Protein Alignment Klp68D and Kif16b

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_038960967.1
• Gene: Kif16b / 311478
• RGDID: 1310146
• Length: 1876
• Species: Rattus norvegicus
• Alignment Length: 862
• Identity: 260/862 - (30%)
• Similarity: 388/862 - (45%)
• Gaps: 219/862 - (25%)

  Fly    28 PMSNRERSERSPEVVNVYPNRGVVELQNVVDG-----NKEQRKVFTYDAAYDASATQTTLY--HE 85
            |||.:|:...:..::.:..::..:....:.:|     .:|:.|.||||.::.::.|::..|  .|
  Rat    15 PMSKQEKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTKSPDYVSQE 79

  Fly    86 VVF-----PLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELMGIIPRTFEQIWLHINRT-- 143
            .||     .:|.|..||:|.|:|||||||:||::||.|..|:.   |:|||..|.::..||.|
  Rat    80 TVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS---GLIPRICEALFSRINETTR 141

  Fly   144 -ENFQFLVDVSYLEIYMEELRDLLKPNSK---HLEVRER-GSGVYVPNLHAINCKSVEDMIKVMQ 203
             :...|..:|||||||.|.:||||:..|.   :|.|||. ..|.||.:|.....::..|:.::|.
  Rat   142 WDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYSDVEELMD 206

  Fly   204 VGNKNRTVGFTNMNEHSSRSHAIFMIKIEMC--DTETNTIKVGKLNLIDLAGSERQSKTGASAER 266
            .||.|||...|.||:.||||||||.||....  |.|.....|.|::|:|||||||...|||:..|
  Rat   207 AGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDAEMPCETVSKIHLVDLAGSERADATGATGVR 271

  Fly   267 LKEASKINLALSSLGNVISALAESSP------------HVPYRDSKLTRLLQDSLGGNSKTIMIA 319
            |||...||.:|.:|||||||||:.|.            .||||||.||.||:|||||||||||||
  Rat   272 LKEGGNINKSLVTLGNVISALADLSQDAANPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIA 336

  Fly   320 NIGPSNYNYNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKRLIGPQQQ------ 378
            .|.|::.||.|||:|||||:|||:|.|:|..|||.....::|.:.||.|||.|:....|
  Rat   337 TISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDS 401

  Fly   379 ---QRSEKQVTAKKQRVKKPKKETVTK--EMSDSLQVSTI-------------EQP----VEDDS 421
               ...|:::...:.||::..||...|  |..:.|:..|:             |.|    ::||.
  Rat   402 PTALSMEEKLHQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDL 466

  Fly   422 DPEGAESESDKENEAEVAKSNEELERERV-------------ENSKLAAKLAELEG--------- 464
            ...|......||.:..|.:.:...|::.|             ||:.....|..|.|
  Rat   467 LSTGIILYHLKEGQTYVGREDASTEQDIVLHGLDLESEHCVFENAGGTVTLIPLSGSQCSVNGVQ 531

  Fly   465 -----QLVRGGKNLLDTYSERQIELEKKLVEIAERKKR--------------------------- 497
                 ||.:|...||...:..:....|:..::.|::|.
  Rat   532 IVDATQLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSCENLSAVMLYN 596

  Fly   498 --------EIEIQQQLELQEETTLEIRERNVSLEQEVELKKRKLSKCYAKYLALQQELNDCKSDH 554
                    .|.::.:.|.|:...||..|....|.:|:| :|:|..|  |:...:|||:...:
  Rat   597 PGLFPMKGPICLRLEFERQQREELEKLESKRKLIEEME-EKQKSDK--AELERMQQEVETRR--- 655

  Fly   555 NQDLRELEMAQNELVKE---LKRQLLIIDNFVPIEVKQRLYTQAKYDEE-------------QEE 603
                :|.|:.|.::.|:   |||:...|:|    ::|..|..:.:::||             |||
  Rat   656 ----KETEIVQRQIRKQEESLKRRSFHIEN----KLKDLLAEKERFEEERLREQQGLEQQKRQEE 712

  Fly   604 WKFSSMSLPTPPGGDGKFSSKRPV-------SHPQ--RRRPTSE----YALQEAKSNSPSSLRFK 655
                          |..|..:..:       ||.|  :.:|..:    :..|:|:|   :.|:.:
  Rat   713 --------------DSFFRIREELRRLQELNSHEQAEKGQPLQDLDWLHREQDAQS---AKLQLE 760

  Fly   656 SENIVNYELEMPCRTT---QEYRTPKVSASL-------------------QAVLAQA--MQTGGD 696
            ...:...|.|...|..   ::.|..:.:|.|                   :..|.||  ::.|||
  Rat   761 KRRLEEQEKEQVLRVAHLEEQLRKRQDTAPLLCPGEAQQAQEERRELEGIRGALLQAKEIRAGGD 825

  Fly   697 DIDIVDSHTNSLRSRLE 713
                   ||  .|..||
  Rat   826 -------HT--FRGELE 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	158/355 (45%)
		Smc	<431..>580	CDD:440809	41/213 (19%)
Kif16b	XP_038960967.1	KISc_KIF1A_KIF1B	15..368	CDD:276816	158/355 (45%)
		Kinesin_assoc	367..479	CDD:465047	26/111 (23%)
		FHA	449..565	CDD:469597	21/115 (18%)
		Smc	<609..>1087	CDD:440809	58/265 (22%)