DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42255 and nas-13

DIOPT Version :9

Sequence 1:NP_729748.3 Gene:CG42255 / 39334 FlyBaseID:FBgn0259140 Length:3613 Species:Drosophila melanogaster
Sequence 2:NP_510549.3 Gene:nas-13 / 185492 WormBaseID:WBGene00003532 Length:450 Species:Caenorhabditis elegans


Alignment Length:414 Identity:82/414 - (19%)
Similarity:137/414 - (33%) Gaps:128/414 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   989 QWFIDFPGRKKISIHTLGPTPSISIYDNSTSPGKLVNS--YSGSVGDVFDGDLLTINLHTNWPRL 1051
            |||::                ..::|:.....|.:.||  .|.|: :.|.||.         |..
 Worm    64 QWFVN----------------DSAMYNPLRFEGDIANSGLNSRSI-NTFFGDS---------PLF 102

  Fly  1052 EIYSIQFDIVQQDSCGGTF----TARFGYIKSPNWPKNYGESQMCEWILRAPFGHRIELVVHNFT 1112
            .|:.:|.:.|:|     |:    .||..|..|..: .:|..|::.|.|                 
 Worm   103 GIFGVQRNAVRQ-----TYLKWEQARIPYTISSQY-SSYSRSKIAEAI----------------- 144

  Fly  1113 LEEEYSSTGCW---------TDWLEIRNGDSESSPLIGRYCGNE---IPSRIPSFGNVLHLKFKS 1165
              |||....|.         .|::.|...|...| |:||..|.:   :.......|.::|     
 Worm   145 --EEYRKKTCIDFSPKSAGDLDYIHIVPDDGCYS-LVGRIGGKQPVSLGDGCIQKGIIIH----- 201

  Fly  1166 DDSMEEKGFL-------------LSWQQMGAGCG---GKLSSSM----------GTI--HSPHLL 1202
             :.|...||.             ::|..:.||..   .|.|.:|          |::  ::|...
 Worm   202 -ELMHAVGFFHEQSRADRDEYVKINWSNVEAGLQDQFDKYSLNMIDHLGTKYDYGSVMHYAPTAF 265

  Fly  1203 AGNRGILACDWQIIVAEGSRVSLQLRSNDNRICSGQLTLYDGPTTASNPI----VIRCNGTIAKP 1263
            :.|........:..|..|.|...    ::|.|....: ||:.||..:..:    ..|......|.
 Worm   266 SKNGKPTIEPIEKNVEIGQRAGF----SENDIYKINM-LYNCPTFTATTLAPENTKRVKSITKKV 325

  Fly  1264 LQSTGNRVLVRYDVGHDAPDGTDFMLNYQTNCRVRLEGLQGAIETPNFPENYPPGQDCEWDIRAG 1328
            ..:||:.:..:.::|....|..|...|...:..:.:....|..|...        :|||:..|||
 Worm   326 TSATGSPLSKKGEIGSSIGDKGDRGDNSVLSSLISIHSGLGKCEDRR--------KDCEFLARAG 382

  Fly  1329 GRKNHLQLIFSHLSVEKFSSICLN 1352
                |.:   |..|:...:..|.|
 Worm   383 ----HCE---SRFSIRFMTENCAN 399

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42255NP_729748.3 EGF_CA 156..190 CDD:238011
EGF_CA 192..233 CDD:238011
EGF_CA 290..328 CDD:214542
EGF_CA 330..374 CDD:214542
EGF 427..455 CDD:278437
EGF_CA 462..496 CDD:238011
CUB 503..619 CDD:238001
CUB 624..738 CDD:238001
CUB 745..854 CDD:238001
CUB 857..963 CDD:238001
CUB 1066..1179 CDD:238001 26/141 (18%)
CUB 1185..1293 CDD:238001 23/126 (18%)
CUB 1303..1406 CDD:238001 13/50 (26%)
CUB 1411..1523 CDD:238001
CUB 1530..1648 CDD:238001
CUB 1754..1862 CDD:238001
CUB 1979..2091 CDD:238001
CUB 2096..2193 CDD:294042
CUB 2210..2321 CDD:238001
CUB 2327..2441 CDD:238001
CUB 2688..2782 CDD:294042
CUB 2810..2911 CDD:238001
CUB 3029..3143 CDD:238001
CUB 3169..3249 CDD:294042
CUB 3499..3607 CDD:238001
nas-13NP_510549.3 Astacin 118..304 CDD:279708 41/217 (19%)
ZnMc_astacin_like 122..300 CDD:239807 39/209 (19%)
ShK 367..404 CDD:279838 12/48 (25%)
ShK 414..450 CDD:279838
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3714
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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