFGFKISYRVANCGGIYSGTYGVLNSPSFSYTNYPNNVYCVYSLQVRN 3072

  Fly  3065 QHAVVIEFKYFDMESSRNCGFDSLTIYRGHVVSEEQRTGLLCGNVTNPETIIVNSNEALIVLTTD 3129
            ...:::.|..|::..|..|..|.|.::.|..:. .:..|..||: |.|:.|...:|...::..||
Mouse  3073 DRLILLRFNDFEIVPSNLCSHDYLEVFDGPSIG-NRSIGKFCGS-TLPQVIKSTNNSLTLLFKTD 3135

  Fly  3130 SSNSYRGFLASVRFT----PNCNEHVALDLEVPRMSVMRQYVVNISES-------LLCIFQASAP 3183
            ||.:.||:..|.|.|    ..|..::..|        .:.:|....:|       |.||:...||
Mouse  3136 SSQTARGWKVSFRETIGPQQGCGGYLTED--------SKSFVSPDHDSDGLYDKGLNCIWYIIAP 3192

  Fly  3184 PDYRISLEVRKLQLADDVVCRTCS--YLEIHDSKDVEGQNLGRYYGGTNGNEPSNRTKVFSS--- 3243
            .:..:.|......|.:......|:  |::|.|...:.....||:.|       |:|...|.|
Mouse  3193 ENKLVKLTFNAFTLEEPSSPGKCTFDYVQIADGASINSYLGGRFCG-------SSRPAPFISSGN 3250

  Fly  3244 ------FSDMSFKLIATTGQAQKNISFELILQMVRTVCGQGEYDLRLNETITLGMQYDNSTRFYE 3302
                  .||:|.::          ..|......|...|| |.|:.......|...|..|..|.:.
Mouse  3251 FLTVQFVSDISIQM----------RGFNATYTFVDMPCG-GTYNATSMPQNTSSPQLSNIRRPFS 3304

  Fly  3303 GSIQCLWIIKNKGDVELEFRKLRLKEISQGTGKCTDYLKLSKPYFSR---SYCGQHDKSFKIVEE 3364
               .|.|:|:.....:::....:|:..||...:.:..|:.|:.....   .:||.:..:..:...
Mouse  3305 ---TCTWVIEAPPHQQVQITVWKLQLPSQDCSRSSLELQDSEQTNGNQVTQFCGANYTTLPVFYS 3366

  Fly  3365 VNESNLQLAFHSDGLEESQ----GFEVIIRRKSTCNRNYTELSQVIDT-------SNLTNCTDYI 3418
             :.|...:.|.||.|..:.    .:|:     :.|||.|.:....:.:       :|..:|:..:
Mouse  3367 -SGSTAVVVFKSDFLNRNSRVHFTYEI-----ADCNREYNQAFGNLKSPGWPQGYANNLDCSIIL 3425

  Fly  3419 RVPRGYSITLYVMTV-LFDSFD--NNYFRVIDVQSNKT--------------IFTNSDIQWETKA 3466
            |.|:.:.|:|:.... |.||..  |::..|.:..|:.:              ||:.|
Mouse  3426 RAPQNHRISLFFYWFQLEDSRQCMNDFLEVRNGSSSSSPLLGKYCSNLLPNPIFSQS-------- 3482

  Fly  3467 MITSTNELRL-----ESRQVSSLKFFYFSTSNQFPGGCGGDLAVGGSVGSYLENPSYEGR--NSS 3524
                 |||.|     :|......:..:.|:    |.||||.|.  |:.| .|.||.:...  |::
Mouse  3483 -----NELYLHFHSDDSDTHHGYEIIWASS----PTGCGGTLL--GNEG-ILANPGFPDSYPNNT 3535

  Fly  3525 LCTWKISVPAGGSLRFSFAEFNMGSESNCDLDNVRFYDSVVDDQRLVKAICG-SRIPDMFTIAKN 3588
            .|.|.|..|:|..|...|...::.|...||.:.:..::....:.......|| ..:...|..:.|
Mouse  3536 HCEWTIVAPSGRPLSVGFPFLSIDSPGGCDQNYLILFNGPDANSPPFGPFCGIDTVVAPFHASSN 3600

