Protein Alignment Klp68D and Klp54D

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_061516746.1
• Gene: Klp54D / 1280785
• VectorBaseID: AGAMI1_004503
• Length: 868
• Species: Anopheles gambiae
• Alignment Length: 711
• Identity: 215/711 - (30%)
• Similarity: 333/711 - (46%)
• Gaps: 115/711 - (16%)

  Fly    10 TGSSQ----TPNECVQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDG-------NKEQ 63
            ||||.    ||.:.:.||||.||:||:| :....|:|..:|..|    |.:.||       ..::
Mosquito   174 TGSSNSMPGTPEDNINVVVRVRPLSNKE-ARHGDEMVVQFPGNG----QILCDGIPLTSGAGAQK 233

  Fly    64 RKVFTYDAAYDASATQ-TTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEG-----VRGN 122
            .|:|:|:..::..||| ..|.:..:..|:...:|||:...|.|||||:|||.|:.|     .|..
Mosquito   234 PKLFSYNVVFEPGATQDDVLQYSGIKRLIEMAIEGFSCTAFCYGQTGSGKTHTLTGPPELFYRKP 298

  Fly   123 D---ELMGIIPRTFEQIWLHINRTENFQFLVDVSYLEIYMEELRDLLKPNS--KHLEVR--ERGS 180
            |   |..|::.|:|..::..:...::..|::..|:||||.|::.|||.|.:  |.|.||  ::..
Mosquito   299 DPAHEDHGLVFRSFLYLFKLLQERKDTNFVLKASFLEIYNEKVIDLLNPGTARKPLAVRWSKKSR 363

  Fly   181 GVYVPNLHAINCKSVEDMIKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIKI---EMCDTETNTIK 242
            |.:|.||..::|:.::|::.|::.|.:||.||...||::|||||.|..:.|   :..:......|
Mosquito   364 GFFVENLFTVDCEELDDLLAVLEEGMRNRHVGSHLMNDYSSRSHTILTVHITSEQQAEGGVFISK 428

  Fly   243 VGKLNLIDLAGSERQSKTGASAERLKEASKINLALSSLGNVISALAES---SPHVPYRDSKLTRL 304
            .||:|.:||||||...||.:..:.|:||:.||.:|..||..|::|::|   ..|:||||||||:|
Mosquito   429 QGKINFVDLAGSEMTKKTHSEGKTLEEANNINKSLMVLGYCIASLSDSKRRGGHIPYRDSKLTKL 493

  Fly   305 LQDSLGGNSKTIMIANIGPSNYNYNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERL 369
            |.|||.||..|:|||.|.|:..|..||:.|||||:|||.|:.:||...||::|.       |..|
Mosquito   494 LADSLAGNGVTLMIACISPAQSNVTETVNTLRYAARAKRIRTKPIIVMDPREAL-------ILSL 551

  Fly   370 KRLIGPQQQQRSEKQVTAKKQRVKKPKKETVTKEMSDSLQVSTIEQ----------PVEDDSDPE 424
            ||.||..|.:....:.....|          |:....:.||..:|:          .||..:|.|
Mosquito   552 KREIGALQVENEHLRTALNLQ----------TEAQDINSQVDLLERRPIPRSPPKVDVEKLTDME 606

  Fly   425 G-----------AESESDKENEAEVAKSNEELERERV----ENSKLAAKLAELEGQLVRGGKNLL 474
            |           .|:::.::..||:..:.|.:.|::.    ||.:|..||.::.....|  ..::
Mosquito   607 GNELKELVKVYVTENQALRQENAELYSTREMIIRDQELVCRENERLLKKLEDVNSVCCR--SPII 669

  Fly   475 ---DTYSERQIELEKKLVEIAERKKREIEIQQQLELQEETTLEIRERNVSLEQEVELKKRKLSKC 536
               .|:|...:.|.      |.....|:....:..|........|.||.||:..|...:.|:.:
Mosquito   670 PARPTFSAEMLNLS------AASGDLEVSNIWRNPLSSSADSMNRYRNESLDGRVSANENKIPE- 727

  Fly   537 YAKYLALQQELNDCKSDHNQDLRELEMAQNELVKELKRQLLIIDNFVPIEVKQRLYTQAKYDEEQ 601
                 .||:||     |..:....:....|.|.:..........|...:...:....:...|...
Mosquito   728 -----LLQKEL-----DKRRIGDSITTIANNLTRNNSWDTANRSNGTSMHGMKLASRKGSADSRH 782

  Fly   602 EEWKFSSMS-------LPTPPGGDGKFSSKRPVSHPQRRR--PTSEYALQEAKSNSPSSLR 653
            .:...:..|       .|.||    :.:.....|||..||  |.|..|   .||.:|.|:|
Mosquito   783 SDPSQARTSQTRIIDLAPNPP----QTARSSAASHPPWRRSAPRSSSA---QKSATPLSVR 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	139/356 (39%)
		Smc	<431..>580	CDD:440809	30/155 (19%)
Klp54D	XP_061516746.1	None