Protein Alignment Klp68D and kif15

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_073798386.1
• Gene: kif15 / 573988
• ZFINID: ZDB-GENE-050622-16
• Length: 1378
• Species: Danio rerio
• Alignment Length: 850
• Identity: 237/850 - (27%)
• Similarity: 379/850 - (44%)
• Gaps: 174/850 - (20%)

  Fly     1 MSAKSRRPGTGSSQTPNECVQVVVRCRPMSNRE-----------RSERSPEVVNVYPNRGVVELQ 54
            |:.|.:.....::.:..:.::|.||.||::...           .:..||:.|.::
Zfish     1 MNLKGKATAEANTNSDGDAIKVFVRVRPLTQGTGLSTDGDHSLCLTVSSPQTVRLH--------- 56

  Fly    55 NVVDGNKEQRKVFTYDAAYDASATQTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGV 119
                 .|.:.:.||||...|.:.:|..::..|...:|.|.:.|:||.||||||||:||||||.|.
Zfish    57 -----CKPEPRTFTYDHVADMNTSQEEVFSSVAKNIVESCMNGYNGTIFAYGQTGSGKTFTMLGP 116

  Fly   120 ----RGNDELMGIIPRTFEQIWLHINR-------TENFQFLVDVSYLEIYMEELRDLLKPNSKHL 173
                ..:|||.|:|||:||.::..|||       |::  ||...|::|||.|::.|||...|..|
Zfish   117 SELDNFSDELRGVIPRSFEYLFFLINREVERSGGTKS--FLCKCSFIEIYNEQIYDLLDSVSTSL 179

  Fly   174 EVRER-GSGVYVPNLHAINCKSVEDMIKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIKIEMCDT- 236
            .:||. ..||:|.........|..:..:|:.:|.:||.|..|:||..||||||:|.:.:|..:|
Zfish   180 FLREDIKRGVFVEGSVEKYAASAAEAYQVLSMGWRNRRVASTSMNRESSRSHAVFTMTLESKETG 244

  Fly   237 -ETNTIKVGKLNLIDLAGSERQSKTGASAERLKEASKINLALSSLGNVISALAESS----PHVPY 296
             |...|:..:|||:||||||||..|.....||||||.||.:|..||.||.||.:.|    .|:.|
Zfish   245 QEVVNIRTSQLNLVDLAGSERQRDTHTEGSRLKEASSINRSLMCLGQVIMALMDVSNGKNRHICY 309

  Fly   297 RDSKLTRLLQDSLGGNSKTIMIANIGPSNYNYNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKE 361
            ||||||.||:||||||:||.:|||:.|.:..:.|||:||::|.|||.|:|:.:.|||.| ..:::
Zfish   310 RDSKLTFLLRDSLGGNAKTYIIANVHPGSKCFGETLSTLQFAQRAKLIKNKAMVNEDTQ-GNVRQ 373

  Fly   362 YQEEIERLKRLIGPQQQQ----------------RSEKQVTAKKQ---------RVKKPKK---- 397
            .|.|:.:||..:.....|                :||.:|:.|.|         ::.:.||
Zfish   374 LQAEVRKLKEQLANALSQGRIVELAPTDATSGTDQSEPEVSYKTQFIQAMNFWKKIHEEKKALQQ 438

  Fly   398 -----ETVTKEMSDSLQVSTIEQPVEDDS---------------DPEGAESESDKENEAEV---- 438
                 |....:....:|.:.:.....||.               :||    |.:|:.:.|:
Zfish   439 KVSQLEAAWAQKEKFIQSNRMILKFRDDHIAQLKKELQTGQRSVEPE----ELNKQLQDEIRLLR 499

  Fly   439 --AKSNEELERERVENSKLAAKLAELEGQLVRGGKNLLDTYSERQIELEKKLVEIAERKKRE--- 498
              .:.|..:.|...||..|..::..|  :.:...|:.:::.::....|||..:::.|.:|.|
Zfish   500 DQVEHNPRMMRYAAENCSLREEIRAL--RALDSVKSAMESKAQSLTALEKTFLQLLEAQKTEDSN 562

  Fly   499 -----------------IEIQ----QQLELQEETTLEIRE----RNVSLEQEVELKKRKLSKCYA 538
                             :.::    |.|:.|.|.|..|:.    :.|:.:|..||:..:
Zfish   563 GAPPTYSTPVTMETLSSVSMERMKVQLLQKQSELTATIQAFEEFKEVTKKQVAELESER------ 621

  Fly   539 KYLA-----LQQELNDCKSDHNQDLRELEMAQNELVKEL---KRQLLIIDNFVPIEVKQRLYTQA 595
            :|..     |::.|...|:...|::.:|.....|.:|.|   .:...:.:..||:...:.|..||
Zfish   622 RYFEKSNKHLEKILEATKAHSKQEVSQLNKIHAETIKILTTPTKGYNLRNRLVPLSSPEHLNGQA 686

  Fly   596 KYDEEQEEWKFSSMSLPTPPGGDGKFSSKRPVSHPQRRRPTSEYAL--------QEAKSNSPSSL 652
                  ||.....:....||....:.:.:   :..:..:...|.||        :|||:......
Zfish   687 ------EEMDVDDIQNEQPPPEMNELACE---ALTEELKQMQEQALRVQGQLDEEEAKNRKLLQQ 742

  Fly   653 RFKSENIVNYELEMPCRTTQEYRTPKVSAS-----LQ---AVLAQAMQTGGDDIDIVDSHTNSLR 709
            ..|.|..|....|...||.|.:...:.|..     ||   ..|.|.:......:|::......||
Zfish   743 MSKLEEQVTIATEKSNRTEQMFGAERHSLQEEQERLQERIKTLEQQLDDEKGTMDVLQVEVRDLR 807

  Fly   710 SRLEN 714
            ..|::
Zfish   808 VVLQS 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	147/359 (41%)
		Smc	<431..>580	CDD:440809	34/190 (18%)
kif15	XP_073798386.1	None