DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cubn2 and LOC1276813

DIOPT Version :10

Sequence 1:NP_729748.3 Gene:Cubn2 / 39334 FlyBaseID:FBgn0259140 Length:3613 Species:Drosophila melanogaster
Sequence 2:XP_316205.3 Gene:LOC1276813 / 1276813 VectorBaseID:AGAMI1_012250 Length:286 Species:Anopheles gambiae


Alignment Length:217 Identity:42/217 - (19%)
Similarity:70/217 - (32%) Gaps:94/217 - (43%)


- Green bases have known domain annotations that are detailed below.


  Fly  1005 LGPTPSISIYD--------------NSTSPGKLVNSYSGS----------VGDVFDGDLLTINLH 1045
            ||.:..|..||              :..:.|:||.::|.|          :|...:||:      
Mosquito    24 LGSSRRIRDYDFDFSHLGEALYGNHDKAAIGELVRAWSRSHNGSSVNPEELGTYAEGDI------ 82

  Fly  1046 TNWPRLEIYSIQFDIVQQDSCGGTFTARFGYIKSPNWPKNYGESQMCEWI-------LRAPFG-- 1101
             :.|.:|..:::|                   .|..|.|.....:..|..       |.:.|.  
Mosquito    83 -HQPLIERNALKF-------------------TSSKWKKGIVPYEFSEEFSIGDLTKLFSAFEQF 127

  Fly  1102 HR---IELVVHNFTLEEEY-----SSTGCWTDWLEIRNGDSESSPLIGRYCGNEIPSR-----IP 1153
            |:   |..|.|  |.|.:|     .|:|||:              .:||..|.::.:.     :.
Mosquito   128 HQKTCIRFVPH--TKERDYVVIEGRSSGCWS--------------AVGRMGGRQVLNLQRNGCLQ 176

  Fly  1154 SFGNVLHLKFKSDDSMEEKGFL 1175
            ..|.::|      :.|...|||
Mosquito   177 MEGTIVH------ELMHALGFL 192

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cubn2NP_729748.3 cubilin_NTD 38..141 CDD:412063
EGF_CA 156..190 CDD:238011
EGF_CA 192..233 CDD:238011
EGF_CA 290..328 CDD:214542
EGF_CA 330..374 CDD:214542
EGF 427..455 CDD:394967
EGF_CA 462..496 CDD:238011
CUB 503..619 CDD:238001
CUB 624..738 CDD:238001
CUB 745..854 CDD:238001
CUB 857..963 CDD:238001
CUB 1066..1179 CDD:238001 26/132 (20%)
CUB 1185..1293 CDD:238001
CUB 1303..1406 CDD:238001
CUB 1411..1523 CDD:238001
CUB 1530..1648 CDD:238001
CUB 1754..1862 CDD:238001
CUB 1979..2091 CDD:238001
CUB 2210..2321 CDD:238001
CUB 2327..2441 CDD:238001
CUB 2688..2782 CDD:412131
CUB 2810..2911 CDD:238001
CUB 3029..3143 CDD:238001
CUB 3169..3249 CDD:412131
CUB 3499..3607 CDD:238001
LOC1276813XP_316205.3 ZnMc_astacin_like 101..283 CDD:239807 24/114 (21%)
Blue background indicates that the domain is not in the aligned region.

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