Protein Alignment Klp68D and kif3b

DIOPT Version :10

• Sequence 1: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001093615.1
• Gene: kif3b / 100101641
• ZFINID: ZDB-GENE-050119-3
• Length: 775
• Species: Danio rerio
• Alignment Length: 832
• Identity: 366/832 - (43%)
• Similarity: 506/832 - (60%)
• Gaps: 117/832 - (14%)

  Fly    12 SSQTPNECVQVVVRCRPMSNRERSERSPEVVNVYPNRGVVELQNVVDGNK-EQRKVFTYDAAYDA 75
            |....:|.|:||||||||:.:||......||:|....|.|.:.|....:. |..||||:|:.||.
Zfish     2 SKSKSSESVKVVVRCRPMNEKERVANFNRVVSVDVKLGQVAVCNPRGASSHEHPKVFTFDSVYDW 66

  Fly    76 SATQTTLYHEVVFPLVSSVLEGFNGCIFAYGQTGTGKTFTMEGVRGNDELMGIIPRTFEQIWLHI 140
            ::.|..||.|...|||.|||.||||.||||||||||||:||||||.:.|..|:||.:||.|:.||
Zfish    67 NSKQMELYDETFRPLVDSVLFGFNGTIFAYGQTGTGKTYTMEGVRNDPERRGVIPNSFEHIFTHI 131

  Fly   141 NRTENFQFLVDVSYLEIYMEELRDLL-KPNSKHLEVRER-GSGVYVPNLHAINCKSVEDMIKVMQ 203
            :.::|.|:||..||||||.||:|||| |..::.||::|| .:||||.:|.:...|||.::..||.
Zfish   132 SCSQNQQYLVRASYLEIYQEEIRDLLSKDQARRLELKERPDTGVYVKDLSSFVTKSVREIEHVMN 196

  Fly   204 VGNKNRTVGFTNMNEHSSRSHAIFMIKIEMC-----DTETNTIKVGKLNLIDLAGSERQSKTGAS 263
            |||:||:||.||||||||||||||:|.|| |     |.| |.|:||||||:||||||||:||||.
Zfish   197 VGNQNRSVGATNMNEHSSRSHAIFVITIE-CSELGPDGE-NHIRVGKLNLVDLAGSERQTKTGAQ 259

  Fly   264 AERLKEASKINLALSSLGNVISALAES-SPHVPYRDSKLTRLLQDSLGGNSKTIMIANIGPSNYN 327
            .||||||:||||:||:||||||||.:. |.|:||||||||||||||||||::|:|:|||||::||
Zfish   260 GERLKEATKINLSLSALGNVISALVDGRSTHIPYRDSKLTRLLQDSLGGNARTVMVANIGPASYN 324

  Fly   328 YNETLTTLRYASRAKSIQNQPIKNEDPQDAKLKEYQEEIERLKRLIGPQQQQRSEKQVTAKKQRV 392
            ..|||||||||:|||:|:|:|..||||:||.|:|:||||.|||        ::.||:...|::|.
Zfish   325 VEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLK--------EQLEKRSGRKRRRR 381

  Fly   393 KKPKKETVTKEMSDSLQVSTIEQPVEDDSDPEGAES--ESDK----------------------- 432
            ::.:.....:|..|.      |...:||.|.|..|.  ::||
Zfish   382 RRRRVGEGGEEFEDG------EDEEDDDDDDEDEEEGVDADKNIADYWHEQQEKLEKERRAIMED 440

  Fly   433 -----ENEAEVAKSNE----ELERERVENSKLAAKLAELEGQLVRGGKNLLDTYSERQIELEKKL 488
                 |.:..:.|..|    :|.:|:..:..|.||:..:|.:|:.||||::|..:|:|..||.|.
Zfish   441 HSLVAEEKQRLLKEKERKMTDLHKEKEASEMLTAKVKAMESKLLVGGKNIVDHTNEQQKVLELKR 505

  Fly   489 VEIAERKKREIEIQQQLELQEETTLEIRERNVSLEQEVELKKRKLSKCYAKYLALQQELNDCKSD 553
            .||||:|:||.|::|::|.::|.|||::|...||:|||::|.:||.|.::|..:::.|:.|.:.:
Zfish   506 QEIAEQKRREREMKQEMECRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQSVKSEIQDAQDE 570

  Fly   554 HNQDLRELEMAQNELVKELKRQLLIIDNFVPIEVKQRLYTQAKYDEEQEEWKFSSMSLPTPPGGD 618
            |.:..:|||..||||.:|||.:.|||:||:|:|.|.::.|:|.:|||.:.||.:.:   |.....
Zfish   571 HVKYRQELEQTQNELTRELKLKHLIIENFIPMEEKNKIVTRATFDEEDDLWKMTPI---TRIQNS 632

  Fly   619 GKFSSKRPVSHPQRRRPTSEYALQEAKSNSPSSLRFKSENIVNYELEMPCRTTQEYRTPKVSASL 683
            .....|||||....|||.|::| :.|....| .:|:|:|||:..||::|.|||::|..|.::..:
Zfish   633 DHQMMKRPVSAVGYRRPLSQHA-RMAMLMRP-DVRYKAENILLLELDLPSRTTKDYEGPVIAPKV 695

  Fly   684 QAVLAQAMQTGGDDIDIVDSHTNSLRSRLENIINANANG-----GAGPGAGVAVGSSIPNVRNIK 743
            .|.|..|:                   |.|:.|..:|:|     |:.||...
Zfish   696 AAALEDAL-------------------REEDEIQVDASGFHASLGSSPGLSA------------- 728

  Fly   744 SSRGLPSAASNLDSNRRPPTGRLPAKKPASA-----------YPKARGLVNK 784
            |:.|.    |....:.||.||: ....|.||           ||::||||.|
Zfish   729 SAAGF----SKKPKSGRPKTGK-KVSTPTSAHSPLSGSGSPLYPQSRGLVPK 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	208/339 (61%)
		Smc	<431..>580	CDD:440809	62/180 (34%)
kif3b	NP_001093615.1	KISc_KIF3	15..341	CDD:276822	201/327 (61%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	372..419		13/52 (25%)
		Mplasa_alph_rch	<425..>611	CDD:275316	66/185 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	716..775		19/76 (25%)