Protein Alignment Klp68D and sub

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_308782.4
• Gene: sub / 1270110
• VectorBaseID: AGAMI1_012903
• Length: 632
• Species: Anopheles gambiae
• Alignment Length: 611
• Identity: 154/611 - (25%)
• Similarity: 244/611 - (39%)
• Gaps: 144/611 - (23%)

  Fly     9 GTGSSQTPNECVQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDGNKEQRKVFTYDAAY 73
            |........|.|:|.:|.||.:............||...|...|.|:..     .:|.:|:...:
Mosquito    69 GANLESREEETVKVCLRLRPCTKTGGRMAFKIKDNVLIARCPGESQSTA-----SQKHYTFSNVF 128

  Fly    74 DASATQTTLYHEVVFPLVSSVLEGFNGCIF-AYGQTGTGKTFTMEGVRGNDELMGIIPRTFEQIW 137
            :.:.:|..:|...:.|.:...| |..|..| .||.:|:|||:|:   .||:...||:||:.|||:
Mosquito   129 EENVSQAEVYDCCIRPTIRPTL-GEPGATFLTYGTSGSGKTYTL---LGNETNPGIVPRSIEQIY 189

  Fly   138 LHI--------------------------------------------NRT-------ENFQF--- 148
            ..:                                            :||       :..||
Mosquito   190 EELYDNISTEPSLKMECMKPIPLSDESVLDELRKLRLIKSRLQGGEESRTVISDTIQQQHQFEPL 254

  Fly   149 -------LVDVSYLEIYMEELRDLLKPNS-----KHLEVRERGSGVYVPNLHAINCKSVEDMIKV 201
                   .:.:|::|||.|.:.|||....     |.::|.......|:..|..:...:.||...:
Mosquito   255 DMGDKRVFIWISFVEIYNENVYDLLNVEGDYGKRKAMKVLSNDGNAYIKGLSTLYAGTKEDAYAL 319

  Fly   202 MQVGNKNRTVGFTNMNEHSSRSHAIFMIKIEMCDTETNTIKVGKLNLIDLAGSERQSKTGASAER 266
            :|.|.::.|.|.|::|.:|||||:||.:.:......|..|........|||||||..|||...:|
Mosquito   320 LQYGLQSATYGATDVNSNSSRSHSIFTVTVITHSMATQRISQSVYKFCDLAGSERLKKTGTVGDR 384

  Fly   267 LKEASKINLALSSLGNVISALAESSP----H--VPYRDSKLTRLLQDSLGGNSKTIMIANIGPSN 325
            ||||.|||.:|..||..:..:.::..    |  ||.||||||.::|.:|.|.....||.|:.|:.
Mosquito   385 LKEAQKINTSLLVLGRCLETVHKNQKTKKLHELVPVRDSKLTMIIQSALLGKEPMTMIVNVYPTE 449

  Fly   326 YNYNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKRLIGPQQQQRSEKQVTAKKQ 390
            ..|:|.|..|.::|.||.|    :.::.|:..|                   ...|.:......|
Mosquito   450 EFYDENLNVLNFSSIAKQI----VISKHPKIMK-------------------APHSTRYSFFLSQ 491

  Fly   391 RVKKPKKETVTKEMSDSLQVSTIEQPVEDDSDPEGAESESDK-ENEAEVAKSNEELERERVENSK 454
            .:..|..:..|..:.                    .|.||.| ||:..||    |.|::..|...
Mosquito   492 AISSPSAKVDTHRLL--------------------MEYESLKLENDRLVA----EAEQKSAEIVC 532

  Fly   455 LAAKLAELEGQLVRGGKNLLDTYS----------ERQIELEKKLVEIAERKKREIEIQQQLELQE 509
            |..|||..|.||   ...|.|.:.          |.:|...|:|| :...|.:...::.:|:.:|
Mosquito   533 LQKKLAIQEFQL---RNELTDNFQQHFAKMEESYETRIRSAKELV-VLPYKHQLASLENKLKSKE 593

  Fly   510 ETTLEIRERNVSLEQEVELKKRKLSK 535
            :..:|:.:.....|::::..:.:|||
Mosquito   594 QIIMEMEDEQDDYEKKLKAYEEELSK 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	113/403 (28%)
		Smc	<431..>580	CDD:440809	30/116 (26%)
sub	XP_308782.4	Motor_domain	80..466	CDD:473979	110/394 (28%)
		SMC_N	<509..>623	CDD:481474	32/119 (27%)