Protein Alignment Gcat and GCAT

DIOPT Version :10

• Sequence 1: NP_648509.1
• Gene: Gcat / 39333
• FlyBaseID: FBgn0036208
• Length: 417
• Species: Drosophila melanogaster
• Sequence 2: XP_016884163.1
• Gene: GCAT / 23464
• HGNCID: 4188
• Length: 521
• Species: Homo sapiens
• Alignment Length: 509
• Identity: 271/509 - (53%)
• Similarity: 324/509 - (63%)
• Gaps: 104/509 - (20%)

  Fly     6 KSLLFRGVGGRHYSAAAQAQLREILGTQLAGIKDAGTFKAERIITSSQSTQITVQGSD------- 63
            ::.||....||. :.:|.||||.||..:|.||:.|||:|:||:|||.|...|.|.|..
Human     8 RAALFWVPRGRR-AQSALAQLRGILEGELEGIRGAGTWKSERVITSRQGPHIRVDGVSGGPGTVI 71

  Fly    64 -------------------KKILNFCANNYLGLANNPEIVEHSQKLLEQYGAGLSSVRFICGTQD 109
                               ..||||||||||||:::||:::...:.||::||||||||||||||.
Human    72 FPGLPLPHLSCCIHLLSFTSGILNFCANNYLGLSSHPEVIQAGLQALEEFGAGLSSVRFICGTQS 136

  Fly   110 IHKQLEKKIAQFHGREDTILYASCFDANAGIFE-------------------------------- 142
            |||.||.|||:||.|||.|||.||:|||||:||
Human   137 IHKNLEAKIARFHQREDAILYPSCYDANAGLFESRALVQPGTETRGPQREAQNTLPLYPEERPGW 201

  Fly   143 ------------------------------AILTPEDAVFSDELNHASIIDGIRLCKAKKQRYRH 177
                                          |:|||||||.||||||||||||||||||.|.||||
Human   202 QYSFLICWSPGQGRSPGWLNDGSTLTASLQALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRH 266

  Fly   178 RDLGDLEEQL-KASDARLKLIATDGVFSMDGNIAPLARIVELARKYNALVFVDECHATGFFGATG 241
            .|:.|||.:| :|...||:|:||||.|||||:||||..|..||.:|.||||:||||||||.|.||
Human   267 LDMADLEAKLQEAQKHRLRLVATDGAFSMDGDIAPLQEICCLASRYGALVFMDECHATGFLGPTG 331

  Fly   242 RGTEEYDNVMGEVDIINSTLGKALGGASGGYTTGPAELISFLRQKSRPYLFSNTLPPAVVAVGLK 306
            |||:|...||.:|.|||||||||||||||||||||..|:|.|||::|||||||:||||||....|
Human   332 RGTDELLGVMDQVTIINSTLGKALGGASGGYTTGPGPLVSLLRQRARPYLFSNSLPPAVVGCASK 396

  Fly   307 VMDMLLQSSELTQRVQSNTQR--------------FRQAMTKAGFTIAGENHPICPVMLGDARLA 357
            .:|:|:.|:.:.|.:.:.|||              ||..|..|||||:|.:||||||||||||||
Human   397 ALDLLMGSNTIVQSMAAKTQRCDSQQGRLGGGETWFRSKMEAAGFTISGASHPICPVMLGDARLA 461

  Fly   358 SQFADEMLTRGIYVIGFSYPVVPQGKARIRVQISAAHTEAEIDRAINAFIEVGR 411
            |:.||:||.|||:||||||||||:|||||||||||.|:|.:|||.:.||:||||
Human   462 SRMADDMLKRGIFVIGFSYPVVPKGKARIRVQISAVHSEEDIDRCVEAFVEVGR 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gcat	NP_648509.1	PRK06939	19..416	CDD:235893	267/496 (54%)
GCAT	XP_016884163.1	AAT_I	27..520	CDD:450240	264/489 (54%)