Protein Alignment Klp68D and Kif3C

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Alignment Length: 633
• Identity: 235/633 - (37%)
• Similarity: 346/633 - (54%)
• Gaps: 64/633 - (10%)

  Fly    17 NECVQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDGNKEQRKVFTYDAAYDASATQTT 81
            :|.::||||||||:..|:......:|.:  |...|.:.| ......|:|.|.:|:.|:.......
  Fly     2 SENIKVVVRCRPMNQTEKERNCQNIVEI--NEFAVSVTN-PSARISQQKKFIFDSVYNMKTDTEV 63

  Fly    82 LYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELMGIIPRTFEQIWLHINRTENF 146
            :|.|:.:.||.|.:||:||.||||||||.|||.||:|........||||:.|:.|:..|:.|.|.
  Fly    64 IYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERISMTTNV 128

  Fly   147 QFLVDVSYLEIYMEELRDLLKPNS-----KHLEVRERGSGVYVPNL---HAINCKSVEDMIKVMQ 203
            ::|..|:|||||.|.:||||..|.     .|......|.||.||.|   ..:|.....|.   :.
  Fly   129 RYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQCYDW---LH 190

  Fly   204 VGNKNRTVGFTNMNEHSSRSHAIFMIKIEMCDTETNTIKV--------GKLNLIDLAGSERQSKT 260
            .|||||....|.||::|||||.||.|.:|. ....|:|..        |||:|:||||||||.||
  Fly   191 FGNKNRVTAATLMNKNSSRSHTIFTITLEQ-SPFLNSIGSDAFGGICRGKLSLVDLAGSERQRKT 254

  Fly   261 GASAERLKEASKINLALSSLGNVISALAE-SSPHVPYRDSKLTRLLQDSLGGNSKTIMIANIGPS 324
            ||..:||||||:|||:||:||||||:|.: .:.|||:||||||||||||||||:||:||:.|.|:
  Fly   255 GAQGDRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISPT 319

  Fly   325 NYNYNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKRLIGPQQQQRSEKQVTAKK 389
            :.:|:||::|||||||||:|.|:|..||||:||:|::||.||..|||::  |:.|:...:.....
  Fly   320 DIHYDETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRML--QESQQIINKNNDPN 382

  Fly   390 QRVKKPKKETVTKEMSDSLQVSTIEQPVEDDSDPEGAESE-SDKENEAEVAKSNEELERERVENS 453
            :.:|.|.|......|:.:..|..|:.         |...: |.|.|.:.:.|.|..|.:.:.|..
  Fly   383 KIIKSPLKIIQHTNMNSTKNVQIIDL---------GRNCKASFKTNNSILTKPNFPLIQSKEEVQ 438

  Fly   454 KLAAKLAELEGQLVRGGKNLLDTYSERQIELEKKLVE---IAERKKREIEIQQQLELQEETTLEI 515
            ..|....:|..:.:.||:.:.|      .||::|.:.   .|:|....|.|.......|:..| :
  Fly   439 LQARSRIDLIKRSLIGGERIHD------FELKEKHMARKYAAQRHLSAIAIALSRVKCEDRDL-L 496

  Fly   516 RERNVSLEQEVELKKRKLSKCYAKYLALQQELNDCKSDHNQDLRE-LEMAQNELVKELK--RQLL 577
            :....::.||:::|...:.||..|...|:.|::|..|:...|..: |:..:| |.:::|  :||.
  Fly   497 QGHYATITQEIDIKNDYIRKCKEKIKMLEMEVSDLNSEFQLDREDYLDEIRN-LGRQVKFHQQLF 560

  Fly   578 I--------ID-NFVPIEVKQRLYTQAKYDEEQEEWKFSSMSL-PTPP 615
            :        .| |:.|..:.|    .:.::::.:.|:.....| ..||
  Fly   561 LKFSSNPGKFDRNWTPDTILQ----NSLWNDDLKMWRIPESDLIKLPP 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	165/347 (48%)
		Smc	<431..>580	CDD:440809	37/162 (23%)
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	163/342 (48%)