Protein Alignment Klp68D and Klp61F

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_061499619.1
• Gene: Klp61F / 1269725
• VectorBaseID: AGAMI1_012015
• Length: 1101
• Species: Anopheles gambiae
• Alignment Length: 862
• Identity: 249/862 - (28%)
• Similarity: 401/862 - (46%)
• Gaps: 180/862 - (20%)

  Fly     5 SRRPGTGSSQTP--NECVQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDGNKEQRKVF 67
            |.|..:.::..|  |:.|||.||.||.:.||:..||.|||.|...|.:....|..|....  |.|
Mosquito     8 SERNQSNNAYRPKSNQNVQVYVRVRPTNAREKLIRSQEVVEVVSTRELQLKSNYTDSRTS--KKF 70

  Fly    68 TYDAAYDASATQTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVR--------GNDE 124
            |:|..:..::.|..:|..||.|.:..||.|||..:|||||||||||.||.|..        .:|.
Mosquito    71 TFDRTFAPNSKQHEVYQAVVAPYIEEVLSGFNCTVFAYGQTGTGKTHTMVGEEEQNLSAAWEDDT 135

  Fly   125 LMGIIPRTFEQIWLHINRTENFQFLVDVSYLEIYMEELRDLLKPNSK-----HLEVRERGSGVYV 184
            ..|||||....::..:..|| .:|.:.:||||:|.|||.|||..:..     ..:|:::|| |.|
Mosquito   136 QTGIIPRAVNHLFDELRMTE-LEFSMRISYLELYNEELCDLLSTDDTIKIRIFDDVQKKGS-VIV 198

  Fly   185 PNLHAINCKSVEDMIKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIKIEM----CDTETNTIKVGK 245
            ..|..|...|.:|:.|::..|.:.|....|.||..|||||.||.|.:.:    .|.| ..:|:||
Mosquito   199 QGLEEIPVHSKDDVYKLLAKGQERRKTASTLMNAQSSRSHTIFSIIVHIKENGIDGE-EMLKIGK 262

  Fly   246 LNLIDLAGSERQSKTG-ASAERLKEASKINLALSSLGNVISALAESSPHVPYRDSKLTRLLQDSL 309
            |||:||||||..||.| ....|.:|...||.:|.:||.||:||.|.:||:|||:||||||||:||
Mosquito   263 LNLVDLAGSENISKAGNEKGIRTRETVNINQSLLTLGRVITALVEKTPHIPYRESKLTRLLQESL 327

  Fly   310 GGNSKTIMIANIGPSNYNYNETLTTLRYASRAKSIQNQPIKNED-PQDAKLKEYQEEIERLKRLI 373
            ||.:||.:||.:.|.|.::.|||:||.||.|||:|||:|..|:. .:...:|||.|||:||||.:
Mosquito   328 GGRTKTSIIATVSPGNKDFEETLSTLEYAHRAKNIQNKPEANQKLSKKTVIKEYTEEIDRLKRDL 392

  Fly   374 GPQQQQRSEKQVTAKKQRVKKP--KKETVTKEMSDSLQVSTIEQPVEDDSDPEGAESE---SDKE 433
               ...|.:..:...::...:.  |.|..|||::|.|  :.|:...||.:..|...:|   |..|
Mosquito   393 ---MAARDKNGIYLAEETYNEMVYKSEAATKELNDKL--ALIKALKEDLARKEAIFNEVACSLAE 452

  Fly   434 NEAEVAKSNEELERERVE--NSKLAAKLAELEGQLVRGGKNLLDT---YSERQIELE-------- 485
            .|.::.::.::|.:.|.|  |:|                |||..|   |.|:::.||
Mosquito   453 REEQLRRTADDLGQTRAELSNTK----------------KNLSKTKRRYVEKKVILEHHLKTEQM 501

  Fly   486 -----KKLVEIAER-------------KKREIEIQQQLELQEETTLEIRERNVSLEQEVELKKRK 532
                 |:|:.:.|.             ::||::.:.: ...|:....:|.|..:::.:|   .:.
Mosquito   502 LTGQAKELINVVESVTEDTNGLHDTVDRRRELDSRNK-SATEQFVDRVRHRIGTIQDDV---SKM 562

  Fly   533 LSKC------------------YAKYLALQQELNDCKSDHNQDLRE---------------LEMA 564
            ..:|                  .|.|:..:..|:..::..:..|::               .|..
Mosquito   563 ADECNRLTVDMNVGWESYNKQQEAAYIETKAHLSTLETVSHSLLQQNASLVGAFKASMEGKTEAR 627

  Fly   565 QNELVKEL----KRQLLIIDNFVPIEVKQRLYTQAKYDEEQEEWKFSSMSLPTPPGGDGKFSSKR 625
            ::|:::.|    :.:|.:::.|.....|.:|..:...|.:.|:.:             .:|  :|
Mosquito   628 RDEVIQFLDQVEQSRLALMETFTSTMEKLKLGIRTTIDAQHEQVQ-------------AQF--ER 677

  Fly   626 PVSHPQRRRP-----TSEYALQEAKSNSPSSLRFKSENIV-NYELEMPCRTTQEYR-TPKVSASL 683
            .::|.|.|..     ...:..|.|:.:|.:|...::..:: :|..:...:...|.: |.:..|.:
Mosquito   678 MIAHGQARESKCAEFCQTFTGQLAELDSITSTFERNHTVLQDYVAQSEQKKQNELKATKEFEAKV 742

  Fly   684 QAVLAQAMQTGGDDIDIVDSHTNSLRSRLENIINANANGGAGPGAGVAVGSSIPNV------RNI 742
            .::||          |.|...|.|.:.:.|                  :.|.:.:|      :..
Mosquito   743 SSLLA----------DFVQQMTASSQQQTE------------------LSSVVVHVSDELVSQGT 779

  Fly   743 KSSRGLPSAASNLDSNR 759
            |:::.|.:..|::|..|
Mosquito   780 KATKQLQTIRSSIDEKR 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	155/348 (45%)
		Smc	<431..>580	CDD:440809	33/216 (15%)
Klp61F	XP_061499619.1	None