DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42255 and nas-17

DIOPT Version :9

Sequence 1:NP_729748.3 Gene:CG42255 / 39334 FlyBaseID:FBgn0259140 Length:3613 Species:Drosophila melanogaster
Sequence 2:NP_505892.1 Gene:nas-17 / 186923 WormBaseID:WBGene00003536 Length:448 Species:Caenorhabditis elegans


Alignment Length:411 Identity:79/411 - (19%)
Similarity:125/411 - (30%) Gaps:172/411 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly    98 RDMFHDVELKMTRIQRRIFSARNSTKRSGLNQRILRRQLQRVER-----------------VKGI 145
            :|...|.::.:|..|.||.:  .:.|||       :||:.::.:                 :|..
 Worm    54 KDGIVDGDIMLTEAQLRILN--GTAKRS-------KRQITKIWKKWPDAKVFYYYENEFTSLKRE 109

  Fly   146 LQTLA-GNLARNECL----SNPCKN-------GGTCHDAYKGFQCECPAGWQGDSCEDDVNECFT 198
            |.:.| .:::.|.|:    ||...|       ||..  :|.|........|.||.|        .
 Worm   110 LMSYAMAHISSNTCVKFQESNSATNRIRFTNTGGCA--SYIGMNGGEQTLWFGDGC--------L 164

  Fly   199 LAGTDLDGCLNNGQCINTPG----------SYRCVCRNGF------------------TGTHCRL 235
            :.||.:...:::....:|..          ||:.|..|..                  .|:....
 Worm   165 IFGTAVHEIMHSLGLFHTHSRFDRDNFLSVSYKDVPENMVGNLEKETEQTTYNAVPFEYGSTMLY 229

  Fly   236 RHNTCLFGGSRELCGEHGTCIQAAN-------------------SAGYVCICDQGWTWADANVTS 281
            |:||  ||        .||.:....                   :..|.|.|.:..|..:...| 
 Worm   230 RYNT--FG--------EGTLVSKNEDYQKTMGLRRVSFYDLVNINVRYSCGCAKSLTCENGGYT- 283

  Fly   282 ASPSACVRDVDECEPRVNPCHDECINLPGSFRCGACPTGYTGDGRFCRDID----ECASED---- 338
             :||.|.               .|:          ||||:.  |..|.:..    :..:|.    
 Worm   284 -NPSNCA---------------TCV----------CPTGFA--GTLCNEAPSNTIKLTAESYWKG 320

  Fly   339 ---NGGCSLQPRVTCTNTEGSHRCGRCPAGWTGD-------GRTCTASDSNSCNNEG-------- 385
               |.|.|..  :..||...::.....||..|.:       |.||    |..||..|        
 Worm   321 YWVNFGYSTS--IQTTNYYLAYLWITAPADKTIEVKIMDLSGFTC----SYGCNYNGVEVKYMGD 379

  Fly   386 --ICHPLAKC----EYVSDMV 400
              |.:||..|    ||::.::
 Worm   380 PRITNPLRCCAQDTEYLNQVI 400

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42255NP_729748.3 EGF_CA 156..190 CDD:238011 12/44 (27%)
EGF_CA 192..233 CDD:238011 8/68 (12%)
EGF_CA 290..328 CDD:214542 6/37 (16%)
EGF_CA 330..374 CDD:214542 11/61 (18%)
EGF 427..455 CDD:278437
EGF_CA 462..496 CDD:238011
CUB 503..619 CDD:238001
CUB 624..738 CDD:238001
CUB 745..854 CDD:238001
CUB 857..963 CDD:238001
CUB 1066..1179 CDD:238001
CUB 1185..1293 CDD:238001
CUB 1303..1406 CDD:238001
CUB 1411..1523 CDD:238001
CUB 1530..1648 CDD:238001
CUB 1754..1862 CDD:238001
CUB 1979..2091 CDD:238001
CUB 2096..2193 CDD:294042
CUB 2210..2321 CDD:238001
CUB 2327..2441 CDD:238001
CUB 2688..2782 CDD:294042
CUB 2810..2911 CDD:238001
CUB 3029..3143 CDD:238001
CUB 3169..3249 CDD:294042
CUB 3499..3607 CDD:238001
nas-17NP_505892.1 Astacin 88..271 CDD:279708 33/202 (16%)
ZnMc_astacin_like 92..267 CDD:239807 31/194 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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