Protein Alignment Klp68D and kif27

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_031750817.1
• Gene: kif27 / 100497455
• XenbaseID: XB-GENE-6039606
• Length: 1393
• Species: Xenopus tropicalis
• Alignment Length: 793
• Identity: 246/793 - (31%)
• Similarity: 377/793 - (47%)
• Gaps: 143/793 - (18%)

  Fly    14 QTPNECVQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDGNKEQRKVFTYDAAYDASAT 78
            :||   |:|.:|.||:.:||........|.:.||     .|.|:.|   :.:|||:|..:..|::
 Frog    15 ETP---VKVALRVRPLLSREILHNHQVCVRLVPN-----TQQVIVG---KDRVFTFDFVFGKSSS 68

  Fly    79 QTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGN-----DELMGIIPRTFEQIWL 138
            |..:|...:.||:.|::||:|..:|||||||:|||:|:.|  ||     ||..|||||..::::.
 Frog    69 QDDVYRSSIKPLLGSLMEGYNATVFAYGQTGSGKTYTIGG--GNVASVADEEKGIIPRAIQELFQ 131

  Fly   139 HINRTENFQFLVDVSYLEIYMEELRDL--LKPNSKHLEVR--ERGSGVYVPNLHAINC--KSVED 197
            .|....|.:|.|.|||:|:|.|||.||  |:.|.|.|.:|  |:|:.|.|   .|..|  ::.::
 Frog   132 CIAERHNVEFSVRVSYIEVYKEELLDLLELETNMKDLHIREDEKGNTVIV---GAKECQVENADE 193

  Fly   198 MIKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIKIEMC--------DTETNTIK--VGKLNLIDLA 252
            ::.::..|:..|..|.|.|||.||||||||.|.|  |        |..||:|:  ..|.:.:|||
 Frog   194 VMSLLAAGSAARHTGSTQMNERSSRSHAIFTITI--CQQSSQHGDDAGTNSIQTITSKFHFVDLA 256

  Fly   253 GSERQSKTGASAERLKEASKINLALSSLGNVISALAE---SSPHVPYRDSKLTRLLQDSLGGNSK 314
            ||||.:|||.:.||.||:.:||..|.:||||||||.:   .|.|:||||:|:||:|:||||||:|
 Frog   257 GSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPKRKSAHIPYRDAKITRILKDSLGGNAK 321

  Fly   315 TIMIANIGPSNYNYNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKRLIGPQQQQ 379
            |:||..|.||:.:.:|:|.:|:||:||::|:|:|:.|.:|...::.|.:.||:.|:..:..||..
 Frog   322 TVMITCISPSSSDLDESLNSLKYANRARNIKNKPVVNYNPDWDRMDEMELEIKVLREALQNQQSS 386

  Fly   380 RSEKQVTAKKQRVKKPKKETVTKEMSDSLQVSTIEQPVEDDSDPEGAESESDKENEAEVAKSNEE 444
            |                             ||...|..:|.|..:    :..:..|.:||:...|
 Frog   387 R-----------------------------VSRTSQVSQDWSQGK----DKIRSLEEKVAQLQLE 418

  Fly   445 LERER---VENSKLAAKLAELEGQLVRGGKNLLDTYSERQIELEKKLVEIAERKKREIEIQQQLE 506
            ...:|   .|...|...|.::.| |.:..||.:..:......|...:...||...|| |......
 Frog   419 CFNQRHCTEEAFSLFLDLKDISG-LPQSEKNRVQDWLHLAEGLRSPVAADAEGSSRE-EPHHVTI 481

  Fly   507 LQEETTLEIRERNVSLEQEV-ELKKRKLSKCYAKYLALQQELNDCKSDHNQDLRELEMAQNELVK 570
            ||.:..|:..:..::.::|| ..||.:|.....:..:||||    ..::.:.|:|.|..:....:
 Frog   482 LQLKRELKKCQDALATDEEVFARKKLELKGLQEQIQSLQQE----TEEYQKCLQEAEYTKTLQTE 542

  Fly   571 ELKRQLLIIDNFVPIEVKQ------RLYTQAKYDEEQEEWKFSSMSLPTPPGGDGKFSSKRPVSH 629
            :|..|.|:||     |:|.      |.::|...|||:...:.|......||.           :|
 Frog   543 KLVEQQLLID-----ELKSKKPEIYRQFSQENEDEEELPREISQRPHTVPPS-----------TH 591

  Fly   630 PQRRRPTSEYALQEAKSNSPSSLRFKSENIVNYELEMPCRTTQEYRTP-----KVSASLQAVLAQ 689
            .|:   .|..:||.|....|..:|....   :|.||   |....:||.     ::......||.:
 Frog   592 TQK---LSSSSLQAAGQAEPRKVRTSPP---SYSLE---RMVAGFRTRSQMLLELIEEQDEVLHE 647

  Fly   690 AMQTGGDDIDIVDSHTNSLRSRLENIINA----------------------NANGGAGPGAGVAV 732
            ......::........|..:|.....||.                      :||..|.|......
 Frog   648 KFSDQSEEEPDEPEKENRKKSPFRRSINRTWTRRQGSAGAETLNSNSDRENDANSNACPALESLR 712

  Fly   733 GSSIPNVRNIKSS 745
            .|.:.||..:|:|
 Frog   713 ESQVLNVEKLKTS 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	153/354 (43%)
		Smc	<431..>580	CDD:440809	36/152 (24%)
kif27	XP_031750817.1	KISc_KIF4	16..352	CDD:276823	152/353 (43%)
		SMC_prok_B	<363..>586	CDD:274008	58/266 (22%)
		SMC_prok_B	<481..900	CDD:274008	59/274 (22%)
		Smc	<707..>1237	CDD:440809	5/19 (26%)