DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42255 and nas-33

DIOPT Version :9

Sequence 1:NP_729748.3 Gene:CG42255 / 39334 FlyBaseID:FBgn0259140 Length:3613 Species:Drosophila melanogaster
Sequence 2:NP_509086.2 Gene:nas-33 / 186987 WormBaseID:WBGene00003551 Length:644 Species:Caenorhabditis elegans


Alignment Length:480 Identity:96/480 - (20%)
Similarity:162/480 - (33%) Gaps:153/480 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly  1130 RNGDSES------SPLIGRYCGN--EIPSRIPSFG---NVLHLKFKSDDSMEEKGFLLSWQQMG- 1182
            |.|:|..      |....|..|:  :|.:.|||.|   |.:....|....|.|....|:..||. 
 Worm   119 RPGESYDKVIQIMSSYFNRKSGSQYDINTVIPSSGIYNNEMAANSKIAAVMFESDMALTVSQMNK 183

  Fly  1183 -AGCGGKLSSSM---GTIHS---PHLLAGNRGILACDWQIIVAEGSRVSLQLRSNDNRIC----- 1235
             |..|.::...|   ||..|   |:......|    :||      |:::..||..:...|     
 Worm   184 VAQNGFRVKRKMNLNGTTWSRNIPYRFLDTDG----NWQ------SQITNGLRHYERNTCIRFSL 238

  Fly  1236 ----SGQLTLYDGPTTASNPIVIRCNG----TIAKPLQSTGNRVLVRYDVGH--------DAPDG 1284
                |..|....|....|:  |.|..|    :|....::.|   ::.::|||        ..|:.
 Worm   239 NGGGSDYLVFSKGEGCYSS--VGRLGGPQEISIGDGCETLG---IITHEVGHALGFWHEQARPER 298

  Fly  1285 TDFMLNYQTNCRVRLEGLQGAIETPNFPENYPPGQDCEWDIRAGGRKNHLQLIFSHLSVEKF--S 1347
            ..::   :.|.:..:.||:|                 ::|.|:....|...|.:.:.||..:  .
 Worm   299 DSYV---RINRQNAINGLEG-----------------QFDKRSWSEVNEYSLPYDYGSVMHYGPK 343

  Fly  1348 SICLNDYVSLVDMLDDQTLSEQHLCTNDGLEPITTVGNRLLLRFKSDSSVELQGFRAEY------ 1406
            |...:..::.|:.:|...              |.|:|||:     ..|.::|:.....:      
 Worm   344 SFSKSSTMNTVEPVDPAF--------------INTIGNRV-----EPSFLDLKLLNTAFCSNICT 389

  Fly  1407 KRIGCG------------------------EHLRESGGRFESP-------NAPFSVDMDCVWIIT 1440
            .||.|.                        |.|:.|....|.|       |..:|...||.|.|.
 Worm   390 NRINCQHGGYADPNNCGQCTCPTGLEGTYCERLQTSNCGVELPRADYSWRNISYSGSSDCYWRIV 454

  Fly  1441 ASEGNQIRLLLHEVYFEAPQIECRDAESSLSVSAPSGYNSSVVLFRSCHEETQTQTFTSPGNELV 1505
            ::.|..:|..|..|.:....: |.:     .|...:.|:.....:|.|.:....:.. |.||.::
 Worm   455 SANGGNVRFELTYVMYRCSPV-CEE-----FVEMKAEYSHEATGYRQCCKAVLGERI-SKGNSVL 512

  Fly  1506 I--------RFV-----SSSAPSRK 1517
            |        :||     ..:||:::
 Worm   513 IISKATQNSQFVLRYREDGTAPTQR 537

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42255NP_729748.3 EGF_CA 156..190 CDD:238011
EGF_CA 192..233 CDD:238011
EGF_CA 290..328 CDD:214542
EGF_CA 330..374 CDD:214542
EGF 427..455 CDD:278437
EGF_CA 462..496 CDD:238011
CUB 503..619 CDD:238001
CUB 624..738 CDD:238001
CUB 745..854 CDD:238001
CUB 857..963 CDD:238001
CUB 1066..1179 CDD:238001 16/59 (27%)
CUB 1185..1293 CDD:238001 26/134 (19%)
CUB 1303..1406 CDD:238001 17/104 (16%)
CUB 1411..1523 CDD:238001 29/151 (19%)
CUB 1530..1648 CDD:238001
CUB 1754..1862 CDD:238001
CUB 1979..2091 CDD:238001
CUB 2096..2193 CDD:294042
CUB 2210..2321 CDD:238001
CUB 2327..2441 CDD:238001
CUB 2688..2782 CDD:294042
CUB 2810..2911 CDD:238001
CUB 3029..3143 CDD:238001
CUB 3169..3249 CDD:294042
CUB 3499..3607 CDD:238001
nas-33NP_509086.2 Astacin 200..386 CDD:279708 43/239 (18%)
ZnMc_astacin_like 203..381 CDD:239807 42/231 (18%)
CUB 442..527 CDD:294042 20/91 (22%)
TSP1 553..595 CDD:214559
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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