Protein Alignment Klp68D and Klp31E

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_061516566.1
• Gene: Klp31E / 1278143
• VectorBaseID: AGAMI1_013230
• Length: 1675
• Species: Anopheles gambiae
• Alignment Length: 891
• Identity: 248/891 - (27%)
• Similarity: 375/891 - (42%)
• Gaps: 257/891 - (28%)

  Fly    16 PNE----CVQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDGNKEQRKVFTYDAAYDAS 76
            |:|    .|:|.||.||...||..:.......|.|....|.|.:        .|.||:|..:|.|
Mosquito     2 PDEDKESSVRVAVRIRPQIPRELIDMCRVCTQVTPGEPQVLLGS--------DKAFTFDYVFDMS 58

  Fly    77 ATQTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELM-----GIIPRTFEQI 136
            .||.::|:..:..||...|:|:|..:.||||||:|||:||.  .|.:..:     |||||....:
Mosquito    59 TTQVSVYNNCIEKLVDGALQGYNATVLAYGQTGSGKTYTMG--TGFERALPEAQEGIIPRAVRHL 121

  Fly   137 WLHINRTE------------NFQFLVDVSYLEIYMEELRDLLKPNSKHLEV----RERGSGVYVP 185
            :..|.:.:            ...|.|...::|:|.||:.|||.|.:|...|    .:...|:.|.
Mosquito   122 FEGIAQLQQNPYDEDGTYLGTVTFSVAAQFMELYNEEVIDLLDPYNKGARVFKIFEDATGGISVA 186

  Fly   186 NL---------HAINCKSVEDMIKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIKI--------EM 233
            ..         .|:||         :|.|...||...|.|||.||||||:|.|.|        |.
Mosquito   187 GATIKPLAGPQEALNC---------LQQGALARTTASTQMNEQSSRSHALFTILIRRQRVMTAEQ 242

  Fly   234 C-----DTETNTIKVGKLNLIDLAGSERQSKTGASAERLKEASKINLALSSLGNVISALAESS-- 291
            |     ||||.|   .|.:.:|||||||..:|||:.||.:|...||..|.:||||||||.:.:
Mosquito   243 CGNAEGDTETLT---SKFHFVDLAGSERLKRTGATGERAREGISINCGLLALGNVISALGDKTKK 304

  Fly   292 -PHVPYRDSKLTRLLQDSLGGNSKTIMIANIGPSNYNYNETLTTLRYASRAKSIQNQPIKNEDPQ 355
             .|||||||||||||||||||||:|||||.:.||:.::.|||.||:||:||::|:|:...|:|..
Mosquito   305 VSHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVQINQDQS 369

  Fly   356 DAKLKEYQEEIERLK-RLIGPQQQQRS--------------EKQVTAK-----KQRVKKPKKETV 400
            ...:...:.||..|: .::..:|.:||              |.::.::     :||| |..:||:
Mosquito   370 SRTISLLRREIANLQLEILEYKQGKRSIDADGNIAISDVSLENEMLSQDNKRLQQRV-KAMQETI 433

  Fly   401 T--KEMSDSLQV-STIEQPVEDDSDPEG---AESESDKENEAEVAKSNEELERERV-----ENSK 454
            .  .|.:.:||. .||....:..:..:|   |.|.::..:....|..|:...:|.:     |..|
Mosquito   434 NALTEKNAALQAQQTIASLHKASAAGDGGADATSTNNGSSPVGTAGGNDSAMQELIVGYISEIEK 498

  Fly   455 LAAKLAELEGQLVRGGK------------------------NLL--------------------- 474
            |.|||.|.|....:..|                        |:|
Mosquito   499 LKAKLIESEQMFQQFKKAKSSQSKLGIKTYPFIEDNPETMINMLKHEMEKERETLMSRSLPGLEH 563

  Fly   475 -------------DTYSE--------------RQIELEKKLVEIAERKKREIEI-QQQLE----- 506
                         ||.|:              ..|||:.:|:|..|..::.::| :||.|
Mosquito   564 ESSSMDQNSDSDSDTESDDKAEVLRAEMSDVNSDIELKVRLIEQLEESQQRLQIMRQQYEKQFNL 628

  Fly   507 LQEETTLEIRERNVSLE------------------QEVELKK------RKLSKCYAKYLALQQEL 547
            ::|:.:...|||:..|.                  .|..:|:      |||::       |:::|
Mosquito   629 MKEKISNTERERDEVLATIGNGGTGAMNNKGQNSGNETAIKRVKEDYERKLNE-------LRRQL 686

  Fly   548 NDCKSDHNQDLRELE---MAQNELVKELKRQLLIIDNFVPIEVKQRLYTQAKYDEEQEEWKFSSM 609
            |..::.:.:.|| |:   .||:..:|.|:.:|..:.     :||.||  ..|..||....|
Mosquito   687 NHFQATNKEHLR-LQRNMQAQDAKIKTLRGELAELK-----QVKTRL--MKKIQEESNRHK---- 739

  Fly   610 SLPTPPGGDGKFSSKRPVSHPQRRRPTSEY-----ALQEAKSNSPSSLRFKSENIVNYELEMPCR 669
                      :..|::.....|.|:.|.::     :||...:.....|:.|:|.:.|..
Mosquito   740 ----------EMESRKTREIAQLRKETRKHKNMIKSLQAQGAAKDQVLKRKTEEVFNLR------ 788

  Fly   670 TTQEYRTPKVSASLQAVLAQAMQTGGDDIDIVDSHTNSLRSRLENI 715
                    |....:.::.|.....|...|..:...|...:||.|.:
Mosquito   789 --------KSQRGIMSLKAAGRVQGNTSIGSMLQGTKRFKSRWEEL 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	149/376 (40%)
		Smc	<431..>580	CDD:440809	48/258 (19%)
Klp31E	XP_061516566.1	None