Protein Alignment Klp68D and klp-18

DIOPT Version :9

• Sequence 1: NP_001261726.1
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_501093.1
• Gene: klp-18 / 177474
• WormBaseID: WBGene00002228
• Length: 932
• Species: Caenorhabditis elegans
• Alignment Length: 885
• Identity: 222/885 - (25%)
• Similarity: 381/885 - (43%)
• Gaps: 226/885 - (25%)

  Fly    73 YDASATQTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRG---NDELMGIIPRTFE 134
            :|:|::|..::..|...:|...:||:||.:|||||||:|||.||.|...   :.||||:|||:.|
 Worm    48 FDSSSSQEDVFGTVAKKIVEDCVEGYNGTVFAYGQTGSGKTHTMLGPCDSWTDQELMGLIPRSVE 112

  Fly   135 QIWLHIN----RTENFQFLVDVSYLEIYMEELRDLLKPNSKHLEVRERGSGVYVPNLHAINCKSV 195
            .::.|::    ..:...|.|.|.::|:|.|.:.|||...:| :::|:.|..:.:....:.|..:.
 Worm   113 HVFQHLDTKAKECQKLTFSVSVEFVELYNEVIYDLLNAKNK-VQLRDSGKDIQLVGALSKNVDNP 176

  Fly   196 EDMIKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIKIEMCDTETNTIKVGK-----LNLIDLAGSE 255
            .|::.::|.|.:.|:.|.|.||..||||||:.:|:|:   |:..|.::.|     |||:||||||
 Worm   177 LDLMHLVQKGWQERSTGSTAMNAESSRSHALLIIRIK---TQERTGELVKERSSILNLVDLAGSE 238

  Fly   256 RQSKTGASAERLKEASKINLALSSLGNVISALAESSP---HVPYRDSKLTRLLQDSLGGNSKTIM 317
            ||:.|.:|.:|||||:.||.:|:.||..|..||:.|.   |||||||.||.:|::||||||||.:
 Worm   239 RQTHTKSSGDRLKEATNINSSLTVLGRCIRLLADPSKAKGHVPYRDSHLTHILKNSLGGNSKTAV 303

  Fly   318 IANIGPSNYNYNETLTTLRYASRAKSIQNQPIKNE----DPQDAKLKEYQE-------------- 364
            |.|:.|......|:.:||.:|.....|.|...:||    |.:.:..|..||
 Worm   304 IVNMHPDRDFAQESNSTLMFAQSCTMIMNIATRNEVMTGDQESSYKKAIQELRQEVDETREKVRT 368

  Fly   365 ---------EIER-------------------------LKRLIGPQQQ----------------- 378
                     |:|:                         ||..||.:.:
 Worm   369 EFASQLDEAEVEQLRLKTENNSLRLENVDLRAKYDFALLKYTIGSENEQIVNEFKKIISEFSAAN 433

  Fly   379 ------------QRSEKQVTAKKQRVKKPKKET--VTKEMSDSLQVSTIEQPVEDDSDPEGAESE 429
                        |..:.::.|.::|.::.:|||  :.....::|..:.:   ::..|..|...|.
 Worm   434 SSSPFECIALKNQTLQLEIEASEKRYQELQKETSALRNRYQENLDATIL---MQTPSAKERRSSS 495

  Fly   430 SDKENE-------------AEVAKSNEELERERVENSKLAAKLAE------------------LE 463
            ..|..|             |||..|.:.:...:.:|.||:.:|:.                  |:
 Worm   496 RPKRRETQYRPSPARMALFAEVETSEDAVLDLQCQNEKLSCELSSLKDKHEEATSKSIETERLLQ 560

  Fly   464 GQLV-------------RGGKNLLDTYSER----QIELEKKLVEIAERKKR--EIEIQQQLELQE 509
            |::|             |..:.:.:.|.|:    .:.|:|.|:.|...:||  |:|:..: |.:.
 Worm   561 GEIVALQKEVSIVSESLRKSEAVAEGYKEKVTANNLTLDKLLLHIDASRKRIAELELSSK-ESEN 624

  Fly   510 ETTLEIRERNVSLEQEVELKKRKLSKCYAKYLALQQELNDCKSDHN---QDLRELEMAQNELVKE 571
            .::.|:.|:.:.....:|..:||.|.   :|.||::|||......|   ..:.||::: |..:|:
 Worm   625 RSSEELEEQRLYYVSMIEDLERKASD---EYAALREELNQKTLSSNLLQVQVDELQLS-NATIKK 685

  Fly   572 LKRQL-----LIIDNFVPIEVKQRLYTQAKYDEEQEEWKFSSMSLPTPPGGDGKFSSKRPVSHP- 630
            |...|     ||......||.|.::.|:.   |||.....|.:|           |:||.:.|.
 Worm   686 LNADLSTKAGLIRSLEDSIEKKSQMITRL---EEQAVLDSSELS-----------STKRQLEHSR 736

  Fly   631 ----QRRRPTSE--YALQ-------------------------------EAKSNSPSSLRFKSEN 658
                |.|:.:.|  .|:|                               .|:.....::..|.:|
 Worm   737 LEAIQWRKISEETTSAMQTQLKDHQKDIDQCRHKKKLEIQSMQLSLDNANARVKESEAMMKKLQN 801

  Fly   659 IVNYELEMPCRTTQEYRTPKVSASLQ----AVLAQAMQTGGDDIDIVDSHTNSLRSRLENIINAN 719
            ....:.:|.....:.....|:|.||:    .:..|::......::::::....|...:|::.:.:
 Worm   802 DEKQKFDMKMSEIENTFKEKLSVSLKKQEDTIRRQSLAENQGKLEVMENKNRVLSETIESLQSQH 866

  Fly   720 ANGGAGPGAGVAV-GSSIPNVRNIK-SSRGLPSAASNLDS 757
            :.......||:.. |..:..|..:: ..:.|....|.|.|
 Worm   867 SQDTEVINAGLRTRGDRVGYVDKLRVEKKALEETISQLRS 906

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_001261726.1	Motor_domain	18..344	CDD:277568	115/285 (40%)
		KISc	20..351	CDD:214526	117/292 (40%)
		GBP_C	<479..576	CDD:303769	28/105 (27%)
		coiled coil	547..558	CDD:293879	3/13 (23%)
klp-18	NP_501093.1	KISc	5..328	CDD:276812	115/283 (41%)
		SbcC	342..913	CDD:223496	103/587 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810