Protein Alignment Gcat and Alas2

DIOPT Version :10

• Sequence 1: NP_648509.1
• Gene: Gcat / 39333
• FlyBaseID: FBgn0036208
• Length: 417
• Species: Drosophila melanogaster
• Sequence 2: XP_038955432.1
• Gene: Alas2 / 25748
• RGDID: 2084
• Length: 593
• Species: Rattus norvegicus
• Alignment Length: 361
• Identity: 130/361 - (36%)
• Similarity: 212/361 - (58%)
• Gaps: 11/361 - (3%)

  Fly    64 KKILNFCANNYLGLANNPEIVEHSQKLLEQYGAGLSSVRFICGTQDIHKQLEKKIAQFHGREDTI 128
            |.:..:|:|:|||::.:|.:::..::.|:.:|||....|.|.||...|.:||:::|:.|.::..:
  Rat   195 KDVSVWCSNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELEQELAELHHKDSAL 259

  Fly   129 LYASCFDAN-AGIFE-AILTPEDAVFSDELNHASIIDGIRLCKAKKQRYRHRDLGDLEEQLKASD 191
            |::|||.|| :.:|. |.|.|...::||..||||:|.|||...|.|..:||.|.|.|::.|:.||
  Rat   260 LFSSCFVANDSTLFTLAKLLPGCEIYSDAGNHASMIQGIRNSGAVKFVFRHNDPGHLKKLLEKSD 324

  Fly   192 ARL-KLIATDGVFSMDGNIAPLARIVELARKYNALVFVDECHATGFFGATGRGTEEYDNVMGEVD 255
            .:. |::|.:.|.||||.|.||..:.::|.:|.||.||||.||.|.:|..|.|..|.|.:|.::|
  Rat   325 PKTPKIVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVHAVGLYGTRGAGIGERDGIMHKLD 389

  Fly   256 IINSTLGKALGGASGGYTTGPAELISFLRQKSRPYLFSNTLPPAVVAVGLKVMDMLL--QSSELT 318
            ||:.|||||. |..|||.....:|:..:|..:..::|:.:|||.|::..|:.:.:|.  :...|.
  Rat   390 IISGTLGKAF-GCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALR 453

  Fly   319 QRVQSNTQRFRQAMTKAGFTIAGENHPICPVMLGDARLASQFADEMLTR-GIYVIGFSYPVVPQG 382
            :..|.|.:..||.:...||.:......|.|:.:|:|.|.|:..|.:|.: .|||...:||.||:|
  Rat   454 RAHQRNVKHMRQLLMDRGFPVIPCPSHIIPIRVGNAALNSKICDLLLAKHSIYVQAINYPTVPRG 518

  Fly   383 KARIRVQISAAHT----EAEIDRAINAFIEVGRSLK 414
            :..:|:..|..|:    |..:::.:.|:.|||..|:
  Rat   519 EELLRLAPSPHHSPQMMENFVEKLLLAWTEVGLPLQ 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gcat	NP_648509.1	PRK06939	19..416	CDD:235893	130/361 (36%)
Alas2	XP_038955432.1	Preseq_ALAS	5..100	CDD:462658
		5aminolev_synth	149..554	CDD:273820	129/359 (36%)