Protein Alignment Klp68D and kif3a

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_017947685.1
• Gene: kif3a / 100145686
• XenbaseID: XB-GENE-986464
• Length: 766
• Species: Xenopus tropicalis
• Alignment Length: 722
• Identity: 292/722 - (40%)
• Similarity: 438/722 - (60%)
• Gaps: 62/722 - (8%)

  Fly     9 GTGSSQTPNEC--VQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDGNKEQRKVFTYDA 71
            |...:..|..|  |:|||||||::.|||:..|...|.|...||.:.:.. ||...|..|.||:|.
 Frog    69 GINRADKPESCDNVKVVVRCRPLNERERAMNSKMAVGVDEMRGTITVHK-VDSMNEPPKTFTFDT 132

  Fly    72 AYDASATQTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELMGIIPRTFEQI 136
            .:...:.|..:|:....|::.|||||:||.|||||||||||||||||||...||.||||.:|..:
 Frog   133 VFGPDSNQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAVPELRGIIPNSFAHV 197

  Fly   137 WLHINRTE-NFQFLVDVSYLEIYMEELRDLL-KPNSKHLEVRERGS-GVYVPNLHAINCKSVEDM 198
            :.||.:.| :.:|||.|||||||.||:|||| |..|:.|||:||.. |||:.:|......:.:||
 Frog   198 FGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQSQRLEVKERPDVGVYIKDLSGYVVNNADDM 262

  Fly   199 IKVMQVGNKNRTVGFTNMNEHSSRSHAIFMIKIEMCDTETN---TIKVGKLNLIDLAGSERQSKT 260
            .::|.:|:|||:||.||||||||||||||.|.||..:...:   .:::|||:|:||||||||:||
 Frog   263 DRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGADGNIHVRMGKLHLVDLAGSERQAKT 327

  Fly   261 GASAERLKEASKINLALSSLGNVISALAE-SSPHVPYRDSKLTRLLQDSLGGNSKTIMIANIGPS 324
            ||:.:|||||:||||:||:||||||||.: .|.|||||:|||||||||||||||||:|.|||||:
 Frog   328 GATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPA 392

  Fly   325 NYNYNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKRLI------------GPQQ 377
            :|||:||::|||||:|||:|:|:...||||:||.|:::|:|||.||:.:            |.:.
 Frog   393 DYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEDLKKKLEEGEDVSGSDDSGTED 457

  Fly   378 QQRSEKQV--TAKKQRVKKPKKETVTKEMSDSLQVSTIEQPVEDDSDPEGAESESDKENE----- 435
            ....:.::  ..:|::.::.||:....:|:        |.....|.:.:..|::.|.|.|
 Frog   458 DDDEDGEIGEDGEKKKKRRGKKKGSPDKMA--------EMQARIDEERKALEAKLDMEEEERNKA 514

  Fly   436 -AEVAKSNEELERERVENSKLAAKLAELEGQLVRGGKNLLDTYSERQIELEKKLVEIAERKKREI 499
             ||:.:..::|.:.:.|:..|..||:.||.:::.||.:||....|::..||:...|:.||:||..
 Frog   515 RAELERREKDLFKAQQEHHSLLEKLSALEKKVIVGGVDLLAKAEEQERLLEESNFELEERRKRAE 579

  Fly   500 EIQQQLELQEETTLEIRERNVSLEQEVELKKRKLSKCYAKYLALQQELNDCKSDHNQDLRELEMA 564
            :::::||.:|:..|:|.|:..||::|.:.|.:||.|.:...:|.:.|:.|.:.:|.:::..|...
 Frog   580 KLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLEN 644

  Fly   565 QNELVKELKRQLLIIDNFVPIEVKQRLYTQAKYDEEQEEWKFSSMSLPTPPGGDGKFSSKRPVSH 629
            ..:|.:||:.|:.|||:|:|.|.::.:.....::|:..||:...::..     ......:.||..
 Frog   645 IRQLSRELRLQMNIIDSFIPQEYQEMIENYVHWNEDIGEWQLKCVAYT-----GNNMRKQTPVPD 704

  Fly   630 PQRRRP----TSEYALQEAKSNSPSSLRFKSENIVNYELEMPCRTTQEYRTPKV-----SASLQA 685
            .:.:.|    .|...|...:.:...||         .:||.| ||::....||.     ||..:|
 Frog   705 KKEKDPFEVDLSHVYLAYTEESLRQSL---------MKLERP-RTSKGKTRPKTGRRKRSAKPEA 759

  Fly   686 VLAQAMQ 692
            |:...:|
 Frog   760 VINSLLQ 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	194/337 (58%)
		Smc	<431..>580	CDD:440809	47/154 (31%)
kif3a	XP_017947685.1	KISc_KIF3	80..412	CDD:276822	192/332 (58%)
		Smc	<485..>655	CDD:440809	49/177 (28%)