Protein Alignment Klp68D and kif21b

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_073772347.1
• Gene: kif21b / 570502
• ZFINID: ZDB-GENE-130530-537
• Length: 1669
• Species: Danio rerio
• Alignment Length: 1013
• Identity: 262/1013 - (25%)
• Similarity: 402/1013 - (39%)
• Gaps: 324/1013 - (31%)

  Fly    15 TPNEC-VQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDGNKEQRKVFTYDAAYDASAT 78
            |.|:| |:|.:|.||...:|:.|......:|.|....|.|      .|:  |.||||..:|..|.
Zfish     3 TQNDCSVKVSLRIRPQMAKEKIEGCHICTSVTPGEPQVLL------GKD--KAFTYDFVFDLDAH 59

  Fly    79 QTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTME---GVRGNDELMGIIPRTFEQIWLHI 140
            |..:|...|..|:....||:|..:|||||||:|||:||.   .|..:::..|||||...|::..|
Zfish    60 QQQIYSACVHKLIEGCFEGYNATVFAYGQTGSGKTYTMGTGFDVSVSEDEQGIIPRAVHQLFQGI 124

  Fly   141 NRTE---------NFQFLVDVSYLEIYMEELRDLL--------KPNSKHLEVRERGS-GVYVPNL 187
            .:..         ...|.|...:||:|.||:.||.        :....::::.|.|| |:|...:
Zfish   125 QKRRLEAQSADIPPPDFKVSAQFLELYNEEILDLFDSTRDPEARGRKSNIKIHEDGSGGIYTTGV 189

  Fly   188 HAINCKSVEDMIKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIKI---------EMCDTETNTIKV 243
            .:....|.:::::.:::|..:||...|.||..||||||||.|.:         ::.:.|.|.:..
Zfish   190 TSRLVSSEDELLQCLKLGALSRTTASTQMNAQSSRSHAIFTIHLCQMRVCPQPQLVNGELNGVSD 254

  Fly   244 G------------KLNLIDLAGSERQSKTGASAERLKEASKINLALSSLGNVISALAESSP---H 293
            |            |.:.:|||||||..:|||:.||.:|...||..|.:||||||||.:.|.   |
Zfish   255 GSMSQSEYETLSAKFHFVDLAGSERLKRTGATGERAREGISINCGLLALGNVISALGDQSKRAGH 319

  Fly   294 VPYRDSKLTRLLQDSLGGNSKTIMIANIGPSNYNYNETLTTLRYASRAKSIQNQPIKNEDPQDAK 358
            ||||||||||||||||||||:|:|||.:.||:.::.|||.||:||:||::|:|:.|.|:|....:
Zfish   320 VPYRDSKLTRLLQDSLGGNSRTVMIACVSPSDRDFMETLNTLKYANRARNIKNKVIVNQDKTSQQ 384

  Fly   359 LKEYQEEIERL----------KRL----------------------------------------- 372
            :...:.||.||          ||:
Zfish   385 ISALRAEIARLQMEIMEYKAGKRVACDEGSEGFSDLFQENSMLQRENDTLRMRVKAMQETIDHLN 449

  Fly   373 ----------------------------------------------------------------- 372
                                                                             
Zfish   450 TRVTQLLTNGVNLLLTKTGETNEEIGNLIQNYIREIEELRSKLLESEAMNESLRRSLSRLSSRSV 514

  Fly   373 ----------IGPQQQQRSEKQVT----------------AKKQRVKKPKKETVTKEMS------ 405
                      ||.......|.::|                .:.||.|:|:||...|:.:
Zfish   515 YPSSHPSAPSIGSSPSVSMEAEMTDVIRQAKLDVERLKKKERNQRRKRPEKEKGLKKRAKLHPEE 579

  Fly   406 ------DSLQVSTIEQ------------------PV-EDDSDPEGAESESDKENEA---EVAKSN 442
                  :.|..:..|:                  |: |||....|.:.|.::|.|.   |...|:
Zfish   580 SGEKSENGLNRANEERRENGDGDSDNEPEEDGMYPLQEDDHGESGCDEEEEEEEETREEEEFDSD 644

  Fly   443 EEL---ERERVENSKLAAKLAELEGQLVRGGKNLLDTYSERQIELEKKLV-EIAERKKREIEIQQ 503
            |.|   :.:..|...|.|.||:|                ..:||::::|: |:...::|.:.::.
Zfish   645 ESLVDSDSDTDEKVNLQADLADL----------------TCEIEIKQRLIDELENSQRRLLTLKS 693

  Fly   504 QLE-----LQ---EETTLEIRER----NVSLEQEVELKKRKLSKCYAKYLALQQELNDCKSDHNQ 556
            |.|     ||   .:|.|| |:|    .:|:|...|.|..|:...|.|.|          .:.|:
Zfish   694 QYEEKLILLQNKIRDTQLE-RDRVLHNLMSMENYTEEKASKVKSEYEKRL----------KEMNR 747

  Fly   557 DLRELEMAQNELVKELK------RQLLIIDNFVPIEVKQRLYTQAKYDEEQEEWKFSSMSLPTPP 615
            ||.:|:.||.|..:.||      |:|..:.:.|....|.::....:..|||:..:..
Zfish   748 DLLKLQAAQKEHARLLKNQGRYERELKKLQSEVAEMKKAKVALMKQMKEEQQRRRMI-------- 804

  Fly   616 GGDGKFSSKRPVSHPQRRRPTSEY---ALQEAKSNSPSSLRFKSENIVNYELEMPCRTTQEYRTP 677
              |.|  ..|.::..::.:...||   ||:..|......||.|::.:.  .|....:...|....
Zfish   805 --DAK--RNREIAQLKKEQRRQEYQIRALESQKRQQELVLRRKTQEVT--ALRRLAKPLSERAAG 863

  Fly   678 KVSASLQAVLAQAMQTGGDDIDIVDSHTNSLRSRLENII---NANANGGAGPGAGVAVGSSIPNV 739
            :||..|.:|.:.| :..........|...|.|| :.:||   |...||..|     ...|..|
Zfish   864 RVSRRLTSVDSGA-ELSTSTTTTTSSEPESSRS-VSSIIRHWNTKLNGYLG-----ETDSHAP-- 919

  Fly   740 RNIKSSRGLPSAASNLDSNRRPPTGRLPAKKPASAYPK 777
                        |:|:.|:|:    :...|.|:|.:.|
Zfish   920 ------------AANMASSRK----KFQRKGPSSGFSK 941

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	144/375 (38%)
		Smc	<431..>580	CDD:440809	45/173 (26%)
kif21b	XP_073772347.1	None