DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42255 and Astl

DIOPT Version :9

Sequence 1:NP_729748.3 Gene:CG42255 / 39334 FlyBaseID:FBgn0259140 Length:3613 Species:Drosophila melanogaster
Sequence 2:NP_001277932.1 Gene:Astl / 215095 MGIID:3046414 Length:435 Species:Mus musculus


Alignment Length:406 Identity:79/406 - (19%)
Similarity:124/406 - (30%) Gaps:172/406 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly  2626 FQTAGGPAVVFRDDITNIPVKAMYANVTNSFVSVVTSAGSVTLLNSKNVKLRRFRATYRRHNCGG 2690
            |...|.|  ||:|  .:||.      :....:|..|...|. |:....::...||.....:|   
Mouse    42 FTPEGSP--VFQD--KDIPA------INQGLISEETPESSF-LVEGDIIRPSPFRLLSVTNN--- 92

  Fly  2691 RLQAAEGVTIESPDLLT---------TLNDAYGEVE---CLWTLSNSNGYVLEGNVTLTDRCDRE 2743
            :.....|..:|.|.||:         .:.||:.|.|   |:..::...              .|:
Mouse    93 KWPKGVGGFVEIPFLLSRKYDELSRRVIMDAFAEFERFTCIRFVAYHG--------------QRD 143

  Fly  2744 YIVI------FSGQSEVGRICRGMAMNS---TLLERPFSTIL---------YHSESRLAQQSKFI 2790
            ::.|      |||   ||| ..||.:.|   |.|.:....:|         :|..|| |.:.::|
Mouse   144 FVSILPMAGCFSG---VGR-SGGMQVVSLAPTCLRKGRGIVLHELMHVLGFWHEHSR-ADRDRYI 203

  Fly  2791 LQAWKSVSSGNAIRIDHRPSPPVTISSKNYLESKQRIWEFVTNDGLSLRLHFLERIFIVSSPNCS 2855
            ...|..:..|..|               |:::|:                              |
Mouse   204 QVNWNEILPGFEI---------------NFIKSR------------------------------S 223

  Fly  2856 TDRLTVERYDQTTEEYIEVTSLCGRQAANDILVPSARMRVIFQTNSNITGDGFSFQVIPSCDSVL 2920
            |:.|.  .||.::..:.      ||.|                         ||::..|:     
Mouse   224 TNMLV--PYDYSSVMHY------GRFA-------------------------FSWRGQPT----- 250

  Fly  2921 LAGAEIQTLASPSWAAFRGRQFNCSYTFYAHDNHQVVVSVRTRGRPWASYACSRSYFEAYRRG-- 2983
                     ..|.|            |...|...:..:|.....|....|.||||..:::.||  
Mouse   251 ---------IIPLW------------TSSVHIGQRWNLSTSDITRVCRLYNCSRSVPDSHGRGFE 294

  Fly  2984 ---DGNGVGEESIGRL 2996
               ||:.:...||.||
Mouse   295 AQSDGSSLTPASISRL 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42255NP_729748.3 EGF_CA 156..190 CDD:238011
EGF_CA 192..233 CDD:238011
EGF_CA 290..328 CDD:214542
EGF_CA 330..374 CDD:214542
EGF 427..455 CDD:278437
EGF_CA 462..496 CDD:238011
CUB 503..619 CDD:238001
CUB 624..738 CDD:238001
CUB 745..854 CDD:238001
CUB 857..963 CDD:238001
CUB 1066..1179 CDD:238001
CUB 1185..1293 CDD:238001
CUB 1303..1406 CDD:238001
CUB 1411..1523 CDD:238001
CUB 1530..1648 CDD:238001
CUB 1754..1862 CDD:238001
CUB 1979..2091 CDD:238001
CUB 2096..2193 CDD:294042
CUB 2210..2321 CDD:238001
CUB 2327..2441 CDD:238001
CUB 2688..2782 CDD:294042 25/123 (20%)
CUB 2810..2911 CDD:238001 12/100 (12%)
CUB 3029..3143 CDD:238001
CUB 3169..3249 CDD:294042
CUB 3499..3607 CDD:238001
AstlNP_001277932.1 Astacin 92..282 CDD:279708 53/315 (17%)
ZnMc 100..281 CDD:294052 51/303 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 318..356
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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