Protein Alignment Klp68D and Kifc5b

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_444403.2
• Gene: Kifc5b / 16580
• MGIID: 2137414
• Length: 672
• Species: Mus musculus
• Alignment Length: 300
• Identity: 119/300 - (39%)
• Similarity: 171/300 - (56%)
• Gaps: 32/300 - (10%)

  Fly    64 RKVFTYDAAYDASATQTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTME-GVRGNDELMG 127
            |..|::|..:...:.|..::.|:.. ||.|.|:|:..|||||||||:||||||| |.||:.:|.|
Mouse   368 RHDFSFDRVFPPGSKQEEVFEEIAM-LVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLAG 431

  Fly   128 IIPRTFEQIWLHINRT--ENFQFLVDVSYLEIYMEELRDLL-----KPNSKHLEVRERGSGV--- 182
            :|||....::......  :.:.:....||:|||.|.:||||     |......|:|....|.
Mouse   432 LIPRAMRHLFSVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGPRKGQGGECEIRRASPGSEEL 496

  Fly   183 ------YVPNLHAINC-KSVEDMIKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIKIEMCDTETNT 240
                  |||    ::| |.||   .::.:.::||.|..|..|:.|||||::|.::|. .:.....
Mouse   497 TVTNARYVP----VSCEKEVE---ALLHLAHQNRAVAHTAQNKRSSRSHSVFQLQIS-GEHAARG 553

  Fly   241 IKVG-KLNLIDLAGSERQSK----TGASAERLKEASKINLALSSLGNVISALAESSPHVPYRDSK 300
            ::.| .|||:|||||||...    .....:||:|...||.:||:||.||.||:....|||||:||
Mouse   554 LQCGAPLNLVDLAGSERLDPGLPLGPGERDRLRETQAINSSLSTLGLVIMALSNKESHVPYRNSK 618

  Fly   301 LTRLLQDSLGGNSKTIMIANIGPSNYNYNETLTTLRYASR 340
            ||.|||:||||::|.:|..||.|...|.:|:|.:||:||:
Mouse   619 LTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASK 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	119/299 (40%)
		Smc	<431..>580	CDD:440809
Kifc5b	NP_444403.2	SMC_prok_B	<144..306	CDD:274008
		KISc_C_terminal	307..664	CDD:276817	119/299 (40%)