Protein Alignment CG42255 and nas-39

DIOPT Version :9

• Sequence 1: NP_729748.3
• Gene: CG42255 / 39334
• FlyBaseID: FBgn0259140
• Length: 3613
• Species: Drosophila melanogaster
• Sequence 2: NP_001360030.1
• Gene: nas-39 / 3565986
• WormBaseID: WBGene00003555
• Length: 928
• Species: Caenorhabditis elegans
• Alignment Length: 954
• Identity: 200/954 - (20%)
• Similarity: 322/954 - (33%)
• Gaps: 329/954 - (34%)

  Fly  1183 AGCGGKLSSSMGTIHSPHLLAGNRGILACDWQIIVAEGSRVSLQLR----SNDNRICSGQ----L 1239
            |.|||.|....|.:...|  ||     .|.|.||..:|..:.|.:.    |..:.:|..:    :
 Worm   247 AECGGTLMQESGNLAIQH--AG-----VCTWHIISPQGHTIFLNITGSTLSPPSSLCGKEEDNVI 304

  Fly  1240 TLYDGPTTASNPIVIR-CNG-TIAKPLQSTGNRVLVRYDVGHDAPDGTDFMLNYQTNCRVRLEGL 1302
            |:.|| .:.|:|::.| |.| ::.:.:.|:|||:|::  |....|..:.....|...|...:...
 Worm   305 TVRDG-VSISSPVLDRICGGDSLFRTIASSGNRMLIQ--VRSSTPAASLPFATYYAICGGPIYAN 366

  Fly  1303 QGAIETPNFPENYPPGQDCEWDIRAGGRKN-HLQLIFSHLSVEK---FSSICLNDYVSLVDMLDD 1363
            :|.|.:|.:||:|||..||:|.|....... .::.::.||...|   :..:.|.:.:|.....|.
 Worm   367 EGVIHSPKYPESYPPNSDCQWTIHVDENSQVAIEFVYFHLEQHKECIYDRLILTEGISKNSKKDG 431

  Fly  1364 QTLSEQHLCTNDGL---EPITTVGNRLLLRFKSDSSVELQGFRAEYKRIGCGEHLRESGGRFESP 1425
            :.:||    |..||   :.|.:..|::.|||.||:||:..||...:.:     .|.|
 Worm   432 KEMSE----TFCGLIEKKTIVSKTNQISLRFFSDNSVQKTGFELRFTK-----ELNE-------- 479

  Fly  1426 NAPFSVDMDCVWIITASEGNQIRLLLHEVYFEAPQIECRDAESSLSVSAPSGYNSSVVLFRSCHE 1490
                     |     |::.|    :.|..        |.:.......:...||:.|...| ||
 Worm   480 ---------C-----ATDKN----ICHHY--------CVNTVGGFKCACRVGYSLSSNGF-SC-- 515

  Fly  1491 ETQTQTFTSPGNELVIRFVSSSAPSRKYFKASFVQVPASCGGYISASSGVLTTPGFHNHQDSKNV 1555
                                                .::||||:.||:|.:::|.|..
 Worm   516 ------------------------------------DSTCGGYLKASNGSISSPNFPE------- 537

  Fly  1556 ANYTSNIECVWTVEVTNGYGIRPHFEQFNLTD-SGNCSVSFVELTKLEPDNKEIFLEKTCGEDSP 1619
             .|.::..|:|.:|..:||.|..:|.:||:.. ...|:..:|::    .|:     ||.|||...
 Worm   538 -MYPNSKTCIWEIEAPDGYHIFLNFTKFNVEGMKTECAYDYVKI----GDS-----EKLCGEYHE 592

  Fly  1620 MIRIVHGR-KLRVRFKSQA-----GTWGRFIMYFERQCGGRLSTGEGYLQSRLDEECSWLVTSPE 1678
            .:.....| ::|:.|.|.:     |.:..||..|: :|....:..|...|:||.   |::.|
 Worm   593 ALLFTTPRNRVRIEFSSDSSVERDGFFANFIADFD-ECQNDNAGCEHTCQNRLG---SYVCT--- 650

  Fly  1679 GSKLSLIINQLECPKCNAVSQNCSEGLQLLNDDDQVLLYQMCRDHPANLIVPANNVRILTHGIRL 1743
                                  |:.|..|..|...      |:
 Worm   651 ----------------------CNPGYILAEDKHN------CK---------------------- 665

