Protein Alignment Klp68D and kif3c

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_002942156.1
• Gene: kif3c / 100491018
• XenbaseID: XB-GENE-959437
• Length: 753
• Species: Xenopus tropicalis
• Alignment Length: 794
• Identity: 328/794 - (41%)
• Similarity: 475/794 - (59%)
• Gaps: 92/794 - (11%)

  Fly    12 SSQTPNECVQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDGNKEQRKVFTYDAAYDAS 76
            |....:|.::|||||||.:.:|.:.....:|::....|.|.:::......|..|.||:||.||||
 Frog     3 SKAKSSEALKVVVRCRPTNRKEEAAGYEGIVDMDIKLGQVTMRHPRANPGELAKTFTFDAVYDAS 67

  Fly    77 ATQTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELMGIIPRTFEQIWLHIN 141
            :.|..||.|.|.||:.|||:||||.||||||||||||:||:||....|..|:||.||:.|:.||:
 Frog    68 SKQADLYDETVRPLIDSVLQGFNGTIFAYGQTGTGKTYTMQGVWAEPEKRGVIPNTFDHIFTHIS 132

  Fly   142 RTENFQFLVDVSYLEIYMEELRDLL-KPNSKHLEVRER-GSGVYVPNLHAINCKSVEDMIKVMQV 204
            |::|.|:||..||||||.||:|||| |..::.||::|. .:|||:.:|.:...|:|:::..||.:
 Frog   133 RSQNQQYLVRASYLEIYQEEIRDLLCKDQNRKLELKENPETGVYIKDLSSFVTKNVKEIEHVMNL 197

  Fly   205 GNKNRTVGFTNMNEHSSRSHAIFMIKIEMC-----DTETNTIKVGKLNLIDLAGSERQSKTGASA 264
            ||::|:|..|.|||:|||||.||:|.:| |     |.|.: |:||||||:||||||||||||.:.
 Frog   198 GNQSRSVACTYMNEYSSRSHTIFVITVE-CSEIGVDGEEH-IRVGKLNLVDLAGSERQSKTGING 260

  Fly   265 ERLKEASKINLALSSLGNVISALAES-SPHVPYRDSKLTRLLQDSLGGNSKTIMIANIGPSNYNY 328
            :|.||||||||:||:||||||||.:. |.|:||||||||||||||||||:||||:|.:||::.||
 Frog   261 DRPKEASKINLSLSALGNVISALVDGRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASVNY 325

  Fly   329 NETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKRLIGPQQQQRSEKQVTAKKQRVK 393
            :|||:|||:|:|||:|:|:|..||||:|..|:|:||||.|||       .|..::.:.:||:|..
 Frog   326 DETLSTLRFANRAKNIKNKPRINEDPKDTLLREFQEEIARLK-------AQLEKRGMLSKKRRRN 383

  Fly   394 KPKKETV----------TKEMSDSL-----------QVSTIEQPVEDDSDPEGAESESDKENEAE 437
            ..:|::|          .::..|.|           |...|||......|.....:|...:...|
 Frog   384 SRRKKSVDGDGTPDTEAEEDNEDKLIEKNVGSYLKEQAERIEQEKAAIQDDHSLLAEEKLKLIEE 448

  Fly   438 VAKSNEELERERVENSKLAAKLAELEGQLVRGGKNLLDTYSERQIELEKKLVEIAERKKREIEIQ 502
            ..|..::|.:|:.....||.|...:|.:|:.||||::|..:|:|..||.|..||||:|:||.||.
 Frog   449 KEKMMDDLTKEQKATELLAVKFKAMESKLLVGGKNIMDHTNEQQKMLEIKRQEIAEQKRREREIL 513

  Fly   503 QQLELQEETTLEIRERNVSLEQEVELKKRKLSKCYAKYLALQQELNDCKSDHNQDLRELEMAQNE 567
            ||:.|::|.|:::|....||:||||:|.:||.|.|||..|::.|:.|...::.:..::||.||||
 Frog   514 QQMLLRDEATVDLRGTYTSLQQEVEMKTKKLKKLYAKLQAVKGEIQDQHDEYVRVRQDLEQAQNE 578

  Fly   568 LVKELKRQLLIIDNFVPIEVKQRLYTQAKYDEEQEEWKFSSMSLPTPPG---GDGKFSSKRPVSH 629
            ..:|||.:.|||:||:|.|.|.::..:..||.|:::|||..:   .|||   |......:||.|.
 Frog   579 QTRELKFKYLIIENFIPPEEKNKIMNRLYYDSEEDQWKFQPL---VPPGNASGGNDTMKRRPSSA 640

  Fly   630 PQRRRPTSEYA-LQEAKSNSPSSLRFKSENIVNYELEMPCRTTQEYRTPKVSASLQAVLAQAMQT 693
            ...:||.|:|| :.......|   |:::|||:..||::         ||      .|:.......
 Frog   641 VGYKRPISQYARVAMVMGYHP---RYRAENIMFLELDL---------TP------PALFEMDFSK 687

  Fly   694 GGDDIDIVDSHTNSLRSRLENIINANANGGAGPGAGVAVGSSIPNVRNIKSSRG-------LPSA 751
            ...:.|....|...| :||::::..                  |....::.||.       |||:
 Frog   688 DRSEQDPRALHLERL-TRLDSLMER------------------PAAARVRKSRSWCQQPKLLPSS 733

  Fly   752 ASNL---DSNRRPP 762
            .:::   .|::|.|
 Frog   734 TTHISLTSSSQRCP 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	189/338 (56%)
		Smc	<431..>580	CDD:440809	61/148 (41%)
kif3c	XP_002942156.1	KISc_KIF3	9..341	CDD:276822	187/333 (56%)
		SMC_N	<340..618	CDD:481474	103/284 (36%)