Protein Alignment Klp68D and si:dkey-26i13.8

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_009304780.1
• Gene: si:dkey-26i13.8 / 797363
• ZFINID: ZDB-GENE-090312-134
• Length: 991
• Species: Danio rerio
• Alignment Length: 898
• Identity: 238/898 - (26%)
• Similarity: 399/898 - (44%)
• Gaps: 197/898 - (21%)

  Fly    22 VVVRCRPMSNRERSERSPEVVNVYPNRGVV------ELQNVVDGNKEQRKVFTYDAAYDASATQT 80
            |.:|.||::..|..|.:..|.:...|:.||      :..||:..::.:.|.:.:|.|:|.:|||.
Zfish    15 VALRIRPLNEAEIEEGATIVAHKIDNQMVVLMDPCEDSDNVLRAHRSREKTYMFDLAFDYTATQE 79

  Fly    81 TLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELMGIIPRTFEQIWLHI-NRTE 144
            .:|......|:..|:.|:|..:||||.||.|||.||.|:   |...||..||...::..| :.||
Zfish    80 DVYVATTKNLIDGVIAGYNATVFAYGPTGAGKTHTMLGL---DSEPGIYIRTLNDLFRAIEDSTE 141

  Fly   145 NFQFLVDVSYLEIYMEELRDLLKPNSKHLEVRERGSG-VYVPNLHAINCKSVEDMIKVMQVGNKN 208
            :....|.:||:|||.|.:||||.|:|.:||:||.|.| :.:..:...:..:.::::.::..|||.
Zfish   142 DLDCSVYMSYIEIYNEMIRDLLNPSSGYLELREDGKGEIRIAGITEFSTCNAKEIMALLTKGNKQ 206

  Fly   209 RTVGFTNMNEHSSRSHAIFMIKIEM---CDTETNTIKVGKLNLIDLAGSERQSKTGASAERLKEA 270
            ||...|..|:.|||||||..:.::.   .......::||||.::||||:||.|:|....:|:||.
Zfish   207 RTQESTAANKTSSRSHAILQVTVKQKSRVKDINEEVRVGKLFMVDLAGTERASQTQNRGKRMKEG 271

  Fly   271 SKINLALSSLGNVISALAE----SSPHVPYRDSKLTRLLQDSLGGNSKTIMIANIGPSNYNYNET 331
            :.||.:|.:|.|.|:||:|    .:..|.||||||||||:|:|||||:|:||.:|.|::.|:.|:
Zfish   272 AHINRSLLALANCINALSEKGGKGAQFVNYRDSKLTRLLKDALGGNSRTVMITHISPASSNFEES 336

  Fly   332 LTTLRYASRAKSIQNQPIKNEDPQDAKLKEY-------QEEIERLKRLIGPQQQQRSEKQVTAKK 389
            ..||.||.:||:|:.:..:|.......|.:|       :.|||||:..|    .|:|:.|:..:|
Zfish   337 RNTLVYADKAKNIRTKVKRNLMNVSYHLAQYTRIIADLRSEIERLRAKI----DQQSQDQLKGEK 397

  Fly   390 QRVKKPKKETVTKEMSDSLQVSTIEQPVEDDSDPEGAESESDKENEAEVAKSNEELERERVENSK 454
                                           :|....::|..:.:..|:|...|:|.....|..:
Zfish   398 -------------------------------ADIRNIQAEVQQYSHGEMALLQEQLLSAFREQME 431

  Fly   455 LAAKLAELEG---QL-VRGGKNLL--DTYSERQIELEKKLVEIAERKKREIEIQQQLELQEE--- 510
            :...|.|||.   :| :...::||  ..:...:....::..|::.:||...:.::|..:.||
Zfish   432 IRRSLMELENCNMELHIDTSRHLLTISDWERDRARARREKDELSGQKKHTDKEEEQESMPEEPQY 496

  Fly   511 ---------TTLEIRERNVSLEQEVE-------LKKRKLSKCYAKYLALQQELND-----CKSDH 554
                     ..|..:.:.:.|::|:|       ||..|:.:...|.:: ..|..|     ||
Zfish   497 VTAAREEIGPLLAEQRKTMELKRELEEKLLNMKLKSSKIEELLPKRIS-NTEQRDILMLLCK--- 557

  Fly   555 NQDLRELEMAQNELVKEL--KRQLLIIDNFVPIEVKQRLYTQAKYDEEQEEWKFSSMSLPTPPG- 616
               :.|||:.:.|:...:  |..:|...:|: |:..::..|.......|::.......|..|.|
Zfish   558 ---VHELELEKTEIQSAVLCKENVLRTKDFI-IQRHEQQRTLCDDIIHQQKMLIEDQGLCVPEGL 618

  Fly   617 -----------GDG---------KFSSKRPVSHPQRRRPTSEYALQEAKSNSPSSLRF------- 654
                       .||         .|::....:...|....|.  |:||.....|:::|
Zfish   619 QELYSLYFGELSDGIIDQILNLHTFTTNNLNARQLRLDVISN--LEEADKAEQSNVKFSPLDKHP 681

  Fly   655 --KSENIVNYELEMPCRTTQEYRT-PKV-------SASLQAVLAQAM------------QTGGDD 697
              .|.:.::|:.:    |.:.::: .|:       |:|.|.::.:..            ....|.
Zfish   682 RDSSSSGLDYDSD----TNRVFKSLSKIKPRRQHHSSSSQTLMRKVCAVKDSTPICPTESVSPDT 742

  Fly   698 IDIVDSHTNSL-------RSRLENIINANANGGAGPGAGV-------AVGSSIPN----VRNIKS 744
            :..:.|.|.|:       ||||:...|:.. .|.|..||:       ::.|::|:    ||....
Zfish   743 LREIVSDTKSISVIAAKRRSRLQAKSNSRM-AGMGLAAGLKSSVSMDSLVSTLPDESAEVRRSHQ 806

  Fly   745 SRGLPSAASNLDSNRRPPTGRLPAK------------------KP---ASAYP 776
            ..| .|:.|..|..|......||.|                  ||   ||.||
Zfish   807 RHG-GSSQSKQDPKRTEGRTELPEKQQHKKRSRSFEASKRQVQKPRQNASRYP 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	132/343 (38%)
		Smc	<431..>580	CDD:440809	36/180 (20%)
si:dkey-26i13.8	XP_009304780.1	KISc_KIP3_like	12..349	CDD:276821	131/336 (39%)