DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10907 and AT4G33060

DIOPT Version :9

Sequence 1:	NP_648508.1	Gene:	CG10907 / 39331	FlyBaseID:	FBgn0036207	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_195032.2	Gene:	AT4G33060 / 829443	AraportID:	AT4G33060	Length:	504	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	213/548 - (38%)
Similarity:	292/548 - (53%)	Gaps:	100/548 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSNIYIQEPPTSGKVLLKTTVGDIDIELWARECPKACRNFVQLCLEGYYKNTEFHRLVKGFIVQG 65
            ||.:|:.||||.|||::.||.|.||:|||.:|.||:.|||||||||||:.||.|||::.||:|||
plant     1 MSTVYVLEPPTKGKVIVNTTHGPIDVELWPKEAPKSVRNFVQLCLEGYFDNTIFHRVIPGFLVQG 65

  Fly    66 GDPNGDGTGGESIYGQPFKDEFHSRLRYTRRGLVGMAN-SGKDDNGSQFFFTFAPTPELQNKNTL 129
            |||.|.||||:||||..|.||||||||::.||:|.||| |..:.||||||||......|..|:|:
plant    66 GDPTGSGTGGDSIYGGVFADEFHSRLRFSHRGIVAMANASSPNSNGSQFFFTLDKCDWLDKKHTI 130

  Fly   130 FGKITGDTIYNMLKLEDGIVDHQERPMH-AHRIVSTEVLSNPFDDIVPRILSQPSTKSKKTKKE- 192
            |||:|||:|||:|:|.:......:||:. |.:|:|.|||.|||:|||||:|::.|.:|....||
plant   131 FGKVTGDSIYNLLRLGEVDTSKDDRPLDPAPKILSVEVLWNPFEDIVPRVLAKTSEESAAEIKEP 195

  Fly   193 -RQGVKNFGLLSFGEEAEGDEEETNVYVKQNAGKAKSLHDVTDDPKLSKEPIRVPKVEKADIEEH 256
             .:.||...|||||||||.:|:|..| |||   |.||.|||.:||:|.       |.|.:|.|.:
plant   196 PTKPVKKLNLLSFGEEAEEEEKELAV-VKQ---KIKSSHDVLNDPRLL-------KAEASDKERN 249

  Fly   257 LSDD------------CPEDSVKDKPSTASSDLI-----------------KMK---LSKRSKSG 289
            .|:.            ..|.:.||| |.:.||.:                 ||:   ||:|.:.|
plant   250 ASESKEVLSVREALNAKKEAAQKDK-SFSVSDTVGNSDDDDDGEDETKFDAKMRNQVLSRRKEIG 313

  Fly   290 ADKKVQPVEEKSDSEDDEDVLLTREE--EQSRKVSEEKSKIREEIASLKKQ--------YQMDKQ 344
             |...:|.::|..|.     |..|||  ::|..||.|..|.|.|..||||:        ..|:|.
plant   314 -DTPSKPTQKKKSSS-----LKGREESTQRSDAVSSEDEKPRMEKLSLKKKGIGSEAKAEHMEKG 372

  Fly   345 SKD-KLVNGQEKAAKSNEIKGSSENHYINDFIESKEKYTAKVKLQPKGQSREAFTLSLLSKFRTK 408
            ..| :|.|..|:|.:.:::|........:..:...||:...:..:|...|.|...|:
plant   373 DTDLQLYNASERARQLHKLKKRRLQGNEDSVLAKLEKFKQSISAKPFTSSNEPVVLT-------- 429

  Fly   409 LDNLKQKSSSDDGESEPKDIDDRVVEQEIIGDDWLSHTLNFNSTTPVLAKDANKKGDDWYDAYDP 473
                   |||:..:::.:|:           .||.:..|.|   .|...||...:.|| .|||..
plant   430 -------SSSEPVDNKEEDL-----------SDWKNVKLKF---APERGKDKMSRRDD-PDAYMV 472

  Fly   474 RNPLNKRKRGETGSSKSSSGKSKSSKRD 501
            .:||.     |.|..|.:..::|..:|:
plant   473 VDPLL-----EKGKEKFNRMQAKQKRRE 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10907	NP_648508.1	cyclophilin_CeCYP16-like	8..178	CDD:238906	104/171 (61%)
AT4G33060	NP_195032.2	cyclophilin_CeCYP16-like	8..180	CDD:238906	104/171 (61%)
AT4G33060	NP_195032.2	PTZ00121	<248..>497	CDD:173412	70/290 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	184	1.000	Domainoid score	I1009
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21192
Inparanoid	1	1.050	294	1.000	Inparanoid score	I818
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	1	1.000	-	-		FOG0005686
OrthoInspector	1	1.000	-	-		oto3978
orthoMCL	1	0.900	-	-		OOG6_102804
Panther	1	1.100	-	-	LDO	PTHR45625
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3553
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.830