Protein Alignment CG10907 and PPIG

DIOPT Version :10

• Sequence 1: NP_648508.1
• Gene: CG10907 / 39331
• FlyBaseID: FBgn0036207
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_004783.2
• Gene: PPIG / 9360
• HGNCID: 14650
• Length: 754
• Species: Homo sapiens
• Alignment Length: 593
• Identity: 140/593 - (23%)
• Similarity: 238/593 - (40%)
• Gaps: 151/593 - (25%)

  Fly     4 IYIQEPPTSGKVLLKT-TVGDIDIELWARECPKACRNFVQLCL--EG---------YYKNTEFHR 56
            |.:|.|.....:.:.. ..|.:..||::..|||.|.||..||.  :|         :||:..|||
Human     3 IKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHR 67

  Fly    57 LVKGFIVQGGD-PNGDGTGGESIYGQPFKDEFHSRLRYTRRGLVGMANSGKDDNGSQFFFTFAPT 120
            :||.|:||||| ..|:|.|||||||..|:||..: :::.:..|:.|||.|||.||||||.|..||
Human    68 VVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFA-VKHNKEFLLSMANRGKDTNGSQFFITTKPT 131

  Fly   121 PELQNKNTLFGK-ITGDTIYNMLKLEDGIVDHQERPMHAHRIVSTEVLSNPFDDIVPRILS---- 180
            |.|...:.:||: |:|..:...       :::|:          |:..|.||.::  ||||
Human   132 PHLDGHHVVFGQVISGQEVVRE-------IENQK----------TDAASKPFAEV--RILSCGEL 177

  Fly   181 QPSTKSKKTKKERQGVKNFGLLSFGE-------EAEGDEEETNVYVKQNAGKAKSLH-------- 230
            .|.:|.||.:|:|....:....|..:       ::..|..::....::.:.|.|..|
Human   178 IPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHK 242

  Fly   231 --------------------DVTDDPKLSKEPIRVPKV-----------------EKADIEEHLS 258
                                ::...|:.:..|..:|.:                 |:.:.|....
Human   243 KEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERE 307

  Fly   259 DDC-PEDSVKDKPSTASSDLIKMKLSKRSKSGADKKVQPVEEKSDSED----DEDVLLTREEEQ- 317
            .:| |.:|   :|::....|:..:..::.|....::.: ...:|.|.|    .|.....|:|.|
Human   308 RECNPPNS---QPASYQRRLLVTRSGRKIKGRGPRRYR-TPSRSRSRDRFRRSETPPHWRQEMQR 368

  Fly   318 ---------SRKVSEEKSKIREEIASLKKQYQMDKQSKDKLVNG-----------QEKAAKSNEI 362
                     .|.:..:||::.|    :|:..:...:.|::.:..           .||..|..:.
Human   369 AQRMRVSSGERWIKGDKSELNE----IKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDH 429

  Fly   363 KGSSENHYINDFIESKEKYTAKVKLQPKGQSREAFTLSLLSKFRTKLDNLKQKSSSDDGESEPKD 427
            |.:|:...|....|..:||..|||.:.|.:||               ...|:||.|.:.:|:...
Human   430 KSNSKERDIRRNSEKDDKYKNKVKKRAKSKSR---------------SKSKEKSKSKERDSKHNR 479

  Fly   428 IDDRVVEQEIIGDDWLSHTLNFNSTTPVLAKDANKKGDDWYDAYDPRNPLNKRKRGETGSSKSSS 492
            .:::.:.....|.|        :.......|.::.||.|    .:......|.|:.|:.|::...
Human   480 NEEKRMRSRSKGRD--------HENVKEKEKQSDSKGKD----QERSRSKEKSKQLESKSNEHDH 532

  Fly   493 GKSKSSKR 500
            .|||...|
Human   533 SKSKEKDR 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10907	NP_648508.1	cyclophilin_CeCYP16-like	8..178	CDD:238906	65/183 (36%)
		PTZ00121	<279..>426	CDD:173412	34/171 (20%)
		CWC27_CTD	390..451	CDD:412084	10/60 (17%)
PPIG	NP_004783.2	cyclophilin	8..175	CDD:469651	69/186 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	182..754		68/394 (17%)
		PTZ00121	<392..752	CDD:173412	36/176 (20%)