Protein Alignment CG10361 and HEM1

DIOPT Version :9

• Sequence 1: NP_648509.1
• Gene: CG10361 / 39333
• FlyBaseID: FBgn0036208
• Length: 417
• Species: Drosophila melanogaster
• Sequence 2: NP_010518.1
• Gene: HEM1 / 851818
• SGDID: S000002640
• Length: 548
• Species: Saccharomyces cerevisiae
• Alignment Length: 454
• Identity: 139/454 - (30%)
• Similarity: 222/454 - (48%)
• Gaps: 72/454 - (15%)

  Fly    17 HYSAAAQAQLREILGTQLAGIKDAGTFKAERIITSSQSTQITVQGSDK----------------- 64
            |.:|||.|....  .||.:|      |..|.:|.|    ::..:..||
Yeast    53 HAAAAAAAAANH--STQESG------FDYEGLIDS----ELQKKRLDKSYRYFNNINRLAKEFPL 105

  Fly    65 --------KILNFCANNYLGLANNPEIVEHSQKLLEQYGAGLSSVRFICGTQDIHKQLEKKIAQF 121
                    |:..:|:|:||.|:.:||:::...|.:::||.|....|.|.|.......||.::|..
Yeast   106 AHRQREADKVTVWCSNDYLALSKHPEVLDAMHKTIDKYGCGAGGTRNIAGHNIPTLNLEAELATL 170

  Fly   122 HGREDTILYASCFDANAGIFEAILT------PEDAVFSDELNHASIIDGIRLCKAKKQRYRHRDL 180
            |.:|..::::||:.||    :|:|:      .:..:|||||||||:|.||:....||..::|.||
Yeast   171 HKKEGALVFSSCYVAN----DAVLSLLGQKMKDLVIFSDELNHASMIVGIKHANVKKHIFKHNDL 231

  Fly   181 GDLEEQLKASDARL-KLIATDGVFSMDGNIAPLARIVELARKYNALVFVDECHATGFFGATGRGT 244
            .:||:.|::....: ||||.:.|:||.|::|.:.:|.:||.||.||.|:||.||.|.:|..|.|.
Yeast   232 NELEQLLQSYPKSVPKLIAFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGV 296

  Fly   245 EEY----------------------DNVMGEVDIINSTLGKALGGASGGYTTGPAELISFLRQKS 287
            .|:                      ..||..||:|..||||:.|.. |||.....:||.:.|..:
Yeast   297 AEHCDFESHRASGIATPKTNDKGGAKTVMDRVDMITGTLGKSFGSV-GGYVAASRKLIDWFRSFA 360

  Fly   288 RPYLFSNTLPPAVVAVGLKVMDMLLQSSELTQRVQSNTQRFRQAMTKAGFTIAGENHPICPVMLG 352
            ..::|:.||||:|:|.....:.......:|....|.:|...::|..:.|..:......|.||::|
Yeast   361 PGFIFTTTLPPSVMAGATAAIRYQRCHIDLRTSQQKHTMYVKKAFHELGIPVIPNPSHIVPVLIG 425

  Fly   353 DARLASQFADEMLTR-GIYVIGFSYPVVPQGKARIRVQISAAHTEAEIDRAINAFIEVGRSLKV 415
            :|.||.|.:|.::.: .|||...::|.|.:|..|:|:..:..||....|..|||..:|...|::
Yeast   426 NADLAKQASDILINKHQIYVQAINFPTVARGTERLRITPTPGHTNDLSDILINAVDDVFNELQL 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10361	NP_648509.1	PRK06939	19..416	CDD:235893	138/452 (31%)
		BioF	30..410	CDD:223234	132/434 (30%)
HEM1	NP_010518.1	5aminolev_synth	71..492	CDD:273820	131/428 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0156
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1027
OMA	1	1.010	-	-		QHG58214
OrthoFinder	1	1.000	-	-		FOG0000902
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100359
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R554
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.700