Protein Alignment Klp68D and Kif17

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_038967234.1
• Gene: Kif17 / 500571
• RGDID: 1562511
• Length: 1075
• Species: Rattus norvegicus
• Alignment Length: 1108
• Identity: 319/1108 - (28%)
• Similarity: 463/1108 - (41%)
• Gaps: 389/1108 - (35%)

  Fly    17 NECVQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQN--VVDGNKEQRKVFTYDAAYDASATQ 79
            :|.|:||||||||:.|||......||.|...||...:||  ..|   |..|.||:|.||......
  Rat     3 SESVKVVVRCRPMNKRERELNCQSVVTVDCARGQCFIQNPGAAD---EPPKQFTFDGAYYIEHFT 64

  Fly    80 TTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELMGIIPRTFEQIWLHINRTE 144
            ..:|:|:.:|||..|.||:||.||||||||:||:|||:|:.......|||||.||.::..:...|
  Rat    65 EQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPCQRGIIPRAFEHVFESVQCAE 129

  Fly   145 NFQFLVDVSYLEIYMEELRDLLKPNSK-HLEVRER-GSGVYVPNLHAINCKSVEDMIKVMQVGNK 207
            |.:|||..||||||.|::||||..::| .||::|. ..||||..|......:|....:||:.|.|
  Rat   130 NTKFLVRASYLEIYNEDVRDLLGADTKQRLELKEHPEKGVYVKGLSMHTVHNVAQCERVMETGWK 194

  Fly   208 NRTVGFTNMNEHSSRSHAIFMIKIEMCDTE---TNTIKVGKLNLIDLAGSERQSKTGASAERLKE 269
            ||.||:|.||:.|||||:||.|.||:...:   .:.::.|||||:|||||||||||||:.|||||
  Rat   195 NRAVGYTLMNKDSSRSHSIFTINIEIYAVDERGKDHLRAGKLNLVDLAGSERQSKTGATGERLKE 259

  Fly   270 ASKINLALSSLGNVISALAES-SPHVPYRDSKLTRLLQDSLGGNSKTIMIANIGPSNYNYNETLT 333
            |:||||:||:||||||||.:. ..|:||||||||||||||||||:||:|:|.:.|::.||:|||:
  Rat   260 ATKINLSLSALGNVISALVDGRCKHIPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLS 324

  Fly   334 TLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKRLI-------------------GP---- 375
            |||||:|||:|:|:|..||||:||.|:||||||:|||.::                   ||
  Rat   325 TLRYANRAKNIKNKPRINEDPKDALLREYQEEIKRLKAILAQQMGPGNLSALLSTQTPSGPVHPE 389

  Fly   376 ---------QQQQRSEKQ------------------------------VTA-------------- 387
                     ||...:|||                              :||
  Rat   390 EKLPSPTTVQQDTEAEKQMIREEYEERLARLKADYEAEQESRVRLQEDITAMRNSYDVKLSTLQE 454

  Fly   388 --KKQR---------------------VKKPKKETVTK-------------------EMSDSLQV 410
              :|::                     .|.|..|.|.|                   |.|..||.
  Rat   455 NLRKEKETGALCPGAAWEPTSCVPYTWAKGPLHEAVLKAEVLCKTEVMSRAEVTSGPEYSPPLQY 519

  Fly   411 STIEQPV---EDDSDPEG----------AESESDKENEAEVAKSNEE------------------ 444
            .|..:|.   ..|..|.|          :|..:.:.:.:||.:|||.
  Rat   520 ETAVKPTVLSMPDMLPRGEVTRSQAPLTSEEPNMEPSRSEVFESNESSNLEDSSMSEAYPGPEEL 584

  Fly   445 ------------------------------LERER-------VENSKLAAKL----AELEGQLVR 468
                                          ||.|.       :|..::.|.|    ||:|.:|.|
  Rat   585 SNVEFSMPGVLAESRYFPDEYLNPEAAGCPLEAEHSVQDEPTLEPLRILASLQDPFAEVEAKLAR 649

  Fly   469 -----------------------GGKNLL---DTYSERQI----------ELEKKLVE--IAERK 495
                                   ...:||   ||.||..:          :|..|:.|  ::|.:
  Rat   650 LSSTVAMTDLSQTVVPQVPQQQPSSTDLLEPSDTKSEVDVADNVLLRTEPDLSMKVAEEVVSEAE 714

  Fly   496 --------------------------------KRE---IEI-----------QQQ----LELQEE 510
                                            :||   :|:           |||    |:|.|:
  Rat   715 TGVWMESEAHVAHVAQVSEEAQPQPLLAMASVRRESIGVEVAVLTEELQPVDQQQVLARLQLLEQ 779

  Fly   511 TTL--------EIRER--------------------------------NV--SLEQEVELKKRKL 533
            ..:        :::|:                                ||  |:::||..|.:.|
  Rat   780 QVVGGEQAKNKDLKEKHRRRKRYADERKKQLVAALQNSDEDSGDWVLLNVYDSIQEEVRAKSKLL 844

  Fly   534 SKCYAKYLALQQELNDCKS-------DHNQDLRELE---MAQNELVKELKRQLLIIDNFVPIEVK 588
            .|...|..|.:.|:.|.:|       |:...:|..|   |...:|:::::..:....|:..:|
  Rat   845 EKMQKKLRAAEVEIKDLQSEFQLEKIDYLATIRRQERDSMLFQQLLEQVQPLIRRDCNYSNLE-- 907

  Fly   589 QRLYTQAKYDEEQEEWKF-------SSMSLPTPPGGDGKFSSKRPVSHPQRRR---PTSEYALQE 643
             ::..::.:||:...||.       :|:.:..|.|...|         |.|:.   .:.|..:||
  Rat   908 -KIRRESSWDEDNGFWKIPEPIILKTSLPVAVPTGTQNK---------PARKTSAVDSGEPHMQE 962

  Fly   644 AKSNSPSSLRFKSENIV-NYELEMPCRTTQEYRTPKVSASLQAVLAQAMQTGGDDIDIVDSHTNS 707
            .........|..||||. ||           :|:.:.|..|.....:::...    .:..:|. .
  Rat   963 EDRYKLMLSRSDSENIASNY-----------FRSKRASQILSTDPMKSLNCS----TLEPTHP-P 1011

  Fly   708 LRSRLENIINANANGGAGPGAGVAVGSSIPNVRNIKSSRGLPSAASNLDSNRRPPTGRLPAKKPA 772
            .|||     .:..|...|..:.::..|::|..:..:..:..|....:||.    |..:...||..
  Rat  1012 RRSR-----RSYHNSPPGLNSSLSNSSALPPAQTPEIPQPRPFRLESLDI----PFSKAKRKKSK 1067

  Fly   773 SAY 775
            |::
  Rat  1068 SSF 1070

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	183/338 (54%)
		Smc	<431..>580	CDD:440809	54/347 (16%)
Kif17	XP_038967234.1	Motor_domain	4..335	CDD:473979	181/333 (54%)