Protein Alignment Klp68D and neb

DIOPT Version :9

• Sequence 1: NP_001261726.1
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Alignment Length: 966
• Identity: 241/966 - (24%)
• Similarity: 404/966 - (41%)
• Gaps: 293/966 - (30%)

  Fly     4 KSRRPGTGSSQTP---------NECVQ--------VVVRCRPMSNRERSE-RSPEVVNVYPNRGV 50
            :::.||||.|...         ..|:.        |.||.||::..|.:. :...||.|:.|...
  Fly    88 RAKTPGTGKSSCSRTKERDSLMESCLSVSEESNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNE 152

  Fly    51 VELQ--NVVDGNKEQRKVFTYDAAYDAS-------ATQTTLYHEVVFPLVSSVLEGFNGCIFAYG 106
            :.:|  :..|.:......|:||..|.:.       |.|..::.....||:.:..||:|.|:||||
  Fly   153 LTVQAGSSADASAGVTHFFSYDQVYYSCDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYG 217

  Fly   107 QTGTGKTFTMEGVRGNDEL----------MGIIPRTFEQIWLHINRTENFQFL---VDVSYLEIY 158
            |||:||:::|.|:...|:.          .|||||...:::..|...::.|.|   |:|||.|||
  Fly   218 QTGSGKSYSMMGIEALDDAALDGGPPHDEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIY 282

  Fly   159 MEELRDLLKPNSKH---------------------LEVRERG-SGVYVPNLHAINCKSVEDMIKV 201
            .|::.|||  :.:|                     |:|||.. .|.||.:|.|.:..|...:...
  Fly   283 NEKIHDLL--SVQHAAAATGESTPIQQQQQQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNW 345

  Fly   202 MQVGNKNRTVGFTNMNEHSSRSHAIFMIKIEM----------CDTETNT------IKVGKLNLID 250
            :.|||..|....|.||:.|||||:||.|.:.:          .||:::|      .:..|::|:|
  Fly   346 LAVGNSQRATASTAMNDKSSRSHSIFNIVLNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVD 410

  Fly   251 LAGSERQSKTGASAERLKEASKINLALSSLGNVISALAES--------------SPHVPYRDSKL 301
            ||||||.|.:|::.||::|...||.:|.:||.||:|||:|              |..||||:|.|
  Fly   411 LAGSERISVSGSNGERIREGVSINKSLLTLGKVIAALADSRKAIANGPLGSGTPSTFVPYRESVL 475

  Fly   302 TRLLQDSLGGNSKTIMIANIGPSNYNYNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEI 366
            |.||:::|||||||:|:|.|.|::.:.:|||.|||||.:|:||.|:...||.|.|..:::.:.|:
  Fly   476 TWLLRENLGGNSKTVMLATISPASIHADETLATLRYACKARSIVNRVKVNESPHDKIIRDLRAEV 540

  Fly   367 ERLKRLIGPQQQQR--------------------SEKQVTAKKQRVKKPKKE--TVTKEMSDSLQ 409
            :|||.|....::||                    .|.:|.|.:|::.:.::|  ...|...:.|:
  Fly   541 DRLKSLRNEYERQRRLSGNSNNPVPRKIIIETSVDETEVEALRQQLAERERELSRAQKSWMEKLK 605

  Fly   410 VSTIEQPVEDDSDPEGAESESDKENEAEVAKSNE---ELERE----------------------- 448
                             |:|..:::|..|.|...   ||..|
  Fly   606 -----------------EAEDQRKSELRVLKRRGLALELTAEQKQACLVNLTADPILSGTLFYLL 653

  Fly   449 -----RVENSKLAAKLAE------LEGQLV----------RGGKNLL-------DTY-------S 478
                 |:...:|....:.      |:|.||          ||||..:       :||       .
  Fly   654 PQGLVRIGRGRLPGGSSSSQPDIVLDGPLVALQHCSIEHERGGKLYVIPGSEDFETYVNGELLKD 718

  Fly   479 ERQIELEKKLV------------EIAERKKREIEIQQQLELQEETTLEIRERNVSLEQEVELKKR 531
            .||:....:||            ..::|.|.:..:..||..||  .|:.:|:.:..|.|.| |:.
  Fly   719 RRQLFHGDRLVIGGSHYFRISNPFCSQRGKADHPVDFQLAHQE--ILQKQEQQLRSELEAE-KRA 780

  Fly   532 KLSKCYAKYLALQQELNDCKSDHNQDLRE----LEMAQ-----NELVKELKRQLLIIDNFVPIEV 587
            .|:|       ::||    ::.|.:|..|    ||:.|     |..:.|.:||.|.:       .
  Fly   781 ALTK-------IEQE----RAQHARDFEERLQCLELEQFKYKCNSEMLETERQALAL-------A 827

  Fly   588 KQRLYTQAKYDEEQEEWKFSSMSLPTP--------------PGGDGKFSSKRPVSHPQRRRPTSE 638
            :|:.:|..::::        ::|.|..              |..:....::..|....:|....:
  Fly   828 QQQEHTPLRHED--------AVSTPAQKSTILEDIQRIMLNPSEESLHKTQLMVKEATQRCRQLD 884

  Fly   639 YALQEAKSNSPSSLRFKSENIVNYELEMPCRTTQEYRTPKVSASLQAV--------------LAQ 689
            ..|:..::.:|.........|:..:.:...:.  |:.|.::...|..|              :.|
  Fly   885 LPLEFRQTQTPDEFGLLRTVILILDKQRGLKA--EWPTARLGVWLDLVRDNAEQQEKLNATTIFQ 947

  Fly   690 AMQTGGDDID------IVDSHTNS-------------LRSRLENIINANANGGAGP 726
            :::...:.:|      :.|:|.:|             |...|:.::||:::....|
  Fly   948 SVEVDWEPLDADLNETLSDTHNSSRIALNLSAMKDVLLNKPLKRLLNASSSKSNTP 1003

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_001261726.1	Motor_domain	18..344	CDD:277568	140/408 (34%)
		KISc	20..351	CDD:214526	142/413 (34%)
		GBP_C	<479..576	CDD:303769	29/117 (25%)
		coiled coil	547..558	CDD:293879	1/10 (10%)
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	142/407 (35%)
		KISc	120..525	CDD:214526	142/406 (35%)
		Kinesin_assoc	524..657	CDD:292801	26/149 (17%)
		FHA	634..740	CDD:238017	16/105 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437998
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940