DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42255 and Astl

DIOPT Version :9

Sequence 1:NP_729748.3 Gene:CG42255 / 39334 FlyBaseID:FBgn0259140 Length:3613 Species:Drosophila melanogaster
Sequence 2:NP_001099974.1 Gene:Astl / 296129 RGDID:1562279 Length:436 Species:Rattus norvegicus


Alignment Length:220 Identity:43/220 - (19%)
Similarity:80/220 - (36%) Gaps:70/220 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly  1828 DKNLP---------ETP---LVVHSELWIKFRSRPGNTAGGFRFRWTYVHNNEINSGINGTIEPP 1880
            ||::|         |||   .:|..::   .|..|        ||...|.||:...|::|.:| .
  Rat    52 DKDIPAINQGLISEETPESSFLVEGDI---IRPSP--------FRLLSVTNNKWPKGVDGIVE-I 104

  Fly  1881 PPLFVSNEDQP---FTWRLFTDFKKVFVLQF------EEYISGLIL---FDGYDDNALAVNIPVS 1933
            |.|..|..|:|   .....|.:|::...::|      .:::|.|.:   |.|...:.....:.::
  Rat   105 PFLLSSKYDEPSRQVIMEAFAEFERFTCIRFVAYRGQRDFVSILPMAGCFSGVGRSGGMQVVSLA 169

  Fly  1934 PWRFTSSSNVVYLKTVN-----------DALTHFRLKWGVL------------DSNLVAS-NLSL 1974
            |........:|..:.::           |...:.|:.|..:            :||::|. :.| 
  Rat   170 PTCLQKGRGIVLHELMHVLGFWHEHSRADRDRYIRVNWNEILPGFEINFIKSRNSNMLAPYDYS- 233

  Fly  1975 TTGGCTKELTLSHHGDIELSSPGYP 1999
                     ::.|:|....|..|.|
  Rat   234 ---------SVMHYGRFAFSWRGQP 249

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42255NP_729748.3 EGF_CA 156..190 CDD:238011
EGF_CA 192..233 CDD:238011
EGF_CA 290..328 CDD:214542
EGF_CA 330..374 CDD:214542
EGF 427..455 CDD:278437
EGF_CA 462..496 CDD:238011
CUB 503..619 CDD:238001
CUB 624..738 CDD:238001
CUB 745..854 CDD:238001
CUB 857..963 CDD:238001
CUB 1066..1179 CDD:238001
CUB 1185..1293 CDD:238001
CUB 1303..1406 CDD:238001
CUB 1411..1523 CDD:238001
CUB 1530..1648 CDD:238001
CUB 1754..1862 CDD:238001 11/45 (24%)
CUB 1979..2091 CDD:238001 5/21 (24%)
CUB 2096..2193 CDD:294042
CUB 2210..2321 CDD:238001
CUB 2327..2441 CDD:238001
CUB 2688..2782 CDD:294042
CUB 2810..2911 CDD:238001
CUB 3029..3143 CDD:238001
CUB 3169..3249 CDD:294042
CUB 3499..3607 CDD:238001
AstlNP_001099974.1 Astacin 92..283 CDD:279708 30/169 (18%)
ZnMc 99..281 CDD:294052 28/162 (17%)
ImpA_N <305..420 CDD:303075
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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