  Fly  3589 NVII 3592
            .|.|
Mouse  3601 RVFI 3604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42255	NP_729748.3	EGF_CA	156..190	CDD:238011	16/33 (48%)
		EGF_CA	192..233	CDD:238011	19/40 (48%)
		EGF_CA	290..328	CDD:214542	20/39 (51%)
		EGF_CA	330..374	CDD:214542	26/43 (60%)
		EGF	427..455	CDD:278437	10/27 (37%)
		EGF_CA	462..496	CDD:238011	14/35 (40%)
		CUB	503..619	CDD:238001	39/116 (34%)
		CUB	624..738	CDD:238001	38/117 (32%)
		CUB	745..854	CDD:238001	36/114 (32%)
		CUB	857..963	CDD:238001	25/117 (21%)
		CUB	1066..1179	CDD:238001	45/112 (40%)
		CUB	1185..1293	CDD:238001	36/115 (31%)
		CUB	1303..1406	CDD:238001	32/106 (30%)
		CUB	1411..1523	CDD:238001	34/132 (26%)
		CUB	1530..1648	CDD:238001	30/119 (25%)
		CUB	1754..1862	CDD:238001	42/109 (39%)
		CUB	1979..2091	CDD:238001	31/114 (27%)
		CUB	2096..2193	CDD:294042	30/121 (25%)
		CUB	2210..2321	CDD:238001	34/113 (30%)
		CUB	2327..2441	CDD:238001	35/117 (30%)
		CUB	2688..2782	CDD:294042	26/111 (23%)
		CUB	2810..2911	CDD:238001	25/105 (24%)
		CUB	3029..3143	CDD:238001	29/113 (26%)
		CUB	3169..3249	CDD:294042	21/97 (22%)
		CUB	3499..3607	CDD:238001	26/97 (27%)
Cubn	NP_001074553.1	Interaction with AMN. /evidence=ECO:0000250\|UniProtKB:O60494	39..46		1/6 (17%)
		EGF_CA	133..164	CDD:238011	16/30 (53%)
		EGF_CA	167..207	CDD:238011	19/40 (48%)
		EGF_CA	260..301	CDD:214542	20/40 (50%)
		EGF_3	306..344	CDD:289699	23/38 (61%)
		EGF_3	350..387	CDD:289699	16/37 (43%)
		EGF_CA	400..430	CDD:238011	10/30 (33%)
		EGF_CA	432..468	CDD:238011	14/38 (37%)
		CUB	474..585	CDD:238001	39/116 (34%)
		CUB	590..699	CDD:238001	37/115 (32%)
		CUB	708..815	CDD:238001	37/115 (32%)
		CUB	817..927	CDD:238001	25/117 (21%)
		CUB	932..1041	CDD:238001	25/117 (21%)
		CUB	1052..1158	CDD:238001	44/107 (41%)
		CUB	1165..1275	CDD:238001	35/114 (31%)
		CUB	1278..1388	CDD:238001	34/118 (29%)
		CUB	1391..1505	CDD:238001	35/134 (26%)
		CUB	1510..1599	CDD:238001	24/101 (24%)
		CUB	1620..1733	CDD:238001	21/116 (18%)
		CUB	1738..1847	CDD:238001	41/108 (38%)
		CUB	1859..1962	CDD:238001	21/104 (20%)
		CUB	1978..2089	CDD:238001	32/116 (28%)
		CUB	2092..2212	CDD:238001	34/134 (25%)
		CUB	2217..2333	CDD:238001	34/116 (29%)
		CUB	2336..2447	CDD:238001	35/118 (30%)
		CUB	2452..2564	CDD:238001	31/134 (23%)
		CUB	2570..2686	CDD:238001	26/133 (20%)
		CUB	2689..2800	CDD:238001	29/125 (23%)
		CUB	2805..2918	CDD:238001	27/119 (23%)
		CUB	2920..3034	CDD:238001	20/118 (17%)
		CUB	3037..3148	CDD:238001	29/112 (26%)
		CUB	3157..3273	CDD:238001	26/140 (19%)
		CUB	3278..3392	CDD:238001	23/118 (19%)
		CUB	3395..3506	CDD:238001	24/123 (20%)
		CUB	3511..3623	CDD:238001	26/97 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842307
Domainoid	1	1.000	101	1.000	Domainoid score	I6942
eggNOG	1	0.900	-	-		E1_KOG4292
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46457
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006182
OrthoInspector	1	1.000	-	-		otm43532
orthoMCL	1	0.900	-	-		OOG6_106358
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4462
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.610