  Fly  1744 QAQFSTFENSCGGNITSASGSLSSPNYPDSYPANIECVWSIRTRPGNALEITFEAMDIVRSEHCN 1808
                   |.||...:.:.:|.::|||||:.||....|.|...|.||:.|.:||.:..:.....|.
 Worm   666 -------EGSCFFEVNAPAGDINSPNYPNDYPKGQNCSWHFVTTPGHRLMLTFSSFQVEEHAQCK 723

  Fly  1809 DDFLEIRSSVQG--PLLALYCDKNLPETPLVVHSELWIKFRSRPGNTAGGFRFRWTYVHNNEINS 1871
            .|.:.:.....|  .|..::|
 Worm   724 YDAVSVYDGGDGSAQLAGVFC-------------------------------------------- 744

  Fly  1872 GINGTIEPPPPLFVSNEDQPFTWRLFTDFKKVFVLQFEEYISGLILFDGYDDNALAVNIPVSPWR 1936
            |:     .||||.:
 Worm   745 GL-----APPPLLL--------------------------------------------------- 753

  Fly  1937 FTSSSNVVYLKTVNDALTHFRLKWGVLDSNLVASNLSLTTGGCTKELTLSHHGDIELSSPG--YP 1999
              ||||.:||...:||        .|......|...||..|..|.|           |:||  |.
 Worm   754 --SSSNELYLTFSSDA--------SVSRRGFQAHYTSLCGGRLTAE-----------STPGHIYS 797

  Fly  2000 HG------YAPNLNCEWTIRSQFPSHHIYAHSIIVDLEDYPACSADYLSIQSSRDLIKWKNELHA 2058
            |.      |..|.:|.|.:|::.|...:.......::|....|..||:.|....:....:.....
 Worm   798 HATFSDSKYGKNQDCSWIVRAKSPGRGVRIQFSTFNIESEEGCQYDYIEIYDGPEATLERLVGRF 862

  Fly  2059 CKASQIAPVHGT-PYLRLQFRSDVSINGTGFRAKLRTSCGSNMT 2101
            |..:....:..| |.|.|...:|.:....||.|:.|.:..|:.|
 Worm   863 CGDTSPEVITSTGPELLLIMHTDNAEEEKGFVAEYREAPRSSST 906

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42255	NP_729748.3	EGF_CA	156..190	CDD:238011
		EGF_CA	192..233	CDD:238011
		EGF_CA	290..328	CDD:214542
		EGF_CA	330..374	CDD:214542
		EGF	427..455	CDD:278437
		EGF_CA	462..496	CDD:238011
		CUB	503..619	CDD:238001
		CUB	624..738	CDD:238001
		CUB	745..854	CDD:238001
		CUB	857..963	CDD:238001
		CUB	1066..1179	CDD:238001
		CUB	1185..1293	CDD:238001	32/117 (27%)
		CUB	1303..1406	CDD:238001	34/109 (31%)
		CUB	1411..1523	CDD:238001	13/111 (12%)
		CUB	1530..1648	CDD:238001	34/124 (27%)
		CUB	1754..1862	CDD:238001	22/109 (20%)
		CUB	1979..2091	CDD:238001	26/120 (22%)
		CUB	2096..2193	CDD:294042	2/6 (33%)
		CUB	2210..2321	CDD:238001
		CUB	2327..2441	CDD:238001
		CUB	2688..2782	CDD:294042
		CUB	2810..2911	CDD:238001
		CUB	3029..3143	CDD:238001
		CUB	3169..3249	CDD:294042
		CUB	3499..3607	CDD:238001
nas-39	NP_001360030.1	ZnMc_BMP1_TLD	48..247	CDD:239808	200/954 (21%)
		CUB	268..343	CDD:214483	22/77 (29%)
		CUB	359..474	CDD:238001	35/118 (30%)
		FXa_inhibition	480..515	CDD:373209	9/52 (17%)
		CUB	519..622	CDD:366096	32/119 (27%)
		FXa_inhibition	629..664	CDD:373209	11/68 (16%)
		CUB	669..780	CDD:238001	37/220 (17%)
		CUB	782..898	CDD:238001	28/126 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810