Protein Alignment Klp68D and Kif13a

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_036013758.1
• Gene: Kif13a / 16553
• MGIID: 1098264
• Length: 1840
• Species: Mus musculus
• Alignment Length: 976
• Identity: 287/976 - (29%)
• Similarity: 414/976 - (42%)
• Gaps: 295/976 - (30%)

  Fly    20 VQVVVRCRPMSNRERSERSPEVVNVYPNRGVVE--LQNVVDGNKEQRKVFTYDAAY-DASATQTT 81
            |:|.||.|||:.||....:..||.:..|:.|:.  ..|...|.::..|||.:|..: ....:.||
Mouse     6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMDESNTT 70

  Fly    82 LY--HEVVFP-----LVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELMGIIPR----TFEQ 135
            .|  .||||.     ::....:|:|.|||||||||:||:|:|   .|:.|.:|:|||    .|::
Mouse    71 KYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSM---MGHAEQLGLIPRLCCALFQR 132

  Fly   136 IWLHINRTENFQFLVDVSYLEIYMEELRDLLKP--NSKHLEVRE-RGSGVYVPNLHAINCKSVED 197
            |.|..|.::.|:  |:|||:|||.|::||||.|  :.:.|:||| :..|.||..|..:...|.||
Mouse   133 IALEQNESQTFK--VEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLGPYVDGLSQLAVTSFED 195

  Fly   198 MIKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIKIEMCDTETNTI----------KVGKLNLIDLA 252
            :..:|..|||:|||..|||||.||||||:|.|.|      |.|:          ||.|::|:|||
Mouse   196 IESLMSEGNKSRTVAATNMNEESSRSHAVFNIII------TQTLYDLQSGNSGEKVSKVSLVDLA 254

  Fly   253 GSERQSKTGASAERLKEASKINLALSSLGNVISALAE------SSPHVPYRDSKLTRLLQDSLGG 311
            ||||.|||||:.|||||.|.||.:|::||.|||:||:      .:..||||||.||.||:|:|||
Mouse   255 GSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGKNKFVPYRDSVLTWLLKDNLGG 319

  Fly   312 NSKTIMIANIGPSNYNYNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKRLI--- 373
            ||:|.|||.|.|:..||.|||:|||||.|||.|.|..:.||||....::|.:||:|:|:..:
Mouse   320 NSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQA 384

  Fly   374 ----GPQQQQRSE------KQVTAKKQRVKKPKKETVTKE-------MSDSLQVSTIEQPVEDD- 420
                .|:.:::.|      |::|...:. |..|.|.:.:|       |..||:.|.|:  |.||
Mouse   385 EAMKAPELKEKLEESEKLIKELTVTWEE-KLRKTEAIAQERQRQLESMGISLETSGIK--VGDDK 446

  Fly   421 -------SDPE---------------GAESESD----------KENEAEVAKSNE------ELER 447
                   :||.               ||::..|          :..|.::|...:      |..|
Mouse   447 CYLVNLNADPALNELLVYYLKDHTRVGADTSQDIQLFGIGIQPEHCEIDIAADGDITLTPKENAR 511

  Fly   448 ERVENSKLAAKLAEL-EGQLVRGGKNL----------------------------LDTYSERQIE 483
            ..| |..|.....:| .|..:..|.|.                            ||..||...|
Mouse   512 SCV-NGTLVCSTTQLWHGDRILWGNNHFFRINLPKRKRRDWLKDFERETSSAEHDLDAASEASSE 575

  Fly   484 ------------------------------------------------LEKKLVEIAERKKREIE 500
                                                            .:.|||.....:.....
Mouse   576 PDYNYEFAQMEVIMKTLNSNGGFPIVSLSAWWSSPWWSYLKILFPLLWFQTKLVHQHWERDPVQN 640

  Fly   501 IQQQLELQ--EETTLEIRERNVSLEQEVELKKRKLSK------------CYAKYLALQQELNDCK 551
            :.|.||.|  ||....:.|:.:..|:|:|..:::||.            .|:...| ||::....
Mouse   641 VVQVLEKQYLEEKRTALEEQRLMYERELEQLRQQLSPERQPPSSASDRLAYSSQTA-QQKVTQWA 704

  Fly   552 SDHNQ-------DLRELEMAQNELVKELKRQLLIIDNFVPIEVKQRLYTQAKYDEEQEEWKFSSM 609
            .:.::       .|||..:..|.||:|.        ||:.              ||..:.....:
Mouse   705 EERDELFRQSLAKLREQLVKANTLVREA--------NFLA--------------EEMSKLTDYQV 747

  Fly   610 SLPTPPGGDGKFSSKRP----VSHP--QRRRP---TSEYAL--------------QEAKSNSPSS 651
            :|..|.   ...|:.|.    ||.|  |.||.   |..:.:              ||.|.|.|.:
Mouse   748 TLQIPA---ANLSANRKRGAIVSEPAIQARRKGKGTQVWTIEKLENKLIDMRDLYQEWKENVPEA 809

  Fly   652 LRF----------KSEN-----IVNYELE-MPCRTTQEYRTP------KVSASLQAVLAQAMQTG 694
            .|.          ..||     :.|..|| :.|....:|..|      :|:..|...:.:...|.
Mouse   810 KRLYGKRGDPFYEAQENHNLIGVANVFLECLFCDVKLQYAVPIISQQGEVAGRLHVEVTRITGTI 874

  Fly   695 GDDIDIVDSHTNSLRSRLENIINANANGGAGPGAGVAVGSSIPNVRN------IKSSRGLPSAAS 753
            .:.:...||..||..|....:::::             |..|..|:.      ||.:.|||.:.|
Mouse   875 PERMAEDDSSENSSESGSLEVVDSS-------------GEVIHRVKKLTCRVIIKEATGLPISLS 926

  Fly   754 N 754
            |
Mouse   927 N 927

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	168/363 (46%)
		Smc	<431..>580	CDD:440809	43/262 (16%)
Kif13a	XP_036013758.1	KISc_KIF1A_KIF1B	5..359	CDD:276816	168/363 (46%)
		Kinesin_assoc	356..468	CDD:465047	27/114 (24%)
		FHA_KIF13A	446..554	CDD:438781	16/108 (15%)
		SMC_prok_B	<646..>801	CDD:274008	36/180 (20%)
		KIF1B	788..832	CDD:463574	8/43 (19%)
		DUF3694	<1255..1319	CDD:463599