Protein Alignment Klp68D and kif17

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001373250.1
• Gene: kif17 / 557863
• ZFINID: ZDB-GENE-080724-12
• Length: 823
• Species: Danio rerio
• Alignment Length: 863
• Identity: 302/863 - (34%)
• Similarity: 450/863 - (52%)
• Gaps: 187/863 - (21%)

  Fly    17 NECVQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDGNKEQRKVFTYDAAYDASATQTT 81
            :|.|:|||||||::|||::.....||:|........::...| .:|..|.||:|..|..:.:...
Zfish     3 SESVKVVVRCRPLNNREKAMNCKIVVSVDSTHCQCFIKKPGD-TEEPPKQFTFDGTYYINHSTEE 66

  Fly    82 LYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELMGIIPRTFEQIWLHINRTENF 146
            :|:|:.:|||..|.||:||.||||||||:||:|||:||.......|||||.||.|:..|...||.
Zfish    67 VYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGVPDPPSQRGIIPRAFEHIFETIQCAENT 131

  Fly   147 QFLVDVSYLEIYMEELRDLL-KPNSKHLEVRERGS-GVYVPNLHAINCKSVEDMIKVMQVGNKNR 209
            :|||..||||||.||:|||| |...:.:|::|... ||||.:|......||.:..:||.:|.:||
Zfish   132 KFLVRASYLEIYKEEIRDLLGKDIKQKMELKEHPERGVYVRDLTMQTVHSVGECERVMDLGWRNR 196

  Fly   210 TVGFTNMNEHSSRSHAIFMIKIEMCDTET---NTIKVGKLNLIDLAGSERQSKTGASAERLKEAS 271
            :||:|.||:.|||||:||.|.:|:|..:|   ..::.|||||:|||||||||||||:.:||:||:
Zfish   197 SVGYTLMNKDSSRSHSIFTIHLEICSIDTAGDEHLRAGKLNLVDLAGSERQSKTGATGDRLQEAT 261

  Fly   272 KINLALSSLGNVISALAES-SPHVPYRDSKLTRLLQDSLGGNSKTIMIANIGPSNYNYNETLTTL 335
            ||||:||:||||||||.:. |.::||||||||||||||||||::|:|:|.:.|::.||.|:::||
Zfish   262 KINLSLSALGNVISALVDGRSKYIPYRDSKLTRLLQDSLGGNTRTLMVACLSPADNNYEESISTL 326

  Fly   336 RYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKRLIGPQ------------------------ 376
            |||:|||||||:|..||||:||.|:||||||::|:.||..|
Zfish   327 RYANRAKSIQNRPRINEDPKDALLREYQEEIKKLRALISGQLGSGNLSSFLAGQKSGEASAVVSR 391

  Fly   377 -QQQRSEKQVTAKKQRVKK--------------PKKETVTKEMSDSLQVSTI------------- 413
             |...||.:  |:|.::|:              .::|:..|...|...:.|.
Zfish   392 PQSNTSESE--AEKDKIKEEYEKKLARLQAEYDAEQESKVKLQEDIAALRTSYETRLSSLERSRG 454

  Fly   414 ---------------EQPVE-----------DDSDPEGAESESDKENEAEVAKSNEELERERVE- 451
                           |:|:.           |.|:.|...|..|...:...:..::.|:...|:
Zfish   455 SRTHTTGGVHLQQHKEEPITASAASQEQAKIDHSESEERPSSVDATVKGAASGESQILDSVVVDI 519

  Fly   452 ----NSKLA-AKLAELEGQLVRGGKNLLDTYSERQIELEKKLVEIAERKKREIE-IQQQLELQEE 510
                :.||| .:|.:||.:.| ||:.:.:...:::.:..|.|.:  :|||:.|| :.|..|..:.
Zfish   520 PGQLDQKLALERLQQLEQEFV-GGEQVRNEELKQRHKQRKTLAD--QRKKQLIEALNQSSEDGDS 581

  Fly   511 TTLEIRERNVSLEQEVELKKRKLSKCYAKYLALQQELNDCKSDHNQDLRELEMAQNELVKELKR- 574
            ..|.:.:   |:::||..|.|.|.....|..|.:.|:.|.::       |.||.:|:.:..::|
Zfish   582 VLLNVYD---SIQEEVHAKSRHLENTQKKLKAAKLEIRDLQA-------EFEMERNDYLATIRRL 636

  Fly   575 ----QLL--IIDNFVPIEVK-------QRLYTQAKYDEEQEEWKFSSM-----SLP-TPPGG--- 617
                |||  |::..|.:..:       .||..:|.:|||...|:...:     :|| .||.|
Zfish   637 EREGQLLQGILERMVSLVRRDCNYSNLDRLRKEAVWDEEGGTWRLPDVLVQKTTLPAVPPSGVIA 701

  Fly   618 DGKFSSKRPVSHPQRRRPTSEYA---LQEAKSNSPSSLRFKSENIVNYELEMPCRTTQE-----Y 674
            .|:.|:        ||...|:.|   :||.:.:     |:|         ||..|:..|     |
Zfish   702 PGRLSA--------RRNSASDLADPFVQEEEQD-----RYK---------EMLNRSDSEHIATNY 744

  Fly   675 RTPKVSASLQAVLAQAMQTGGDDIDIVDSHTNSLRSRLENIINANANGGA---GPGAGVA---VG 733
            ..||.|:.|.|               .||..||:     |..::.:||.|   ..|:|::   |.
Zfish   745 FRPKRSSQLLA---------------TDSVKNSM-----NFSSSVSNGSAHQSSSGSGLSALTVE 789

  Fly   734 SSIPNVRNIKSSRGLPSA 751
            |.:|....:: |.|:|::
Zfish   790 SILPRPFRLE-SLGVPAS 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	178/336 (53%)
		Smc	<431..>580	CDD:440809	41/162 (25%)
kif17	NP_001373250.1	Motor_domain	4..335	CDD:473979	174/331 (53%)
		Smc	<398..>656	CDD:440809	56/272 (21%)