DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG42255 and mfrp

DIOPT Version :9

Sequence 1:NP_729748.3 Gene:CG42255 / 39334 FlyBaseID:FBgn0259140 Length:3613 Species:Drosophila melanogaster
Sequence 2:XP_009289590.1 Gene:mfrp / 101885305 ZFINID:ZDB-GENE-160728-150 Length:572 Species:Danio rerio


Alignment Length:602 Identity:132/602 - (21%)
Similarity:224/602 - (37%) Gaps:157/602 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly  1030 SVGDVFDGDLLTINLHTNWPRLE-IYSIQFDIVQQD----SCGGTFTARFGYIKSPNWPKNYGES 1089
            |..|.:.|:.::.||..:...|: .||....:...:    .|||..:...|.:.|||.|..|...
Zfish    97 SPSDTWFGNRVSENLSLSPTALQPTYSPTVSVSGTEPTFTKCGGMLSGAGGTLSSPNHPGVYPPD 161

  Fly  1090 QMCEWILRAPFGHRIELVVHNFTLEEEYSSTGCWTDWLEIRNGDSESSPLIGRYCGNEIPSRIPS 1154
            ..|.|::|......:::.|.:..:|   ..:.|..||||:|. ::|.:....|:|||..|..:.:
Zfish   162 SHCVWVIRVSPPSLVQIQVSSLAIE---GPSPCLFDWLEVRE-ETEKTSAATRFCGNVAPPTLNT 222

  Fly  1155 FGNVLHLKFKSDDSMEEKGFLLSWQQMGAGCGGKLSSSMGTIHSPHLLAGNRGILACDWQIIVAE 1219
            ..:.:.:.|.||.|:...||:..:                  ||  :|.|.|   :|..:..:.:
Zfish   223 NSSTVLVSFHSDGSIGGTGFIAQY------------------HS--ILPGQR---SCSREEFMCD 264

  Fly  1220 GSRVSLQLRSNDNRICSGQLTLYDGPTTASNPIVIRCNGTIAKPLQSTGNRVLVRYDVGHDAPDG 1284
            .....|.:     .||.||      |....:...:.|         |..:||             
Zfish   265 SGHCLLPV-----FICDGQ------PNCQDHSDELNC---------SHKHRV------------- 296

  Fly  1285 TDFMLNYQTNCRVRLEGLQGAIETPNFPENYPPGQDCEWDIRA-GGRKNHLQLIFSHLSVEKFSS 1348
                      |..::.|..|::.:||.|:.||..|.|.|.|.. .|:.  ::|.|.:.|:|. ..
Zfish   297 ----------CGGQITGEYGSLSSPNHPKPYPHQQMCTWQISVEDGQV--IRLSFQNFSLEA-QD 348

  Fly  1349 ICLNDYVSLVDMLDDQTLSEQHLCTNDGLEP-ITTVGNRLLLRFKSDSSVELQGFRAEYKRIGCG 1412
            :|..||   |::.|....:....| ...|.| :|:.|..|.:.|.:|..|...||.|.::.|...
Zfish   349 VCKFDY---VEVYDGAETALGRYC-GSALPPDLTSSGPVLTVVFVADEGVADSGFYASFQAISLS 409

  Fly  1413 EHLRESGGRFESPNAPFSVDMDCV---WII----TASEGNQIRLLLHEVY------FEAPQIE-C 1463
            |... |..:|..|..      :|:   |:.    ..::|......::..|      .|..|:| |
Zfish   410 ERTC-SPAQFACPTG------ECLHQDWLCDGWSDCADGADEHHCMNSTYPPFTSSCELIQVEMC 467

  Fly  1464 RDAESSLSVSAPSGYNSSVVLFRSCHEETQTQTFTSPGNELVIRFVSSSAPSRKYFKASFVQVPA 1528
            ||...:|: |.|:       ::.|..::.:..:.......||      ..|..:.|:      ..
Zfish   468 RDLSYNLT-SFPN-------IWLSLSDQREAASILHKYRVLV------DLPCFESFR------QL 512

  Fly  1529 SCGGYI---SASSGVLTTPGFHNHQDSKNVANYTSNIECVWTVEVTNGYGIRPHFEQFNLTDSGN 1590
            .||.::   |..||||        |..::|.: |:.::|            .|....|:|....|
Zfish   513 VCGMFLPRCSPQSGVL--------QLCQSVCS-TAELQC------------SPALSLFSLNWPFN 556

  Fly  1591 CSVSFVELTKLEPDNKE 1607
            |        .|.||:.:
Zfish   557 C--------LLLPDSHD 565

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG42255NP_729748.3 EGF_CA 156..190 CDD:238011
EGF_CA 192..233 CDD:238011
EGF_CA 290..328 CDD:214542
EGF_CA 330..374 CDD:214542
EGF 427..455 CDD:278437
EGF_CA 462..496 CDD:238011
CUB 503..619 CDD:238001
CUB 624..738 CDD:238001
CUB 745..854 CDD:238001
CUB 857..963 CDD:238001
CUB 1066..1179 CDD:238001 32/112 (29%)
CUB 1185..1293 CDD:238001 16/107 (15%)
CUB 1303..1406 CDD:238001 32/104 (31%)
CUB 1411..1523 CDD:238001 22/125 (18%)
CUB 1530..1648 CDD:238001 19/81 (23%)
CUB 1754..1862 CDD:238001
CUB 1979..2091 CDD:238001
CUB 2096..2193 CDD:294042
CUB 2210..2321 CDD:238001
CUB 2327..2441 CDD:238001
CUB 2688..2782 CDD:294042
CUB 2810..2911 CDD:238001
CUB 3029..3143 CDD:238001
CUB 3169..3249 CDD:294042
CUB 3499..3607 CDD:238001
mfrpXP_009289590.1 CUB 138..248 CDD:238001 32/131 (24%)
LDLa 256..290 CDD:238060 7/44 (16%)
CUB 297..405 CDD:238001 34/114 (30%)
LDLa 413..447 CDD:238060 6/40 (15%)
Fz 459..563 CDD:279700 32/152 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4292
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.900

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