DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42255 and tll1

DIOPT Version :9

Sequence 1:NP_729748.3 Gene:CG42255 / 39334 FlyBaseID:FBgn0259140 Length:3613 Species:Drosophila melanogaster
Sequence 2:NP_001008039.1 Gene:tll1 / 493401 XenbaseID:XB-GENE-479941 Length:495 Species:Xenopus tropicalis


Alignment Length:492 Identity:105/492 - (21%)
Similarity:175/492 - (35%) Gaps:181/492 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   952 GGGRGMRLEYNFVP---------NQCGGFLNEPGRR----YVTAVR--------GTFCQWFIDFP 995
            ||.:.:.|...|..         |...||.:|..|.    |||.:.        |.|        
 Frog   145 GGSQAVSLLKGFCAYNGGVQHELNHALGFYHEHNRSDRDDYVTIMYQYISPENIGNF-------- 201

  Fly   996 GRKKISIHTLGPTPSISIYDNSTSPGKLVNSYSGSVGDVFDGDLLTINLHTNWPRLEI---YSI- 1056
              .|||.:.||..     ||.|:......|::|.:.|.      .||..|.| |.:.|   |.: 
 Frog   202 --DKISTNNLGVD-----YDYSSILHYAGNAFSNTSGQ------NTIVPHPN-PNVPIGQSYGLS 252

  Fly  1057 QFDIVQ------QDSCGGTFTARFGYIKSPNWPKNYGESQMCEWILRAPFGHRIELVVHNFTLEE 1115
            ..|:::      .|.|....:|..|.:.|.|:|.||..:..|.|::|.| ..::.|..:.|.:::
 Frog   253 NLDVLKINRLYGCDECSTLLSAPNGTLTSTNYPSNYQNNANCVWLIRTP-SDQVTLSFNAFNVQK 316

  Fly  1116 EYSSTGCWTDWLEIRNGDSESSPLI-GRYCG-NEIPSRIPSFGNVLHLKFKSDDSMEEKGFLLSW 1178
               |..|.:|::.:.:|.:.|:|:| .:.|| ..:|..|.|...:| ::|.:|.::...||..|:
 Frog   317 ---SQSCTSDYIRVYDGATTSAPMILDKTCGTGPLPVMIASTNRML-VEFVTDSAITAPGFKASY 377

  Fly  1179 QQMGAGCGGKLSSSMGTIHSPHLLAGNRGILACDWQIIVAEGSRVSLQLRSNDNRICSGQLTLYD 1243
            .                                                                
 Frog   378 S---------------------------------------------------------------- 378

  Fly  1244 GPTTASNPIVIRCNGTIAKPLQSTGNRVLVRYDVGHDAPDGTDFMLNYQTNCRVRLEGLQGAIET 1308
                     .::|.||...|.::                                       :.|
 Frog   379 ---------TVQCGGTFYTPSRN---------------------------------------VTT 395

  Fly  1309 PNFPENYPPGQDCEWDIRAGGRKNHLQLIFSHLSVEKFSSICLNDYVSLVDMLDDQTLSEQHL-- 1371
            ||:|::|||..||::.|.| .....:.|..::..||| |:.|..||   :::.|..::|...:  
 Frog   396 PNYPKSYPPNLDCQFIITA-PTSYKVALNINNFFVEK-SANCQYDY---LEIYDGNSMSAPKIGS 455

  Fly  1372 --CTNDGLEPITTVGNRLLLRFKSDSSVELQGFRAEY 1406
              |:......:.:.|..:||||.||:||::.||.|.|
 Frog   456 RYCSYQVFNVMVSSGRSMLLRFHSDASVQMYGFTASY 492

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42255NP_729748.3 EGF_CA 156..190 CDD:238011
EGF_CA 192..233 CDD:238011
EGF_CA 290..328 CDD:214542
EGF_CA 330..374 CDD:214542
EGF 427..455 CDD:278437
EGF_CA 462..496 CDD:238011
CUB 503..619 CDD:238001
CUB 624..738 CDD:238001
CUB 745..854 CDD:238001
CUB 857..963 CDD:238001 3/10 (30%)
CUB 1066..1179 CDD:238001 32/114 (28%)
CUB 1185..1293 CDD:238001 4/107 (4%)
CUB 1303..1406 CDD:238001 34/106 (32%)
CUB 1411..1523 CDD:238001
CUB 1530..1648 CDD:238001
CUB 1754..1862 CDD:238001
CUB 1979..2091 CDD:238001
CUB 2096..2193 CDD:294042
CUB 2210..2321 CDD:238001
CUB 2327..2441 CDD:238001
CUB 2688..2782 CDD:294042
CUB 2810..2911 CDD:238001
CUB 3029..3143 CDD:238001
CUB 3169..3249 CDD:294042
CUB 3499..3607 CDD:238001
tll1NP_001008039.1 ZnMc_hatching_enzyme 83..265 CDD:239810 33/141 (23%)
CUB 269..379 CDD:238001 31/187 (17%)
CUB 382..494 CDD:238001 39/155 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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