DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG42255 and CG6763

DIOPT Version :9

Sequence 1:NP_729748.3 Gene:CG42255 / 39334 FlyBaseID:FBgn0259140 Length:3613 Species:Drosophila melanogaster
Sequence 2:NP_001262871.1 Gene:CG6763 / 42754 FlyBaseID:FBgn0039069 Length:354 Species:Drosophila melanogaster


Alignment Length:423 Identity:86/423 - (20%)
Similarity:143/423 - (33%) Gaps:132/423 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly  1902 KVFVL--------QFEEYISGLILFDGYDDNALAVNIP------VSPWRFTSSSNVVYLKTVNDA 1952
            |||::        |...|:|    :|..||..: :.:|      :.|   |...:::.|..:..|
  Fly     4 KVFLVLALALSSCQALPYVS----YDDVDDTEV-IELPGNGIEEIPP---TLGKDIIDLTPLGTA 60

  Fly  1953 LTHFRLKWGVLDSNLVAS---NLSLTTGGCTKELTLSH-HGD-------------IELSSPGYPH 2000
            |      :|..|..|.|:   |.|........|...|: .||             :...|..:|:
  Fly    61 L------FGKPDEELTANRVGNFSADADEMNPEELGSYLEGDMLVPQTDLIMKNGLPTQSSRWPN 119

  Fly  2001 GYAPNLNCEWTIRSQFPSHHIYAHSIIVDLEDYPACSADYLSIQSSRDLIKWKNELHACKASQIA 2065
            |..|     :.||..|.:..:......:. |.:......::...|.||.|..:.:...|.:| :.
  Fly   120 GVVP-----YEIRGNFNARDMATIENAIG-EYHRRTCIRFVKRSSERDYISIRGDNSGCWSS-VG 177

  Fly  2066 PVHGTPYLRLQFRSDVSINGTGFRAKLRTSCGSNMTGIVGTIPQENLFDECAWHIDVRPGRKIDI 2130
            .|.|...:.||....:|..||.....:..         :|.:.::|..:...:           :
  Fly   178 RVGGKQEVNLQSPGCLSRPGTAMHELMHA---------LGFLHEQNRMERDGY-----------V 222

  Fly  2131 AINYNNMPPIAV--------CEAYGLIYDGVDEHASLLEHTRFGNQMGIRRTQFRTSGSHAYIKY 2187
            ||.|||:...|:        .||:|:.||             :|:.|...:..|..:|....:  
  Fly   223 AIQYNNVQSSAMNNFEKAARTEAFGVPYD-------------YGSVMHYSKNAFSINGQPTIL-- 272

  Fly  2188 HIGRSRINGLCLWNLTYREFNECNG----EIQ-LNQQ----APNYTIMSPGYPY-LPHPHAECTW 2242
               ..:.||.       .:..:.||    :|| ||:.    ..|...::||.|. .|.|.|.   
  Fly   273 ---AMQANGA-------DKMGQRNGFSDYDIQKLNRMYDCGTVNAVPVAPGLPAPAPAPGAP--- 324

  Fly  2243 LVMAPPGETIAVDF-----------DEQFELSA 2264
               |..|..|...|           ||:.|.|:
  Fly   325 ---AGSGNPIVDSFIGGLISGLGLGDEKKETSS 354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42255NP_729748.3 EGF_CA 156..190 CDD:238011
EGF_CA 192..233 CDD:238011
EGF_CA 290..328 CDD:214542
EGF_CA 330..374 CDD:214542
EGF 427..455 CDD:278437
EGF_CA 462..496 CDD:238011
CUB 503..619 CDD:238001
CUB 624..738 CDD:238001
CUB 745..854 CDD:238001
CUB 857..963 CDD:238001
CUB 1066..1179 CDD:238001
CUB 1185..1293 CDD:238001
CUB 1303..1406 CDD:238001
CUB 1411..1523 CDD:238001
CUB 1530..1648 CDD:238001
CUB 1754..1862 CDD:238001
CUB 1979..2091 CDD:238001 25/125 (20%)
CUB 2096..2193 CDD:294042 17/104 (16%)
CUB 2210..2321 CDD:238001 21/76 (28%)
CUB 2327..2441 CDD:238001
CUB 2688..2782 CDD:294042
CUB 2810..2911 CDD:238001
CUB 3029..3143 CDD:238001
CUB 3169..3249 CDD:294042
CUB 3499..3607 CDD:238001
CG6763NP_001262871.1 Astacin 116..304 CDD:279708 45/239 (19%)
ZnMc_astacin_like 119..300 CDD:239807 44/232 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45444860
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.830

Return to query results.
Submit another query.