Protein Alignment Klp68D and KIF26A

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_056471.1
• Gene: KIF26A / 26153
• HGNCID: 20226
• Length: 1882
• Species: Homo sapiens
• Alignment Length: 414
• Identity: 109/414 - (26%)
• Similarity: 179/414 - (43%)
• Gaps: 72/414 - (17%)

  Fly    20 VQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDG-----------NKEQRKVFTYDAAY 73
            |:|::|..|....:||..:...:.|.|.:..|.|.:...|           .....|:|.:||.:
Human   372 VKVMLRIWPAQGAQRSAEAMSFLKVDPRKKQVILYDPAAGPPGSAGPRRAATAAVPKMFAFDAVF 436

  Fly    74 DASATQTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELMGIIPRTFEQIWL 138
            ...:.|..:....|..::.||:.|.:||||::|....||::||.|...:.:.:||:|....  ||
Human   437 PQDSEQAEVCSGTVADVLQSVVSGADGCIFSFGHMSLGKSYTMIGKDSSPQSLGIVPCAIS--WL 499

  Fly   139 ------HINRTENFQFLVDVSYLEI--YMEELRDLLKPNSKHLEVRERGSGVY----------VP 185
                  ...|| ..:|.|.||.:|:  ..:.|||||...:.......:..|||          :.
Human   500 FRLIEERRERT-GTRFSVRVSAVEVCGRDQSLRDLLAEVAPGSLQDTQSPGVYLREDPVCGAQLQ 563

  Fly   186 NLHAINCKSVEDMIKVMQVGNKNRTVGFTNMNEHSSR-SHAIFMI-----KIEMCDTETNTIKVG 244
            |...:...:.|.....:......|:.......|.:.| ||.:|.:     ::|.|.....:....
Human   564 NQSELRAPTAEKAAFYLDAALAARSTSRAGCGEDARRSSHMLFTLHVYQYRMEKCGRGGMSGGRS 628

  Fly   245 KLNLIDLAGSERQSKTGASAERLKEAS--KINLALSSLGNVISALAESSPHVPYRDSKLTRLLQD 307
            :|:||||...|      |:|.|..||:  .:.|:||:||:||.||...:.||||||.:||.||::
Human   629 RLHLIDLGSCE------AAAGRAGEAAGGPLCLSLSALGSVILALVNGAKHVPYRDHRLTMLLRE 687

  Fly   308 SLG-GNSKTIMIANIGPSNYNYNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKR 371
            ||. ...:|.|||::..:...:.|||:|::.|:|                         |.||:|
Human   688 SLATAGCRTTMIAHVSDAPAQHAETLSTVQLAAR-------------------------IHRLRR 727

  Fly   372 LIGPQQQQRSEKQVTAKKQRVKKP 395
            .........|..:.:.::.|.::|
Human   728 KKAKYASSSSGGESSCEEGRARRP 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	102/368 (28%)
		Smc	<431..>580	CDD:440809
KIF26A	NP_056471.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..66
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	149..201
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	316..337
		KISc	371..723	CDD:276812	102/384 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	729..785		3/23 (13%)
		PRK07764	<844..1285	CDD:236090
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	851..915
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	940..993
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1121..1237
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1335..1728
		PHA03307	1374..>1713	CDD:223039